HIGH-DOSE chemoirradiation therapy and transplantation of marrow from HLA-identical siblings have been used successfully to treat patients with acute nonlymphoblastic leukemia in the first remission^{1 2 3 4 5 6} or with chronic myelocytic leukemia in the ...

alpha1-antitrypsin, a glycoprotein synthesized in the liver, is the main protease inhibitor in human serum. Its most important biologic function is to bind and inactivate leukocyte elastase. The biosynthesis of α₁-antitrypsin is controlled by a pair of ...

TRAUMATIC transection of the lower segments of the cervical cord produces paralysis of all the well-recognized muscles of expiration, such as those in the anterolateral wall of the abdomen and the expiratory intercostals. As a result, the cough is ...

HIGH levels of plasma cholesterol constitute a risk factor for coronary heart disease,^{1 2 3} and a dietary approach to preventing such disease by reducing plasma cholesterol is widely advocated.^{4 , 5} The diet usually recommended for lowering cholesterol is ...

The Clinical Spectrum of HSV Infections

Herpes simplex virus (HSV) has been isolated from nearly all visceral and mucocutaneous sites. The clinical manifestations and course of HSV infections depend on the anatomic site of the infection, the age and ...

IT is generally accepted that red cells possess enzymatic reducing mechanisms that maintain hemoglobin in its active state.^{1 , 2} It is also well established that the reduction is dependent on the regeneration of reduced pyridine nucleotides.^{3 4 5} Treating ...

EMPHYSEMA is a chronic disorder of the lower respiratory tract characterized by enlargement of the air space distal to the terminal bronchioles resulting from destruction of the alveolar walls.^{1 , 2} In the United States and Europe, approximately 2 percent ...

Presentation of Case

A 34-year-old woman was admitted to the hospital because of episodic right facial numbness.

She was well until one year earlier, when she experienced the first of three episodes of numbness that affected the right upper and lower ...

THE inspiratory muscles are the only skeletal muscles vital to life, and the commonest threat to life in neuromuscular disorders is respiratory failure. Therefore, in patients with neuromuscular disorders leading to weakness, it is critically important to ...

In Eleven Blue Men,¹ a medical detective figures out that a group of derelicts have become cyanotic because they have methemoglobinemia — the iron in at least 10 percent of their hemoglobin molecules has become oxidized, from Fe⁺⁺ to Fe⁺⁺⁺. Furthermore, ...

alpha1-antitrypsin deficiency (also known as α₁-protease-inhibitor deficiency) is a genetic disorder that has become known to physicians in most disciplines and to the lay public. Some of the genetic types (known as Pi types, including Z and S) cause ...

IN this essay I shall try to summarize in mid-course the status of a unique series of events in human history, which involves virtually all facets of modern knowledge but is usually referred to simply as the acquired immunodeficiency syndrome (AIDS) ...

To the Editor: Dr. Kraus et al. are to be commended for their investigation of the use of atenolol in patients with alcohol withdrawal (Oct. 10 issue).¹ Their article raises several interesting concerns. How was informed consent obtained in this group of ...

No extract is available for articles shorter than 400 words.

To the Editor: The Medical Progress article on hepatic encephalopathy by Fraser and Arieff (Oct. 3 issue)¹ contains several errors that could lead to mistakes of understanding or treatment.

It states, "After ammonia is generated [in the gut], it is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

At first, the world was startled to learn that a five-year-old effort by physicians to help prevent nuclear war would be awarded the 1985 Nobel Peace Prize. Surprise rapidly turned to criticism, however, as our organization, International Physicians for ...

No extract is available for articles shorter than 400 words.

Eclectic, multimodal approaches are becoming dominant in American psychiatry. Practitioners frequently combine behavioral, psychodynamic, and pharmacologic treatments. Various theories of the causes of major psychiatric disorders are often seen as ...

When the third edition of the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-III) was introduced in 1980, the question often heard at the time was "Now that I have a diagnosis, what do I do with it?" Since the manual was by ...

This book consists of 16 chapters under three headings. Part I describes biologic factors in the development of schizophrenia. Part II takes up clinical considerations, and Part III discusses current treatment issues.

Because of the topic addressed, this ...

Psychoanalysis has undergone a steady, dramatic evolution from a single theory of behavior and therapeutic technique to a field with a wide variety of theoretical emphases and therapeutic styles. Although many factors have been responsible for this growth,...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Biotechnological Processes. Vol. 5. Edited by Avshalom Mizrahi and Antonius L. van Wezel. 312 pp., illustrated. New York, Alan R. Liss, 1985. $78.

Amino Acids. (Neuromethods, Series I. Vol. 3.) Edited by Alan A. Boulton, ...

CLINICAL NUTRITION

The American Society for Clinical Nutrition will sponsor a postgraduate course in clinical nutrition at the Sheraton Washington Hotel in Washington, D.C., April 28–29.

Contact the American Society for Clinical Nutrition, 9650 Rockville ...

No extract is available for articles shorter than 400 words.