Aseries of recent studies have demonstrated the capacity of intranasally administered interferon in an appropriate dosage to inhibit the acquisition of rhinovirus infection.^{1 2 3 4 5 6} However, despite repeated confirmation of the virologic efficacy of ...

Prophylactic intranasal administration of either interferon derived from human leukocytes or recombinant DNA–produced alpha₂-interferon is effective in preventing experimental rhinovirus^{1 2 3 4} and coronavirus infection.⁵ Community-based field studies in ...

The α-globin-gene cluster is normally composed of an embryonic zeta(ζ)-globin gene, an inactive pseudo-ζ-globin (ψζ) gene, an inactive pseudo-α-globin (ψα) gene, and two α-globin genes. These five gene loci are closely linked within about 30 kb on the ...

Tobacco smokers generally weigh less than nonsmokers,^{1 2 3} and this difference increases with the duration of smoking and with age.^{2 , 3} Moreover, when people stop smoking, they tend to gain weight.^{1 , 2 , 4 , 5} The question whether smoking influences ...

Serologic tests are used routinely for the diagnosis of histoplasmosis. However, the usefulness of these tests is hampered by the high frequency of false positive¹ and false negative reactions.^{2 , 3} Furthermore, since the antibody levels may remain ...

Hospital management companies are big businesses that are growing bigger. In the past decade, although the total number of hospitals in the United States has remained about the same, the proportion of hospitals that are affiliated with investor-owned ...

Classic (Oliguric) Acute Renal Failure

The syndrome of acute renal failure was first recognized during World War II. The sudden but ultimately reversible depression of renal function observed initially in victims of crush injuries,¹ and later in ...

Presentation of Case

A 67-year-old man was admitted to the hospital because of progressive weakness of the legs.

Ten years earlier, after a fall, x-ray films of the pelvis showed Paget's disease. The patient was free of symptoms until six years before ...

So far, common colds have not yielded to advances in modern science. Nothing we do seems to prevent their regular occurrence or alleviate the annoying symptoms — and we try hard. The 1985 over-the-counter market for common cold treatments is estimated to ...

In the management of a suspected fungal infection, no diagnostic test is superior to the isolation of the causative agent from a relevant clinical specimen, or to its unequivocal physical identification in a histopathological setting of tissue invasion. ...

To the Editor: The acquired immunodeficiency syndrome (AIDS) is etiologically linked to human T-cell lymphotropic virus Type III (HTLV-III). Intravenous drug use is the primary known risk factor in 17 percent of U.S. cases of AIDS.¹ We now report that ...

To the Editor: The recommendations of the Public Health Service for screening donated blood for antibodies to the HTLV-III virus have recently been implemented.^{1 , 2} The financial and psychosocial repercussions of widespread testing of asymptomatic ...

No extract is available for articles shorter than 400 words.

To the Editor: We reported¹ a high risk of leukemia and preleukemia among 2067 patients given adjuvant semustine (methyl-CCNU) and fluorouracil in any of nine randomized clinical trials for gastrointestinal cancer (relative risk, 16; incidence rate, 2.4 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Phototherapy of neonatal jaundice depends for its success on photochemical reactions of bilirubin within the baby.¹ The chance observation of an apparent bilirubin photoproduct in a healthy adult who had just returned from a run suggested ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I suggest that the word "abstract" be reserved for descriptions of studies that have passed editorial review and whose full text is available to readers. The term "hypothesis under study" (or HUSsy) could be used for prepublication ...

This is an amazing book that brings together an enormous wealth of information on technology assessment in a concise and readable fashion. Although based on experience in the United States, it deals with a variety of technology-related debates. Aspects of ...

Much of what is written by professionals is comprehensible only to fellow professionals. The term "professional literature" denotes that which is published by doctors for doctors, by lawyers for lawyers, and so on. Such writing is often opaque to anyone ...

This book is an outgrowth of a project on "Social Controls and the Medical Profession," that was initiated by Medicine in the Public Interest and supported by funds from the National Science Foundation and the National Endowment for the Humanities. The ...

Here is a detailed exploration of the multiplicity of tasks that health workers must perform as they treat and manage illness. Some of these tasks, such as ensuring the comfort and safety of patients, are as old as the practice of medicine. However, the ...

This well-documented, frequently entertaining, and lucidly written book outlines the history of American medical education. Beginning with the proprietary medical-school system of the mid-19th century, the author explores the major historical trends that ...

What are the boundaries of inquiry for "quality assessment" in health care? Surely, they must include attempts to judge whether one doctor, hospital, or system is better than another in accomplishing the goals of health care. But does it also include ...

As an academic discipline, bioethics is enjoying a heyday. Virtually every university offers a bioethics course, conferences on the subject are convened often, and publishers offer a spate of bioethics books.

Weiss' book joins a growing number of ...

Physical torture as a systematic practice of government is commonplace throughout most of the world today. Its more sophisticated analogue — the use of psychiatric institutions as political prisons, where torture is conducted in the form of psychiatric "...

BIOMEDICAL SCIENCE

Biomaterials in Artificial Organs. Edited by John P. Paul, James M. Courtney, John D.S. Gaylor, and Thomas Gilchrist. 370 pp., illustrated. Deerfield Beach, Fla., VCH, 1985. $74.

Brain Plasticity, Learning, and Memory. (Advances in ...

NUCLEAR MAGNETIC RESONANCE

The fourth annual meeting of the European Workshop on Nuclear Magnetic Resonance in Medicine will be held at the Centre de Congres Auditorium in Monte Carlo, Monaco, March 12–15.

Contact Dr. Robert N. Muller, State University of ...

Before the identification of the human T-cell lymphotropic virus Type III/lymphadenopathy-associated virus (HTLV-III/LAV) as the cause of the acquired immunodeficiency syndrome (AIDS), the clinical recognition of this disease depended on the occurrence of ...