THE depressed phase of primary affective disorder is frequently associated with sustained hypercortisolism^{1 , 2} (which is sometimes of sufficient magnitude to be termed a pseudo-Cushing's state), and patients with Cushing's disease often have signs of ...

ANOREXIA nervosa is thought to be a psychiatric syndrome characterized by a striking increase in physical activity and a marked diminution of food intake in the obsessive pursuit of thinness.^{1 2 3} The course of this disorder can be erratic, with periods ...

IDIOPATHIC pulmonary fibrosis is a chronic, progressive, usually fatal interstitial lung disorder characterized by inflammation and fibrosis of the alveolar walls.^{1 2 3 4 5 6 7 8 9} Although its cause is unknown, a great deal is known about the ...

PROLONGED hypoestrogenism is a recognized complication of dieting, weight loss, and physical training in young women. A high incidence of delayed menarche, secondary amenorrhea, and irregular menstrual periods has been observed in young ballet dancers.¹ ...

IN 1890, artificial insemination was first successfully accomplished in the United States.¹ Since then, about 500,000 children in this country have been born to women fertilized by this method, and the rate of use of the procedure has risen steadily.^{2 , 3} ...

DURING the past decade a wealth of information concerning the pathogenesis of Type I diabetes has become available. Two spontaneous animal models of the disease have been discovered and characterized (the Biobreeding rat and the non-obese diabetic mouse); ...

Presentation of Case

A 68-year-old man was admitted to the hospital because of diarrhea and chylous ascites.

He was well until two years earlier, when diarrhea began and gradually worsened, with the passage of watery, brown, foul stools that floated in ...

If cost-containment measures, such as the use of Medicare's diagnosis-related groups (DRGs), involved trimming only unnecessary health care services from public budgets, they would pose no moral problems. Instead, such measures lead physicians and ...

Adolescent idiopathic scoliosis is a common problem; its prevalence in the general population is about 1.8 percent, if minor curvatures of 5 to 10 degrees are included. Progressive scoliosis and scoliosis that requires treatment are much more common in ...

The United States and Great Britain have often been called two countries divided by a common language. In the field of medicine, common language facilitates comparisons, but it can obscure basic value differences as well. Henry Aaron, Ph.D., and William ...

To the Editor: In a letter in the January 16 issue,¹ Dr. Edelbaum noted the rarity of reports of the acquired immunodeficiency syndrome (AIDS) in patients on hemodialysis. He speculated about the possible protective effect of renal failure. I would ...

No extract is available for articles shorter than 400 words.

To the Editor: The presence of antibodies to HTLV-III has been reported in banked serum samples obtained from parenteral drug abusers as early as 1979.¹ Whether this virus was introduced into this population earlier is subject to speculation.

We recently ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The plasma-derived hepatitis B vaccine (Heptavax B, Merck Sharp & Dohme) is currently recommended for medical personnel at high risk of acquiring hepatitis B.¹ This recommendation is based in part on field trials that showed the vaccine to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

There are many textbooks and reference sources available that deal with basic pharmacology or therapeutics. This book is unique in that it focuses concisely on the critical evaluation of drug treatments. It provides an overview of commonly used ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Specialists in addiction and general clinicians debate hotly the relation between psychopathology and substance abuse. Positions tend to polarize, with one camp supporting the "disease concept" and holding that alcoholism causes psychopathology, and the ...

Americans have always enjoyed their drink. Throughout our nation's history, alcohol consumption has been high. In 1825, for example, the annual per capita consumption of alcohol by adults was about 7 gallons. After the Civil War, American tastes ran more ...

Here is an interesting and thoughtful book that does a favor for all those who would like to have the stereotype of heroin addiction brought into line with clinical reality. It is a result of a study of 124 heroin addicts, from the ghettos of four ...

No extract is available for articles shorter than 400 words.