HEREDITARY angioneurotic edema is a genetic disease resulting from a quantitative or functional defect of C1 inhibitor,¹ the only plasma protein controlling the intravascular activation of Cl, the first component of the classical pathway of complement.² ...

ALTHOUGH the medical literature since 1875 has included descriptions of new weakness occurring decades after paralytic poliomyelitis,^{1 2 3 4 5 6 7 8 9 10 11} it has recently become clear that the prevalence of new symptoms in the large cohort affected with ...

ALTHOUGH most forms of hyperthyroidism result from autoimmune stimulation of the thyroid gland, autonomous thyroid nodules, or variants of thyroiditis, inappropriate secretion of pituitary thyrotropin can also cause this condition.¹ Inappropriate ...

INFECTIONS due to penicillin-resistant pneumococci, defined as any strain of Streptococcus pneumoniae for which the minimal inhibitory concentration (MIC) of penicillin G is ≥0.l μg per milliliter, have been detected over the past 20 years in many ...

IS insurance for long-term care an idea whose time has come? Possibly. The recent explosion of publicity about insurance against catastrophic illness in the elderly, President Reagan's partial endorsement of Secretary Bowen's report favoring such ...

PATIENTS with immediate hypersensitivity reactions are commonly encountered by physicians in both primary care and various specialty practices. Such patients present a broad spectrum of illnesses, ranging in severity from mild urticaria or seasonal ...

Presentation of Case

First admission. A 53-year-old man was admitted to the hospital because of multiple bilateral pulmonary-nodules.

He was well until three years earlier, when symptoms of a respiratory tract infection were followed by a chronic ...

Nearly 100 years ago, on September 20, 1887, a 24-year-old woman was admitted to William Osier's service at the Philadelphia Infirmary for Nervous Diseases with chronic intermittent "attacks of transient swelling in various parts — hands or fingers, knee ...

Patients with pituitary adenomas present with diverse clinical syndromes related to the secretory activity of the tumor and the amount of residual normal pituitary tissue. Thyrotropin-producing pituitary adenomas are rare, but patients with this problem ...

Hospital ethics committees have been hailed as providing a promising way to resolve ethical dilemmas in patient care. Although ethics committees may have various tasks, such as confirming prognoses, educating care givers, or developing hospital policies, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A reduction in the size of pituitary adenomas has been suggested to occur in patients with acromegaly treated with a long-acting somatostatin analogue, SMS 201–995.¹ We observed rapid improvement in vision during SMS 201–995 treatment in a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The Sounding Board article by Yolles et al. (Dec. 25 issue)¹ concerning access to data from government-sponsored medical research raises a number of important issues. Unfortunately, the article is misleading with regard to studies of the ...

In the January 11, 1900, issue of the Journal, then still known as the Boston Medical and Surgical Journal, a lengthy article by Walter B. Cannon, a senior student at the Harvard Medical School, was featured. Cannon argued for an important reform in the ...

Here is a beautiful and remarkable — if expensive — book. This encyclopedia, one of the world's leading works on all aspects of science for the lay reader, now appears in a new edition after five years and in celebration of the 25th anniversary of the ...

Endemic diseases and the more frightening epidemic diseases have puzzled humanity for millennia. Hippocratic theories about the effect of atmospheric and environmental factors on the human constitution prevailed for centuries. With the scientific ...

It has been said that the only ethical advice the philosopher Ludwig Wittgenstein ever gave was "travel light." In this book, some of our more oppressive cultural baggage is highlighted, as we join the author on what he calls an "odyssey in inner space to ...

This is a difficult book to review. For one thing, the author is obviously in love with his subject. As the physician who wrote the introduction has said, Dr. Kail has written for the "joy of it, reflecting the delight he has had as an enthusiastic ...

This is a short book about a major scientific fraud. Details of the crime vary and will probably never be clarified satisfactorily, but it seems to have begun in 1908 with a British laborer's discovery of a human parietal bone at a gravel pit located on ...

Here is an account of events during and after the construction of a three-mile tunnel through Gauley Mountain, West Virginia, a third of it through almost pure silica rock. Tunneling began on the last day of March, 1930, and was completed 17 1/2 months ...

Biomedical Science

Acceptability of Cell Substrates for Production of Biologicals. (WHO Technical Report Series 747.) Report of a WHO study group. 29 pp. Geneva, World Health Organization, 1987. (Available in the U.S. from the WHO Publications Center USA, ...

FINANCIAL MANAGEMENT

A course entitled "Your Practice and Financial Management" will be offered in Hilton Head Island, S.C., Aug. 3–8.

Contact Div. of Cont. Educ., Med. Coll. of Georgia, Augusta, GA 30912–6450; or call (800) 221–6437 (national), or (404) ...

No extract is available for articles shorter than 400 words.

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...