ATAXIA-TELANGIECTASIA is a distinctive autosomal recessive syndrome characterized by progressive cerebellar ataxia and oculocutaneous telangiectasias.¹ Patients with this syndrome have an unusually high incidence of cancer, particularly lymphomas and ...

THE existence of 17-ketosteroid reductase, which converts the precursor hormone androstenedione to the product hormone testosterone and converts estrene to estradiol in human adrenal and gonadal tissue, is well known. Furthermore, a genetic defect or ...

THE increased metabolic demands of exercise are accompanied by considerable increases in pulmonary perfusion and ventilation. Regional increases in perfusion are well matched with increased ventilation in persons with normal lungs, as evidenced by normal ...

SUCRASE–ISOMALTASE deficiency is regarded as the most frequent primary disaccharidase deficiency of childhood with autosomal recessive inheritance.¹ It causes malabsorption of sucrose, with diarrhea, abdominal cramps, and bloating, resulting from the ...

STRENUOUS exercise, a component of the primitive "fight or flight" response, is a challenge to homeostasis. Two chief stress-activated systems, the autonomic nervous system (with its endocrine component, the adrenal medulla) and the hypothalamic–pituitary–...

IN 1975 the Federal Trade Commission (FTC) successfully sued the American Medical Association (AMA), charging it with the unlawful restriction of advertising by its physician members. This suit and its attendant issues spawned a barrage of arguments over ...

THE physician has difficulty in coming to grips with the basic concepts of immunology, and the reasons for this are partly historical. Most of the major medical specialties (e.g., cardiology, neurology, and gastroenterology) deal with organ systems that ...

Presentation of Case

A 68-year-old man was admitted to the hospital because of progressive weakness and weight loss.

He was well until approximately one year earlier, when he began to experience progressive weakness that began in the hands; later he had a ...

IN these heady days of molecular biology, one almost needs to apologize for an interest in pulmonary gas exchange. Those of us who work in this area are sometimes criticized for not moving to one of the newer areas of pulmonary research¹ aimed at ...

There was a time when it appeared to be relatively easy to comprehend immunology. Reflecting the historical successes of cowpox inoculation against smallpox, of rabies and polio vaccines, and of passive immunizations with antitoxins, immunity came to mean ...

Sexually transmitted diseases have never been eliminated as a public health problem. However, the lethality of the acquired immunodeficiency syndrome (AIDS), a sexually transmitted disease, poses unique challenges. Voluntary testing of all sexually active ...

No extract is available for articles shorter than 400 words.

To the Editor: Harper et al. (Oct. 23 issue)¹ describe a patient with T8-cell proliferation who was concomitantly infected with human T-cell lymphotropic virus Type I (HTLV-I) and Type III (HTLV-III). However, the order of infectivity was not ...

To the Editor: The report by Tallarigo et al. (Oct. 16 issue)¹ that even limited degrees of maternal hyperglycemia, currently considered to be in the normal range, may affect the outcome of pregnancy, is intriguing. However, careful analysis of the data ...

No extract is available for articles shorter than 400 words.

To the Editor: Pauls and Leckman conclude that Gilles de la Tourette's syndrome, as defined by them, is inherited as an autosomal dominant trait (Oct. 16 issue).¹ On the basis of this conclusion, they indicate that "the next step in understanding the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

At first glance, this intriguing title can mislead. It is not a description of the psychic struggles of patients with syndromes. It is, rather, an alphabetical collection of syndromes and the physicians who discovered, described, or named them. Of the 210 ...

Here is a book that confronts head-on the problems of fraud, failure, deceit, deception, mistake, and misapprehension in scientific research. Although the book is small, it is encyclopedic in scope, referring back to manipulations of data allegedly ...

There are still relatively few books available that deal with topics in human cytogenetics, despite the fact that amniocentesis for karyotype analysis has become widely known. The fast pace in this field (which now includes prenatal diagnosis by chorionic ...

This is the third edition of a textbook directed to undergraduate students in medical technology and clinical chemistry. It consists of three principal sections and an appendix that includes large reference tables for clinical chemistry, toxicology, and ...

No extract is available for articles shorter than 400 words.

Dermatopathology is currently among the most diverse, complex, and rapidly progressing fields of medicine. Not only are there thousands of diagnostic possibilities each time a specimen is examined, but there are now many new methods for establishing or ...

No extract is available for articles shorter than 400 words.

MEDICAL ONCOLOGY AND HEMATOLOGY: RECENT ADVANCES

The course will be offered in Kiawah Island, S.C., June 29–July 2.

Contact Div. of Cont. Educ., Med. Coll. of Georgia, Augusta, GA 30912–6450; or call (800) 221–6437 (national) or (404) 828–3967 (Georgia).

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