RETINOBLASTOMA is one of a group of childhood cancers to which predisposition can be inherited as an autosomal dominant trait.¹ The disease can arise after inheritance of a predisposing germ-line mutation from an affected parent (about 10 percent of cases)...

BACTERIAL adherence plays an important part in the pathogenesis of community-acquired urinary tract infections. A growing body of evidence suggests that differences in the ability of host epithelial cells to bind bacteria with specific adhesins influence ...

UNSTABLE angina is a common ischemic condition characterized by symptoms of recent onset, a crescendo pattern, or the occurrence of symptoms at rest. Patients with angina at rest treated medically have the poorest short-term and long-term prognosis, and ...

CYCLOSPORINE has been reported to be a powerful immunosuppressive agent¹ that works primarily by inhibiting T-cell function.² Results from both controlled and uncontrolled studies indicate that cyclosporine is a useful immunosuppressant in transplantation ...

THE primary purpose of this article is to assess the overall progress against cancer during the years 1950 to 1982, the most recent year for which reliable data are available. During this time there was very rapid and extensive growth of private and ...

EXTENSIVE phlebotomy for diagnostic testing in neonates regularly causes anemia and is one of the most common reasons for transfusion in that population.^{1 2 3} Although the excessive use of laboratory tests in adults has been reviewed from the standpoint ...

THE production of antiplatelet antibodies and removal of IgG-coated platelets by the mononuclear phagocyte system play an important part in the pathogenesis of immune thrombocytopenic purpura. The coating of platelets with immunoglobulin results in their ...

Presentation of Case

A 44-year-old woman was admitted to the hospital because of chest pain.

She was well until the afternoon before admission, when she was informed that her 17-year-old son had committed suicide by hanging earlier in the day. Half an ...

Retinoblastoma, a tumor of the eye that occurs in approximately 1 in 20,000 live-born infants, has proved to be a valuable model for the study of the roles of single genes in the causation of cancer. In this issue of the Journal, Cavenee and colleagues ...

The only two mammals to remove blood regularly from other mammals are vampire bats (subfamily, Desmodontinae) and humans. Vampires, dead people who rise from their graves at night to nourish themselves on the blood of the living (that is, Dracula and his ...

Abkowitz — Herbert Abkowitz, M.D., of Stoneham, died on January 23 at the age of 77.

Dr. Abkowitz received his degree from Kansas City University of Physicians and Surgeons in 1933. He was a member of the American Academy of General Practice.

Agranat — ...

To the Editor: In answer to the letter by Atkinson et al. (July 18 issue),¹ we certainly agree that immunodeficiency observed after bone marrow transplantation is not always related to the acquired immunodeficiency syndrome (AIDS). Nevertheless, we would ...

No extract is available for articles shorter than 400 words.

To the Editor: The morbidity and mortality associated with major eating disorders continues to be a matter of appropriate concern to physicians and nutrition scientists. The role of the cardiovascular system in this setting has been of particular ...

No extract is available for articles shorter than 400 words.

To the Editor: Hepatitis B exposure and carrier rates have been studied extensively in institutions for the mentally retarded and in prisons, but there is a paucity of such information about the mentally ill.¹ Although the risk of hepatitis B in the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A deficiency of uridine diphosphate galactose 4-epimerase can cause a severe form of galactosemia in humans.^{1 2 3} The 4-epimerase enzyme normally catalyzes the reversible isomerization of uridine diphosphate galactose and uridine ...

To the Editor: The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is characterized by hyponatremia primarily due to water retention and is associated with natriuresis that is inappropriate to the low plasma sodium concentration.¹ ...

To the Editor: Articles such as that of Kircher et al. (Nov. 14 issue)¹ reaffirming the value of the autopsy are important and necessary in helping to maintain the autopsy as an important exercise in the clinical practice of medicine. However, in his ...

No extract is available for articles shorter than 400 words.

This delightful book, intended for persons interested in aging, addresses issues of human productivity as explored by 32 scholars who represented 15 countries during the first program on aging at the Salzburg seminar. Moving beyond the usual concepts of ...

Many of the contemporary great plagues are self-induced and can be altered only by behavioral changes. Examples include accidents on the road or in the home, cigarette smoking, drug and alcohol abuse, environmental pollution, overpopulation, obesity, ...

No extract is available for articles shorter than 400 words.

Medicine is a regulated industry, and neither decrying nor ignoring that fact will change it. Understanding the reasons for and the nature of the regulation, however, may go a long way toward reducing physicians' frustration and increasing their ...

What is the real value of an ounce of prevention? In this painstaking analysis, Louise Russell shreds the myth that an ounce of prevention equals a pound of cure with a high-technology paper shredder. From the myth, she retrieves what she perceives as the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is a timely collection of essays that explore the experiences of women as providers and recipients of health care in the United States, Canada, and Great Britain. Combining feminist scholarship with a call to activism, the authors examine women's ...

Biomedical Science

The Biophysical Basis of Excitability. By Hugo Gil Ferreira and Michael W. Marshall. 484 pp., illustrated. New York, Cambridge University Press, 1985. $80.

Design and Performance of Muscular Systems. (Journal of Experimental Biology. ...

CALL FOR PAPERS

Abstracts are now being accepted for the fifth international Conference on Psychonephrology, to be held at the New York Hilton Hotel, October 17–19. The deadline for receipt of abstracts is July 1.

Contact Dr. Norman B. Levy, Liaison ...

IN 1982, California terminated Medi-Cal benefits for the state's 270,000 medically indigent adults and transferred responsibility for their care to the county system. A medically indigent adult is a person who previously received Medi-Cal benefits because ...