ALTHOUGH little is known about the pathogenesis of the idiopathic inflammatory myopathies, a considerable body of evidence suggests that the intra-muscular microvasculature may be the site of primary involvement in childhood dermatomyositis and possibly ...

LEFT ventricular hypertrophy is a serious complication of a sustained elevation of blood pressure. In the Framingham Study, left ventricular hypertrophy, identified by electrocardiography, was associated with a risk of death from cardiovascular disease ...

Conditions with a presumed functional cause dominate the spectrum of gastroenterologic disorders in outpatient care. In Sweden, the clinical diagnosis "gastritis," which is equivalent to nonulcer dyspepsia, ranks fourth among all diagnoses in primary care,...

Since the recognition of the epidemic of the acquired immunodeficiency syndrome (AIDS) in 1981, several populations have been described that are at increased risk of infection with the human T-cell lymphotropic virus Type III/lymphadenopathy-associated ...

Newer Phosphodiesterase Inhibitors

Among the most promising recent developments in positive inotropic agents has been the description of a class of drugs that have both potent positive inotropic and vasodilatory effects (Table 1). Initial reports have ...

Most of our knowledge about the medical implications of viral disease comes from studies of acute viral infections.^{1 2 3} As a result of such studies, we now understand the clinical courses and pathogenic mechanisms of acute infections, and attempts to ...

Presentation of Case

A 64-year-old woman was admitted to the hospital because of a left hilar mass.

She was well until 15 years earlier, when a routine x-ray film of the chest was reported to show a left hilar mass that was believed to represent enlarged ...

The "fatty heart" (cor adiposum or adipositas cordis) was a very fashionable disease in the last century, and much ink was wasted on this topic in the textbooks of Covisart, Laennec, Stokes, Rokitansky, and others. Ever since Senac¹ described a patient ...

The epidemic of acquired immunodeficiency syndrome (AIDS) has become an epidemic of fear.¹ Although our understanding of the disease has been progressing rapidly, the new knowledge has often produced more public concern than relief. The identification of ...

To the Editor: There are serious flaws in using an epidemiologic study of the sort described by Buehler et al. (July 25 issue)¹ to aid a criminal investigation of possible murder.

First, Rothman² draws a parallel between John Snow's investigation of a ...

To the Editor: We recently transplanted allogeneic bone marrow in a 16-month-old child with Pompé's disease. She had had feeding difficulties and hypotonia since birth. At eight months she had hypotonia, hepatomegaly, and cardiomegaly with elevated ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Intravenous gamma globulins prepared by means of Cohn fractionation have been reported to transmit non-A, non-B hepatitis viruses,^{1 2 3} suggesting that the alcohol concentration, pH, and temperature used in this process do not completely ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The numerous hazards of motorcycle riding are well known, as are the dangers of picking up hitchhikers. The two in combination can be particularly injurious, as we report here.

A 17-year-old boy was referred to our center in June of 1985 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This appears to be the fourth recent textbook devoted to cardiovascular Doppler studies. It is also the longest: 522 pages. It is organized into seven sections: "Fundamentals and Equipment," "Doppler Examination," "Acquired Heart Disease," "Congenital ...

No extract is available for articles shorter than 400 words.

This book summarizes the development over the past 30 years of methods for assessing cerebral blood flow and metabolism. It concentrates on radionuclide methods rather than the conventional brain scanning. There are 18 chapters divided into sections ...

Advances in central nervous system imaging are familiar to many physicians and to the public, but often with limited appreciation of the incredible improvement in anatomical imaging they represent. These advances include computed axial tomography (CAT) ...

This book is an outgrowth of Gofman's monumental work Radiation and Human Health (San Francisco: Sierra Club Books, 1981). It is divided into 22 chapters, including tables based on the authors' data on the risks of future leukemia and cancer resulting ...

No extract is available for articles shorter than 400 words.

Biomédical Science

Adenosine Deaminase in Disorders of Purine Metabolism and in Immune Deficiency. (Annals of the New York Academy of Sciences. Vol. 451.) Edited by George L. Tritsch. 345 pp., illustrated. New York, New York Academy of Sciences, 1985.

...

GENERAL PEDIATRICS AND FAMILY PRACTICE

A course entitled "Third Annual Review & Update — General Pediatrics and Family Practice" will be held at the Royal Waikoloa Hotel in Kona, Hawaii, February 26–March 5. The fee is $400.

Contact Marge Adey, Ctr. for ...