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June 26, 1986  Vol. 314 No. 26

Original Articles
1653-1656

THE perfluorochemical emulsion Fluosol-DA, 20 percent, is an acellular oxygen carrier that has been under investigation for use in acutely anemic patients who refuse blood transfusions.1 2 3 4 5 Numerous laboratory studies have documented that Fluosol-DA ...

1657-1664

IN treating patients with hypertension, physicians who are successful in controlling blood pressure may be unaware of the negative effect that antihypertensive drugs can have on the quality of life1 2 3 4 5 — on the physical state, emotional well-being, ...

1665-1669

STREPTOCOCCI of Lancefield group B are the most common cause of neonatal sepsis in the United States.1 During the past decade, the incidence of early-onset group B streptococcal disease (two to three cases per 1000 live births) has been at least 20-fold ...

Mechanisms of Disease
1670-1676

    ISCHEMIC diseases of the heart, kidney, and brain continue to be the primary causes of mortality and morbidity in the United States and other Western industrialized nations. The magnitude of the problem has stimulated much research directed at identifying ...

    Medical Progress
    1676-1686

      OSTEOPOROSIS is an enormous public health problem, responsible for at least 1.2 million fractures in the United States each year. The sites of these fractures are the vertebrae in 538,000 cases, the hip in 227,000, the distal forearm (Colles' fracture) in ...

      Medical Intelligence
      1686-1689

        CHEMOTHERAPY of metastatic or otherwise inoperable glucagon-producing islet-cell tumors (glucagonomas) has been unsatisfactory. The agents most frequently used, streptozocin and dacarbazine, are rather toxic and often not very effective.1 Recently a long-...

        Case Records of the Massachusetts General Hospital
        1689-1700

        Presentation of Case

        A 24-year-old woman was admitted to the hospital because of progressive deterioration in her mental status.

        The patient was born legally blind in the left eye because of a central chorioretinal lesion that was believed typical of ...

        Editorials
        1701-1702

        Hypertension is a major public health problem, afflicting at least 35 million people in the United States. Impressive advances in the pharmacotherapy of hypertension have been made over the past three decades. More than 10 million hypertensive patients ...

        1702-1704

        Despite notable advances in the treatment of sick newborn infants, bacterial infections during the first week of life continue to claim hundreds of lives. The most common of these early-onset neonatal infections is caused by streptococci of Lancefield ...

        Correspondence
        1704-1706

        No extract is available for articles shorter than 400 words.

        1706-1707

        No extract is available for articles shorter than 400 words.

        1707-1710

        To the Editor: This letter addresses only the first paragraph of the paper by Schneider et al., "Recommended Dietary Allowances and the Health of the Elderly," in the January 16 issue.* It refers to a draft document on recommended dietary allowances (...

        1710

        To the Editor: A woman from a small Vermont town testified recently before the governor's task force on hunger that she had been buying groceries for an elderly woman living alone whose shopping list often included canned pet food of unspecified brands. ...

        1710-1711

        No extract is available for articles shorter than 400 words.

        1711

        No extract is available for articles shorter than 400 words.

        1711

        No extract is available for articles shorter than 400 words.

        1711-1712

        To the Editor: The cholinergic hypothesis of Alzheimer's disease, discussed by Francis et al. in the July 4 issue,1 has shortcomings: (1) Cholinergic replacement therapy has been unsuccessful, (2) hypometabolism and cholinergic denervation do not occur ...

        1712-1713

        No extract is available for articles shorter than 400 words.

        Occasional Notes
        1713-1715

        WE middle-aged and older physicians are smug about our house-staff days — the days when medical giants roamed the hospital halls day and night. We prepared and stained our own blood smears, performed white-cell counts and differentials, actually looked ...

        Book Reviews
        1715

        No extract is available for articles shorter than 400 words.

        1715

        The contributing authors of this book, many of the outstanding investigators in the field of sudden cardiac death, have provided a useful and current summary of the problems involved.

        The title raises certain semantic questions about the definitions of "...

        1715-1716

        One of the most striking changes in medical practice over the past two decades has been the enormous increase in the fraction of hospitalized patients treated in intensive care units. Concentration of critically ill patients in designated areas is now ...

        1716

        Here, the editor has put together a useful book that addresses an intriguing question: Can clinical problem solving be taught, or is it rather the result of some inexpressible intuitive process? He comes down squarely on the side of those who believe that ...

        1716

        No extract is available for articles shorter than 400 words.

        1717

        Recent books on nutrition seem to fall into two categories. The most numerous are the clinical treatises with some biochemistry. This book falls into the second category, which consists of books whose content is largely biochemical, with minimal clinical ...

        1717

        No extract is available for articles shorter than 400 words.

        1717-1718

        As the authors of this superbly organized book note in their preface, physicians frequently see patients with a dermatitis that is readily traceable to contact with a plant, but then an impasse develops because neither physician nor patient can identify ...

        1718

        This new edition of The Normal Lung appears 10 years after the first, and it is clearly welcome. It is written in an authoritative style that shows Murray's touch from the first to the last of the 14 chapters. In his eloquent fashion, he teaches ...

        Books Received
        1718-1719

        Biomedical Science

        Basic Medical Microbiology. Third edition. By Robert F. Boyd and Bryan G. Hoerl. 964 pp., illustrated. Boston, Little, Brown, 1986. $33.

        Biology of the Integument. Vol. 2. Vertebrates. Edited by J. Bereiter-Hahn, A.G. Matoltsy, and K. ...

        Notices
        1720

        PLASTIC SURGERY

        The Annual National Congress of the Association of Plastic and Reconstructive Surgeons of South Africa will be held at the Sandton Holiday Inn, Johannesburg, South Africa, August 28–30.

        Contact Mr. S.A. Braun, P.O. Box 52828, Saxonwold ...

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