THE proportion of human oocytes with chromosomal abnormalities is not yet known. However, chromosomal imbalance has been suggested to be one important factor contributing to the estimated high rate of fetal wastage (about 60 percent), which occurs mostly ...

A NEW syndrome, hereditary hypophosphatemic rickets with hypercalciuria (HHRH), was recently described in closely related members of a Bedouin tribe.¹ It is characterized by rachitic skeletal deformities and abnormalities of phosphate and calcium ...

THE total artificial heart with which there has been the most clinical experience is the Jarvik-7. This device represents the culmination of decades of work by Willem Kolff, recently with Donald Olson and Robert Jarvik, and the surgical experience of ...

PEDIATRIC intensive care has evolved rapidly in recent years. The number of pediatric intensive care units (ICUs) has grown steadily, and the resources and expertise necessary for higher levels of care have developed simultaneously. This evolution has ...

IT has long been held that systemic acidemia provides the proximate stimulus for the kidney to increase urinary acidification in response to metabolic acidosis.^{1 2 3 4} This view has been challenged by the experimental work of Schwartz and associates,^{5 6 7} ...

ACUTE pancreatitis is usually distinguished from chronic pancreatitis by assessing whether the pancreas was normal in structure or function before the onset of the disease.¹ In the United States, chronic pancreatitis is most often associated with chronic ...

Presentation of Case

A 17-year-old girl was admitted to the hospital because of a possible brain-stem lesion.

She was in excellent health until one year earlier, when she slipped and fell on the lower portion of her back while performing on uneven ...

IN this issue Wramsby et al.¹ describe chromosomal analysis of 23 human preovulatory oocytes and suggest that as many as half may have had an abnormal karyotype. This is an example of how the analysis of early human embryonic development is becoming ...

AT the beginning of this century, a distinguished Boston surgeon, Ernest Amory Codman, waged a courageous but unsuccessful campaign to have surgeons and hospitals record and publicize the results of their operations. Some seven decades later, the Joint ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We are not surprised that Frigoletto et al. report good outcomes without intrauterine transfusion in pregnancies with rhesus sensitization, described in their recent article (Aug. 14 issue).¹ Except for one value of 0.395, the amniotic-...

To the Editor: Herpes zoster usually occurs in elderly or immunocompromised patients. More recently, it has been reported in homo-sexuals and patients at risk for the acquired immunodeficiency syndrome (AIDS), with and without biologic evidence of immune ...

To the Editor: Gordon et al.¹ (Aug. 14 issue) reported the effects of indomethacin on excessive secretion of plasma atrial natriuretic peptide (ANP) in Bartter's syndrome. We measured plasma ANP concentrations in a 27-year-old woman with pseudo-Bartter's ...

No extract is available for articles shorter than 400 words.

Scientific progress, whether technical or intellectual, leads to a succession of specializations. The fields of geriatric medicine and gerontology are no exceptions. The abuse and neglect of older adults, like the mistreatment of children, have led to ...

Recognizing that the era of the blank check for medical care has ended, Mechanic argues that we must find judicious and humane ways of allocating limited resources. He develops this theme in this book of essays.

The book's strengths are Mechanic's ...

Rashi Fein introduces the reader to health care economics in the opening sentence of his book: "Health care policy is part of social policy." This statement becomes the focus of this fascinating history of private and government involvement in the ...

Surely a major component of judgment is knowing when not to do what one in fact can do. This problem increasingly confronts health care practitioners as the technical frontiers of intervention expand. Two useful books are now available that are important ...

As one of the contributors to this fine new book asserts, "Administering mechanical nutrition and hydration is no picnic." Neither is the responsibility for grappling with the bedeviling decisions concerning whether to withhold artificial means of ...

ADVANCES IN INFERTILITY AND REPRODUCTIVE ENDOCRINOLOGY

The course will be offered in Mount Crested Butte. Colo., Feb. 14–20.

Contact Sher Reed. CME Div., Vanderbilt Univ. School of Med., Nashville, TN 37232; or call (615) 322–4030.

RADIOLOGY

A program ...