ESTROGEN-replacement therapy has been shown to retard bone loss in postmenopausal women.^{1 2 3 4 5 6 7 8} Although some controversy still surrounds the relation between osteoporosis and hip fractures,^{9 , 10} several case–control studies have demonstrated a ...

HIGH fever (temperature ≥39.0°C) is one of the most common symptoms prompting medical visits of infants and toddlers. Most febrile children have self-limited viral illnesses, but between 3 and 15 percent have bacteremic infections, predominantly with ...

ASPARTAME is a dipeptide sweetener (L-aspartyl-L-phenylalanine methyl ester^{1 , 2}) that is 180 to 200 times sweeter by weight than sugar. The Food and Drug Administration approved the use of aspartame as a table-top sweetener and an ingredient in dry foods ...

NONRANDOM chromosomal abnormalities have been described in different histologic subtypes of non-Hodgkin's lymphomas.^{1 2 3 4 5} These studies have demonstrated a particularly high incidence of karyotypic abnormalities involving chromosome bands 14q32 and ...

HYPONATREMIA is a common clinical entity that may occur during the course of a variety of medical illnesses.¹ In the majority of patients, hyponatremia is mild and asymptomatic. However, severe symptomatic hyponatremia (serum sodium concentration, <120 ...

TWENTY-ONE years ago, in June 1966, Henry Beecher, Dorr Professor of Research in Anesthesia at Harvard Medical School, published in these pages an analysis of "Ethics and Clinical Research" and thereby accelerated the movement that brought human ...

THREE decades have elapsed since Zollinger and Ellison first described a syndrome characterized by a severe, often fatal, form of peptic ulcer disease accompanied by marked hypersecretion of gastric acid and non-β islet-cell tumors (gastrinomas) of the ...

Presentation of Case

A 16-year-old girl was admitted to the hospital because of hepatic and pulmonary masses.

She was well until two months earlier, when she began to experience abdominal pain of two types. One was localized in the epigastrium and at ...

Febrile illnesses are a part of growing up. Children may have three or more illnesses with fever in each of the first three years of life.¹ Most episodes are minor, will resolve without the use of antimicrobial agents, and are caused by a viral infection. ...

That I might be a pawn of fashion first came home to me about 10 years ago when a number of new nonsteroidal antiinflammatory drugs were being introduced. In October 1978, sulindac (Clinoril) was introduced to the market and to the public in a press ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Doubt has recently been raised about the existence of the syndrome of "chronic infectious mononucleosis."¹ That this disorder, which is characterized by persistent weakness and fatigue, anxiety or depression (or both), and disorders of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Sue et al. (May 21 issue)¹ reported on the inability of the diffusing capacity to predict abnormalities of gas exchange during exercise. I am concerned about two aspects of their study.

First, by using any one or more of four criteria to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In the late 1980s we are witnessing a freshet of revived interest in the history of American physiology, prompted partly by the centennial of organized physiology in this country. Scholars have recently produced several volumes on the rise of this central ...

No extract is available for articles shorter than 400 words.

The Role of Drug Treatments for Eating Disorders deals exclusively with the drug treatment of anorexia nervosa and bulimia, mentioning other problems only briefly. It is meticulously up to date, with bibliographic references up to 1986.

With this work, ...

Here, the author has taken on the unenviable task of single-handedly writing a textbook of immunology. On the whole, he has done an elegant job. His success derives from a number of factors: a solid grounding in immunologic research and principles, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In modern China, the predominant orientation in health care follows the model of Western scientific medicine. The history and delivery of health care in China, however, are different from those in the Western countries on which the current model is based. ...

Pediatrics

Adolescent Suicidal Behavior. (Series in Death Education, Aging, and Health Care.) By David R. Curran. 208 pp. New York, Hemisphere, 1987. $39.95 (hardcover); $19.95 (paper).

Children's Mental Health — Problems and Services: A report by the ...

EUROPEAN SOCIETY FOR MEDICAL DECISION MAKING

The conference will take place in Copenhagen, Denmark, June 1–4. Papers on aspects of medical decision making are invited.

Contact Annelise Nielsen, Inst. of Social Med., Univ. of Copenhagen, Panum Inst., ...

No extract is available for articles shorter than 400 words.

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...