The gallbladder bile of patients with cholesterol gallstones is generally supersaturated with cholesterol — i.e., it contains more cholesterol than can be rendered soluble by the available bile acids and phospholipids.¹ Supersaturation of bile, however, ...

Atopic dermatitis, a common chronic skin disease associated with intense pruritus and lichenification, has no specific cutaneous signs, no known distinctive histologic features, and no characteristic laboratory findings.^{1 , 2} It is frequently associated ...

Acute lymphoblastic leukemia (ALL) is a heterogeneous group of disorders that lead to clonal expansion of the precursors of B or T lymphocytes. Progress in therapy for ALL has allowed clinicians to induce remission in nearly all patients with this ...

Phenacetin was introduced into therapy in 1887 and has been widely used in analgesic mixtures. In the United States it has gradually been withdrawn from the market because of evidence of an association with a distinct form of chronic interstitial ...

Anorexia nervosa is a syndrome characterized by extreme weight loss, body-image disturbance, and an intense fear of becoming obese. Bulimia is a syndrome distinct from anorexia nervosa and is characterized by secretive binge-eating episodes followed by ...

Although both maternal and cardiovascular mortality have declined during the past decade, the apparent prevalence of cardiovascular disorders in pregnant patients has remained relatively constant because of three medical advances. These include more ...

The Kasabach-Merritt syndrome is characterized by thrombocytopenia associated with solitary or multiple hemangiomas.¹ Coagulation studies in patients with this disease frequently reveal a profile similar to that of disseminated intravascular coagulation.² ...

CASE 31–1985

Presentation of Case

A 43-year-old man was referred to the hospital because of fever of unknown origin.

There was a history of coarctation of the aorta, with surgical repair at the age of 12 years; an appendectomy was performed two years ...

The push is clearly on to make the delivery of health services more businesslike. National concern about the cost of health care and competition for scarce resources have led both health care institutions and providers to become preoccupied with altering ...

With the development of new surgical techniques and immunosuppressive drugs, the demand for organs and donors has outpaced the supply, despite widespread legal recognition of brain death.^{1 2 3 4 5 6} According to a 1982 estimate, "out of some 20,000 ...

To the Editor: The neurologic complications of the acquired immunodeficiency syndrome (AIDS) have included opportunistic infections involving the central nervous system,¹ a recently described vacuolar myelopathy,^{2 , 3} and a subacute encephalopathy.⁴ In ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Stimulatory effects of the endogenous opioid system on eating behavior have been postulated for both lower animals^{1 , 2} and human beings.³ Naloxone, an opiate antagonist, has been shown to block eating behavior induced in animals by stress^...

To the Editor: Williams et al. (March 28 issue)¹ demonstrate that the rise in the plasma potassium level that occurs during exercise is associated with increased plasma catecholamine levels. This elevation of the plasma potassium level is enhanced by β-...

To the Editor: In the section of her article devoted to pregnancy in renal transplant recipients (March 28 issue), Dr. Hou claims that risks to the fetus from immunosuppressive therapy are small.¹ No increased incidence of birth defects has been found in ...

To the Editor: We want to focus attention on the accidental death of an infant at the National Institutes of Health due to the inadvertent administration of 5 per cent sodium chloride.

A 20-month-old infant was admitted to the Clinical Center with the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Traditionally, the treatment of pineal tumors is conservative and based on the use of radiation therapy and a shunt to diminish cerebrospinal fluid pressure. This therapeutic strategy often gives the patient five years of a symptom-free life, but no cure. ...

We now have two more books on the pituitary, in addition to seven on pituitary disease that have been published in the past seven years. There are also some devoted to one disease (e.g., acromegaly), one discipline (e.g., pathology or neurosurgery), or ...

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

INSTITUTE FOR HEALTH POLICY ANALYSIS

The newly formed International Society of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.