ACUTE neurotoxic effects during the cholinergic phase of organophosphorus poisoning are well known. Also recognized are the delayed neurotoxic effects usually manifested as distal motor polyneuropathy.¹ This paper describes an intermediate syndrome of ...

THE reformulation in 1982 of a form of levothyroxine, Synthroid (manufactured as tablets by Flint, Inc., Deerfield, Ill.), raised considerable concern about the tablet strength and bioavailability of currently available preparations. In 1984 Staffer and ...

THE incidence of measles (rubeola) in the United States is now less than 1 percent of what it was before the introduction of a vaccine. Despite the adoption and enforcement of school immunization requirements in every state, however, outbreaks continue to ...

IN nephropathic cystinosis, a rare lysosomal storage disease, cystine accumulates within cells to levels 50 to 100 times normal.^{1 2 3} The basic defect of this autosomal recessively inherited disorder is an impairment of normal carrier-mediated transport ...

(First of Two Parts)

HYPERTROPHIC cardiomyopathy has fascinated and often confused physicians for the quarter of a century since its recognition in the late 1950s.^{1 2 3 4 5} During this time, investigators have assembled an impressive array of observations ...

ANTIBODY directed to the capsular polysaccharides of pneumococcus, meningococcus, and Hemophilus influenzae type b is protective against these bacterial pathogens.^{1 2 3} In most adults the antibody response to polysaccharide antigens predominantly involves ...

PATIENTS with a severe, dilated cardiomyopathy with congestive heart failure have a poor prognosis unless a correctable cause can be identified. Even when a cause is found, the degree of reversibility of myocardial injury is uncertain.¹ We describe a 12-...

Presentation of Case

First admission. A 20-year-old man was admitted to the hospital because of facial swelling and leukemia.

He was well until two weeks earlier, when he began to notice swelling about the left ear, accompanied by a headache. The ...

Since 1945, some 15,000 individual compounds and more than 35,000 different formulations have come into use as pesticides. During this period, as a result of the widespread use of these agents, and particularly the organophosphorus insecticides, ...

ON November 7, 1985, the Journal published the results of a randomized trial of extracranial–intracranial (EC–IC) arterial bypass surgery to reduce the risk of ischemic stroke in patients with symptomatic atherosclerotic disease of the internal carotid ...

This book holds out rich promise of becoming a landmark publication in health policy. Because of the author's background (he was Secretary of the Department of Health, Education, and Welfare [DHEW] in 1977–1979), we expect a lot. He tells of his success ...

This book addresses a subject of paramount social importance: contracting for the care of the poor on a prepaid basis. Several states have introduced such systems into their programs of care of the indigent. The federal government has looked favorably on ...

This book, written by a professor of history and sociology at the University of Wisconsin, has many strengths and a few weaknesses. Among its strengths is the central question that the author has explored: What explains the different paths traveled by the ...

This collection focuses on the application of social research methods and theory to the acquired immunodeficiency syndrome (AIDS). Increased scientific knowledge and changes in public understanding since late 1985 have already outdated some of the papers.

During the course of this century, several key leaders of governments either became very aged and infirm or had a serious illness. It is said that Woodrow Wilson was confused at the Paris Peace Conference and that Adolf Hitler took amphetamines. After ...

No extract is available for articles shorter than 400 words.

NATIONAL CONFERENCE ON HIGH BLOOD PRESSURE CONTROL

The conference will be held in Las Vegas, Nev., April 24–26.

Contact National Conference on High Blood Pressure Control, 2121 Wisconsin Ave. NW, Suite 410, Washington, DC 20007; or call (202) 944–3176.

...

The international, multicenter, randomized trial of extracranial–intracranial arterial anastomoses (EC–IC bypass)^{1 , 2} has been applauded and cited as a standard for future studies of this type.³ The eminence of the primary investigators, the multiple ...

The Extracranial–Intracranial (EC-IC) Bypass Study was organized and conducted by Henry Barnett and colleagues at the University of Western Ontario and McMaster University under a grant from the National Institute of Neurological and Communicative ...

The dramatic results of the extracranial–intracranial (EC–IC) bypass trial have stimulated the vigorous discussion and debate that are essential to the pursuit of truth and the advancement of useful clinical knowledge.^{1 2 3} We therefore thank Dr. Sundt ...