Evidence accumulated in the past five years has confirmed the initial finding of de Bold et al.¹ that mammalian atrial cardiocytes contain a potent natriuretic factor. This atrial factor has been identified as peptides that possess natriuretic,² ...

Approximately 50 percent of patients with childhood acute lymphoblastic leukemia (ALL) are cured with chemotherapy.¹ The others have recurrent disease that is ultimately fatal, unless bone marrow transplantation is successful.^{2 3 4} Currently, most centers ...

Amenorrhea is a common clinical problem afL fecting between 1.8 and 3.3 percent of young women, and hyperprolactinemia occurs in 25 to 30 percent of such women.^{1 2 3} Ovulatory dysfunction and galactorrhea are known consequences of hyperprolactinemia, and ...

The adult respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage that may occur after a variety of serious diseases, injuries, or burns. Approximately 150,000 cases a year are identified in the United States, and the mortality is ...

The prompt initiation of empirical broad-spectrum antibiotic therapy when a patient with neutropenia becomes febrile has resulted in a significant reduction in morbidity and mortality.^{1 , 2} A combination of antibiotics has been considered necessary to ...

The heterogeneity of the natural history of breast cancer is generally recognized, but its determinants are largely unknown. It has not yet been established, for instance, whether the aggressiveness of the tumor and thus the course of the disease after ...

Although X-linked agammaglobulinemia was one of the first immunodeficiencies described,¹ the genetic defect responsible for this disorder has not yet been identified. X-linked agammaglobulinemia is characterized by the onset of recurrent bacterial ...

Presentation of Case

A 62-year-old right-handed woman was admitted to the hospital because of left hemiparesis.

She was well until seven months earlier, when right-sided headaches developed. She entered another hospital, where a left visual-field defect ...

In 1982, we reviewed current concepts of the pathogenesis of the adult respiratory distress syndrome (ARDS).¹ At that time, the role of the intravascular activation of circulating blood leukocytes, especially granulocytes, was a topic of burgeoning ...

The definitive test of a new empirical antimicrobial regimen is the treatment of bacterial infection in a febrile patient with neutropenia. An increasing number of antimicrobial agents are used for empirical therapy in such patients, and controversy about ...

To the Editor: The roles of state and local health departments' alternative test sites and nonalternative test sites (physicians' offices, clinics, and hospitals) in screening nondonors for antibody to human immunodeficiency virus (HIV, or HTLV-III/LAV) ...

To the Editor: In the April 24 issue of the Journal, Stricof and Morse reported a well-documented case of HIV (HTLV-III/LAV) seroconversion in a health care worker after a needlestick injury.¹ A Special Report evaluating the occupational risk of acquired ...

No extract is available for articles shorter than 400 words.

To the Editor: There have been numerous reports of adverse reactions to nifedipine, including transient hypotension, tremors, muscle cramps, and dizziness.¹ However, none to date has included tetany. Our recent experience with nifedipine presents a ...

To the Editor: Danazol (Danocrine) is a synthetic androgen approved for use in the treatment of fibrocystic breast disorder, endometriosis, and hereditary angioedema. It has also been used in the treatment of chronic immune thrombocytopenic purpura (ITP)...

No extract is available for articles shorter than 400 words.

To the Editor: Data regarding the influence of age on prognosis in breast cancer appear to conflict, with some studies reporting better survival among young women^{1 2 3 4 5} and others reporting an improved prognosis among older women.^{6 7 8 9 10 11} We ...

To the Editor: We have obtained more data on the association of coffee and pancreatic cancer since a paper by some of us was published in the Journal in 1981.¹

A case–control study was conducted between April 1981 and June 1984 in 11 large hospitals in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The first book here covers the disorders of the hematologic system that affect both mother and fetus. It is divided into a confusing series of chapters. Although there is much information on the evaluation, treatment, and diagnosis of hematologic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Originally a surgical stepchild, gynecology has evolved from the traditional view that its specialists served as the guardians of a woman's reproductive potential to a dynamic, scientifically grounded discipline providing primary health care to women and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Medicine

Prolactinomas. (Contemporary Issues in Endocrinology and Metabolism. Vol. 2.) Edited by Jerrold M. Olefsky and Richard J. Robbins. 230 pp., illustrated. New York, Churchill Livingstone, 1986. $36.

Recent Advances in Rheumatology. No. 4. Edited by ...

CARDIOVASCULAR DISEASE

A course entitled "Stress and Cardiovascular Disease" will be offered in Sacramento, Calif., on Sept. 19.

Contact CME Office, UC Davis, School of Med., 2701 Stockton Blvd., Sacramento, CA 95817; or call (916) 453–5390.

ASBESTOS

A ...

No extract is available for articles shorter than 400 words.

In 1948 the General Assembly of the United Nations established the United Nations Relief for Palestine Refugees (UNRPR) agency to coordinate relief activities among refugees from the Arab–Israeli conflict. In 1949 the General Assembly replaced UNRPR with ...