THE short-term or long-term prognosis after acute myocardial infarction is related to the amount of myocardium damaged and thus to the extent of left ventricular dysfunction.¹ The most effective way to limit myocardial necrosis in evolving myocardial ...

PATIENTS with a myelodysplastic syndrome have a variable clinical course. Poor survival has been related to a number of factors, including the percentage of blast cells in the bone marrow,¹ abnormal proliferation of granulocyte progenitors,² and the ...

THE human major histocompatibility complex on the short arm of chromosome 6 includes the genes coding for the determinants of the HLA-A, B, C, and D regions, as well as the complement proteins factor B, C2, C4A, and C4B.^{1 , 2} Alleles at these loci ...

WE have previously shown that administration of estrogen to normal postmenopausal women reduces both the plasma calcium concentration and the urinary calcium excretion within three weeks.¹ These effects result from a decrease in the rate of bone ...

SOME patients with severe chronic airflow obstruction report that they have disabling dyspnea when performing seemingly trivial upper-extremity activities, such as combing their hair or brushing their teeth, although they are capable of more demanding ...

AS the pressure to control health care costs has grown, third-party payers and others have increasingly undertaken to assess the merits of procedures and equipment used in patient care. Interest in such assessment is strong in both the public and private ...

AUTONOMIC disorders are usually characterized by widespread abnormalities in both the sympathetic and the parasympathetic systems; this is true whether the autonomic disorder is associated with central neurologic deficits or is confined to the peripheral ...

Presentation of Case

First admission. A 55-year-old right-handed woman was admitted to the hospital because of blurred vision.

She was well until 28 months earlier, when she began to experience blurring of vision in both eyes. An ophthalmologist found no ...

Most people can agree that primary hyperparathyroidism is not uncommon,¹ especially among postmenopausal women,^{1 , 2} and that it is best treated with curative parathyroidectomy when complicated by renal stones, bone disease, calcium levels above 12 mg per ...

Exercise capacity is normally limited by the maximal rate of oxygen transport to the mitochondria of the exercising muscles. The limiting symptoms are skeletal-muscle fatigue and discomfort caused by local anaerobic metabolism and lactic acid ...

No extract is available for articles shorter than 400 words.

To the Editor: Enlarged intrathoracic lymph nodes are a prominent feature of sarcoidosis. In most cases, there is complete roentgenographic resolution after a variable period. The nodes may continue to be enlarged for several years, or they may remit and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Vitamin D–binding protein is present on the majority of normal human peripheral-blood B lymphocytes.¹ Although the function of this protein is not known, it may be involved in linkage between surface immunoglobulin and actin² and may also ...

To the Editor: Myers and co-workers have attempted to study the pathogenesis of human acute renal failure by an imaginative use of indirect techniques, as reported in the Journal (Jan. 9 issue) and elsewhere.^{1 2 3 4 5 6} However, we find several problems ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Most large cities in the United States now have magnetic resonance imagers in operation. This letter describes a potentially fatal accident involving such an imager. On December 15, 1985, technical engineers were installing a 1.5-tesla ...

To the Editor: The ingestion or mouthing of some toads is well known by veterinarians to cause severe intoxication, often with fatal outcomes. Dogs and cats become paralyzed and die in many cases of toad ingestion. Salivation, cyanosis, and convulsive ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Nearly a decade in preparation, this handsome, apparently exhaustive new dictionary was compiled with the help of 81 advisers, 10 co-advisers, 90 contributors, and an 8-member panel on preferred usage in various parts of the world. It contains 151,000 ...

No extract is available for articles shorter than 400 words.

This is a propitious time for the publication of a book on genetics and cancer. Recent advances in molecular genetics have led to fundamentally new understandings of the nature of oncogenesis. Although most physicians may be generally familiar with the ...

No extract is available for articles shorter than 400 words.

This book fills a niche between the encyclopedic and basic science orientation of Field's Virology (New York: Raven Press, 1985; reviewed in the Journal 1986; 314:63) and the more superficial treatment provided by most internal medicine textbooks. The ...

A major consideration in evaluating the suitability of a gross anatomy textbook is assessing whether students will read it. Course directors face the dilemma of choosing a basic detailed anatomy book that students may not read or a superficial textbook ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This slim book attempts to cover bone biology at a level understandable to students of physical anthropology, forensic pathology, paleontology, and biomechanics. The first part of the book concentrates on bone structure, bone growth, the mechanics of ...

EPIDEMIOLOGY

The Johns Hopkins Graduate Summer Program in Epidemiology — 1986 will be held in Baltimore, June 23–July 12.

Contact Steven G. Warm, Graduate Summer Program in Epidemiology, 615 N. Wolfe St., Baltimore, MD 21205; or call (301) 955–7158.

...

No extract is available for articles shorter than 400 words.

Health care is undergoing a major and often troubling transition. The once dominant structure of community not-for-profit hospitals and their independent, largely solo-practitioner medical staffs has undergone many organizational transformations. Multi-...