HUNTINGTON'S disease is a progressive and fatal neurologic disorder with dominant inheritance and apparently complete penetrance. Clinical symptoms typically do not develop until the third or fourth decade of life.^{1 , 2} At birth, each offspring of an ...

THE occurrence of proximal-femur (hip) fracture in elderly persons is influenced by both age-related bone loss and the risk of falling.^{1 2 3 4} The use of psychotropic drugs has been hypothesized to increase the risk of hip fracture by increasing the ...

EARLY observations of neuroparalytic accidents due to rabies vaccines provided a foundation for current concepts of immunopathological mechanisms in demyelinating diseases. The encephalomyelitis and polyneuritis complicating the use of vaccines prepared ...

EACH year in the United States there are approximately 300,000 new cases of duodenal ulcer, about 3.2 million recurrences, and 3000 deaths due to the disease.¹ In spite of the high prevalence and inherent economic costs of duodenal ulcer, estimated at ...

THE metabolic impact of infectious and neoplastic disease states has long been known to clinicians.^{1 2 3 4} Invasive diseases may disrupt normal homeo-static mechanisms, both locally and systemically. For example, acute gram-negative infections frequently ...

INTERNATIONAL comparisons of cesarean rates are hindered because few countries routinely publish information on their rates of cesarean delivery. Thus far, the handful of comparative studies have been constrained by the fact that only limited social, ...

GüNTHER'S disease, or congenital erythropoietic porphyria, is a rare autosomal recessive disorder of heme biosynthesis characteristically associated with diminished uroporphyrinogen III cosynthetase activity.^{1 , 2} Disfiguring photomutilation starts in ...

Presentation of Case

A 46-year-old woman was admitted to the hospital because of abdominal pain.

She was well until the morning of admission, when she experienced the abrupt onset of diffuse abdominal pain, without nausea or vomiting. She passed a normal ...

The fractures most commonly associated with osteoporosis occur in the vertebrae, hip, and distal forearm. Of these, hip fractures have by far the most severe consequences. In 1985, about 247,000 hip fractures occurred among persons over age 45 in the ...

ON July 6, 1885, Joseph Meister, age nine, was brought by his mother to Louis Pasteur. The day before, he had been bitten 14 times by a rabid dog. Pasteur boldly treated the boy with a rabies-prophylaxis technique that he had been studying in dogs. ...

Duodenal ulcer is the most common form of ulcer disease. Gastric acid is necessary for the formation of duodenal ulcers ("no acid, no ulcer"), and in some patients (those with acid hypersecretion), acid itself may be sufficient to induce the ulcer. It has ...

To the Editor: Austria was among the countries with the highest amounts of radioactive materials deposited after the Chernobyl accident on April 26. Doses of radioactivity received through ingestion involve mainly ¹³¹I, ¹³⁴Cs, and ¹³⁷Cs. Although the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Evidence suggests that an alteration of benzodiazepine receptors in the brain may have a role in the pathophysiology of hepatic encephalopathy. A twofold increase in the density of cerebral benzodiazepine receptors occurs during ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is an accurate, highly readable, and up-to-date account of a fascinating disease, which generally fulfills the promise of its title. The defects in coverage are few and minor. This is an authoritative account of the important aspects of the rabies ...

No extract is available for articles shorter than 400 words.

These two books — the first written by a medical sociologist, the second by a journalist — examine a question asked commonly these days: Is medical technology all that wonderful? The answer, in both cases, is a resounding "not really."

Plough's effort, ...

This book is a joy to read and to review. The content, with a few minor exceptions, is excellent. Its conception, format, and execution are at least as important as its treatment of a heretofore neglected subject in medical ethics. For those of us ...

Why would Richard Selzer choose to rewrite his version of Thomas Mann's "The Black Swan" as 1 of 12 pieces in his new book? Partly out of homage to Mann, but primarily, Selzer avers, because of a scene he encountered in his hospital practice. That image ...

CLINICAL MANAGEMENT OF THE ELDERLY PATIENT

The symposium will be held in Lake Buena Vista, Fla., March 12–14.

Contact the Health and Education Council, 7201 Rossville Blvd., Baltimore. MD 21237; or call (301) 686–3610.

UNIVERSITY OF CALIFORNIA AT DAVIS ...

No extract is available for articles shorter than 400 words.