BECAUSE leukoplakia may precede invasive carcinoma by months or years or may accompany overt carcinomas, it is assumed to be etiologically associated with oral cancer as a premalignant lesion.^{1 2 3 4 5 6} Malignant transformation occurs in as many as 3 to ...

IN approximately 30 to 50 percent of women who seek medical help for infertility, a tubal abnormality is found to be the cause of the inability to conceive.¹ There is reason to believe that undergoing appendectomy may place a woman at increased risk of ...

APOLIPOPROTEIN B is the principal protein of low-density lipoprotein (LDL).¹ It exists in two major forms derived from the liver (B-100) and small intestine (B-48). B-100, with a molecular weight of 550,000, is the determinant in LDL responsible for ...

THE recognition of drug-induced acute interstitial nephritis is difficult, because the complete clinical syndrome of fever, rash, and eosinophiluria accompanying acute renal failure is present in only one third of the cases.^{1 2 3} It has been claimed that ...

THE precise functions of dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), the major secretory products of the human adrenal gland, are uncertain. A striking linear decrease in the plasma levels of these so-...

LITTLE is known about the demographic origins, personal characteristics, educational background, or history of medical school application of U.S. citizens who enroll in foreign medical schools and progress far enough to seek to return to the United States ...

Presentation of Case

A 41-year-old woman was admitted to the hospital because of a continuous cardiac murmur.

The patient was born of an unusual gestation and delivery, in that her mother stated that she had had regular menses until the seventh month of ...

"Oral leukoplakia" is a term used to describe reasonably common, nonspecific, white plaque-like areas of oral mucosa, which develop in response to local irritation. The implications of leukoplakia as a precancerous condition and its relation to smoking ...

Although an editorial in the Journal 20 years ago implied heady times approaching in the treatment of appendicitis,¹ token recognition and no excitement greeted the 100th anniversary of the codification of the appendicitis syndrome last June.^{2 , 3}

In ...

Derrick — William Sheldon Derrick, M.D., formerly of Waban, died on May 25 at the age of 70.

Dr. Derrick received his degree from George Washington University School of Medicine in 1942. He was a member of the American Medical Association, the American ...

To the Editor: Isolates of Neisseria gonorrhoeae that are highly resistant to tetracycline but susceptible to penicillin and spectinomycin were recently reported in Georgia, Pennsylvania, and New Hampshire.¹ A similar strain (or strains) appeared in ...

To the Editor: During seroconversion to human immunodeficiency virus (HIV, or HTLV-III/LAV), we have noted a "window period" of low sensitivity with the enzyme-linked immunosorbent assay (ELISA) as compared with confirmatory serologic assays. The ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: It is known that human reproduction is associated with considerable early embryonic loss. Some reports suggest that up to 60 percent of embryos lack the potential for successful implantation.¹ It has also been observed that the pregnancy ...

No extract is available for articles shorter than 400 words.

To the Editor: Swimming has become an increasingly popular sport among young people in the United States. Many children, ranging from those in elementary school through college students, are involved in competitive swimming programs, which emphasize the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Neurofibromatosis consists of at least two distinct autosomal dominant hereditary disorders.¹ Von Recklinghausen's, or peripheral, neurofibromatosis is characterized by the development during the first and second decades of café au lait ...

To the Editor: Clark and coworkers report on the poor survival of patients with myelodysplastic syndromes presenting with a hypodiploid DNA stem line (June 5 issue).¹ We would like to take issue with several of the authors' results and conclusions.

First,...

No extract is available for articles shorter than 400 words.

To the Editor: Although ascites can be detected accurately by ultrasound examination, it is often difficult to detect by the conventional methods of physical examination. Suggestive findings include bulging flanks, flank dullness, shifting dullness, and ...

In what would have been Paul Dudley White's centennial year, Oglesby Paul has written a charming book about this simple but influential man. Paul White was the preeminent cardiologist of his time. Cardiology was sanctioned as a legitimate medical ...

No extract is available for articles shorter than 400 words.

Pacemakers represent one of the major technical advances in cardiology. Whereas pacemakers were originally used as a standby protection from Stokes–Adams attacks in complete atrioventricular block, their uses have gradually been extended to a broad ...

This textbook is a comprehensive introduction to molecular genetics and cell biology. It is designed for use in a challenging one-year course for college undergraduates. Physicians looking for an authoritative and wide-ranging survey of the "new biology" ...

In his preface, Schrier states that the central theme of his book remains the "pathophysiologic understanding of disease. . . the knowledge of which will allow for a more logical approach to the diagnosis and treatment of renal disease states." This book ...

No extract is available for articles shorter than 400 words.

Developing a resource and reference book for the patient with cancer is a worthy endeavor and a challenging one. Cancer is difficult to live with not only because to many it represents a death sentence, but also because it affects the whole family and is ...

Biomedical Science

Antigenic Variation in Infectious Diseases. (Special Publications of the Society for General Microbiology. Vol. 19.) Edited by T.H. Birkbeck and C.W. Penn. 170 pp., illustrated. McLean, Va., IRL Press, 1986. $58 (hardcover); $36 (...

THE TERMINAL NERVE: STRUCTURE, FUNCTION AND EVOLUTION

The course will be offered in New York, Feb. 2–4.

Contact Conference Dept., New York Acad. of Sciences, 2 E. 63rd St., New York, NY 10021.

CALL FOR PAPERS

Abstracts are now being accepted for the 5th ...

Efforts to contain the epidemic of the acquired immunodeficiency syndrome (AIDS) have concentrated on preventing the transmission of human immunodeficiency virus (HIV, or HTLV-III/LAV), since neither curative therapies nor vaccination is likely to become ...