RISK factors for infection with human immunodeficiency virus (HIV) have been identified and widely publicized.¹ However, the risk that the acquired immunodeficiency syndrome (AIDS) will develop in a given period following HIV infection has been estimated ...

MULTIPLE sclerosis is a chronic disease of the central nervous system,^{1 2 3} characterized pathologically by demyelination of white matter associated with a mononuclear-cell infiltrate that consists predominantly of T cells and macrophages.^{4 5 6} Although ...

ANEMIA is a major and predictable complication of chronic renal failure. When end-stage renal disease evolves, the anemia is frequently severe and often impairs rehabilitation despite adequate dialysis therapy. Approximately 25 percent of patients ...

IT is becoming increasingly evident that most human leukemias and lymphomas are associated with characteristic chromosomal abnormalities.¹ They often involve either a reciprocal chromosome translocation, which may lead to oncogene deregulation, or a ...

THE efforts of the medical research community to determine the value of skull radiography after head trauma have been substantial. Numerous studies of the efficacy of skull radiography in assessing head trauma, conducted after the publication of Bell and ...

Presentation of Case

A 30-year-old man was admitted to the hospital because of fever and dysphagia.

The patient was born of a second pregnancy that was complicated by vaginal bleeding in the second month. His birth weight was 3.4 kg. The child appeared ...

Since 1957, when Jacobson and associates¹ demonstrated the renal origin of erythropoietin, it has been assumed that the anemia of chronic renal disease is caused at least in part by a deficiency of this renal hormone and that it might be corrected if ...

In the 1920s and 1930s, the pediatrician Clara Davis conducted pioneering studies, now considered classic, and published at least 12 papers on the selection of diets by infants and young children.^{1 2 3 4} The results of her research have been widely ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The gene responsible for Duchenne muscular dystrophy encodes an mRNA of about 16 kb (kilobases).¹ If the message encodes a single protein, the protein would be about 500 kd in size. The largest known proteins in muscle are nebulin (550 kd) ...

To the Editor: The conclusions of the paper by Arthur et al. (July 24 issue),¹ ascribing hemorrhagic cystitis in recipients of bone marrow transplants to the activation of BK type human polyomavirus, may be interpreted differently. The virus forms ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: There are a number of case reports of patients with hairy-cell leukemia in whom the nephrotic syndrome developed during the course of the illness.^{1 , 2} Previously described histopathological processes include IgA nephropathy,¹ amyloidosis,^...

To the Editor: The assessment of helper (CD4):suppressor/cytotoxic (CD8) T-lymphocyte ratios is an increasingly popular method to monitor immune competence in various patient groups. The "normal" CD4:CD8 ratio is generally 2.0 (range, 1.5 to 3.5). Ratios ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Samuel Thielman makes some very insightful comments in his July 24, 1986, review of Great and Desperate Cures,¹ especially when he points out the book's lack of historical process. The author of the book, Elliot Valenstein, omits important ...

Few physicians today would question the usefulness of the thermometer in the practice of medicine. It was adopted into widespread use within a relatively short period in the mid-19th century, partly because of the work of such prominent persons as Traube ...

Bernard Davis' collection of his essays, letters, editorials, and reviews written between 1970 and 1985 is a tapestry of important events and controversies about the relations between science, medicine, and society. Often, it reads like a diary, for these ...

No extract is available for articles shorter than 400 words.

This book is an atlas of electron microscopical studies of human neoplasms, written for the practicing surgical pathologist. Its approach to diagnosis is based on photographs of the ultrastructural features of histogenetically related groups of neoplasms, ...

No extract is available for articles shorter than 400 words.

This is yet another in the ever-expanding library of monographs on biopsy pathology. As the author notes in his preface, the advent of fiberoptic endoscopy has increased the number of biopsy specimens of the gastrointestinal tract seen by the general ...

This book is interesting on a number of counts. Its central concept is that if the surgeon and surgical pathologist have excellent communication, mutual respect, and some understanding of the techniques and limitations of both disciplines, better patient ...

No extract is available for articles shorter than 400 words.