Therapies currently available for the myeloid blast phase of chronic granulocytic leukemia are ineffective,^{1 2 3} and therapy for the lymphoid blast phase is only transiently effective.^{4 , 5} As a consequence, the median survival of patients with chronic ...

"RECREATIONAL" use of cocaine in the United JLV States has reached epidemic proportions; 22 million, or 1 in 10, Americans report that they have used cocaine at least once,^{1 , 2} and 5 million reportedly use it regularly.³ Despite previous reports ...

Neurotoxic envenoming by snakes is common in some parts of the world and may lead to fatal respiratory paralysis. Cobras (genus, naja) and kraits (genus, bungarus) are the principal causes of snakebite deaths in India, Sri Lanka, and Southeast Asia.^{1 2 3} ...

There is no effective treatment for primary biliary cirrhosis, a chronic, usually progressive cholestatic liver disease of unknown cause.¹ A number of therapeutic agents have been evaluated, but none has proved to be effective. Corticosteroids improve ...

Vulvovaginal infection due to candida species continues to be a worldwide problem, particularly in tropical climates.¹ Even in temperate regions, it has been estimated that up to 75 percent of women will have at least one episode of candidal vaginitis ...

Reproductive function in humans changes markedly during life and is usually divided into four stages. During the initial stage, which begins early in fetal life and ends in infancy, gonadotropins and gonadal steroids are secreted at levels similar to ...

Presentation of Case

A 20-year-old woman was admitted to the hospital because of systemic lupus erythematosus and respiratory distress.

The patient was a native of Cambodia and had resided temporarily in Thailand. There was a history of hepatitis at the ...

The course of chronic myelocytic leukemia (CML) has changed little since the initial description by Minot in 1924.¹ In the chronic state there is excessive proliferation of myeloid cells without loss of their capacity to differentiate. Neoplastic ...

For a number of years, there has been concern about the contribution to the cost of medical care of new technologies and the increasing use of old ones.^{1 2 3 4 5 6} Within the general framework of concern about medical technology, it is my purpose to ...

No extract is available for articles shorter than 400 words.

To the Editor: The recent deaths from cocaine ingestion of two prominent sports figures have publicized the potentially fatal cardiac toxicity of stimulant drugs. Although the doses and routes of administration involved are unknown at this time, we have ...

No extract is available for articles shorter than 400 words.

To the Editor: Despite a striking similarity between the symptoms associated with hypothyroidism and those occurring in premenstrual syndrome (PMS), including dysregulation of temperature, weight gain, lethargy, irritability, moodiness, and anxiety, ...

To the Editor: Transplantation of allogeneic tissue from one human into another normally leads to a cell-mediated immune response that rejects the transplanted tissue.¹ We report a case of accidental injection of a human colonic adenocarcinoma cell line ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

These two recent books are linked by several similarities. Each surveys a relatively narrow field of gastrointestinal radiology. Each suffers to a degree from the apparently inevitable overlap typical of multiauthored works. In small doses, repetition is ...

This book covers several aspects of the lymphatic system. It is ambitious and impressively successful in presenting the lymphatics as a whole, rather than confining itself purely to imaging. In this expanded (second) edition, lymphangiography is covered ...

Thousands of vascular laboratories in the United States currently use noninvasive techniques to study arterial and venous disease. There were probably fewer than 200 such laboratories a decade ago. This proliferation of testing facilities has been ...

No extract is available for articles shorter than 400 words.

Pediatric radiology has expanded rapidly to embrace the new imaging techniques. Specialists in this field must become "imagers," using techniques such as ultrasound, computed tomography (CT), and magnetic resonance. This major change is reflected in these ...

No extract is available for articles shorter than 400 words.

ADOLESCENT PSYCHIATRY

The 13th Annual Midwinter Program in Continuing Medical Education for Psychiatrists with a Special Focus on Adolescent Psychiatry, will be held in Incline Village, Nev., Jan. 25–30.

Contact CME Office, UC Davis, School of Med., 2701 ...

The earliest known use of cocaine, as suggested by the finding of coca leaves in the tombs of Indian mummies, was in 600 A.D.^{1 2 3} For centuries, the large population of Indians in Peru have chewed coca leaves. Although the first reported medicinal use of ...