ANTINEOPLASTIC drugs as a class include chemically unrelated agents that can inhibit the growth of tumors by disrupting cell growth and killing actively growing cells.¹ This family of drugs includes alkylating agents (e.g., cyclophosphamide), ...

IN 1958 Cheek and Perry¹ described a male infant in whom renal salt wasting was associated with normal renal and adrenal function. The condition was corrected by sodium chloride supplementation but was refractory to exogenous mineralocorticoid without ...

FIVE enzymatic reactions are involved in the synthesis of testosterone from cholesterol, and five distinct genetic defects of impaired testosterone biosynthesis that result in incomplete masculinization of the male fetus have been described.¹ Cortisol ...

THE first extracranial-to-intracranial (EC-IC) arterial anastomosis was performed in 1967,¹ and during the next decade the technique was widely applied. In order to test its ability to reduce the rate of subsequent stroke among patients with symptomatic ...

OVER the past decade, the amount spent on hospital care in the United States has almost quadrupled, from $34.9 billion in 1972 to $135.5 billion in 1982.¹ In an effort to determine what has contributed to this rapid rise in costs, health economists have ...

PULMONARY congestion in a patient with acute myocardial infarction is a poor prognostic sign,^{1 2 3} even if left ventricular ejection fraction measured at least six days after the acute event is normal or nearly so.^{3 , 4} Acute pulmonary edema accompanying ...

Presentation of Case

First admission. A 56-year-old man was admitted to the hospital because of chronic liver disease and diabetes mellitus.

There was a history of chronic liver disease of at least 10 years' duration. For about five years the patient was ...

The study by Selevan et al. in this issue of the Journal ¹ provides documentation that nurses exposed to antineoplastic drugs are at risk of adverse effects on reproduction. Thus, an outcome that could be predicted from the vast amount of research on the ...

IN this issue of the Journal, Barnett and his co-workers¹ report the results of a remarkable piece of clinical investigation, comparing in a controlled, prospective study the neurologic effects of surgical extracranial—intracranial arterial bypass (EC—IC ...

Recently, we have been witnessing an outpouring of commentaries and analyses pointing out the conflicting interests that have led to the current health care "crisis" and calling for the articulation of a national policy reconciling these interests.¹ The ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Undue publicity has been given to continuous cervical-cord stimulation by means of extradurally implanted electrodes for the treatment of torsion dystonia. A "case report" of one person said to have generalized dystonia appeared on the ...

To the Editor: Naturally occurring somatostatin has been reported to be useful in correcting the hypotension and flushing seen in patients with the malignant carcinoid syndrome,^{1 , 2} although its practical usefulness has been limited by a very short half-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A great variety of symptoms from the peripheral as well as the central nervous system may occur in infection with the tick-borne spirochete Borrelia burgdorferi, which causes Lyme disease,¹ and related European borrelia strains that ...

No extract is available for articles shorter than 400 words.

To the Editor: I have followed with interest your letters regarding avian attacks on joggers. Such harrassment is known to naturalists, and I have myself been attacked by Australian magpies (gymnorhina spp.), birds whose males commonly pounce on ...

To the Editor: Drs. Jencks and Dobson (June 6 issue)¹ are to be commended for an insightful review of the subject of Medicare physician payment, and especially for their summary of research on physician payment based on diagnosis-related groups (DRGs) ...

To the Editor: Recently, great strides have been made in establishing high-quality treatment services for alcoholism and other drug abuse. Tobacco dependency has remained untouched by this movement. The accessibility and availability of other substance-...

No extract is available for articles shorter than 400 words.

Here is an important contribution to the field of perinatal medicine. It should be in the library of all obstetricians, perinatologists and internists who deal with pregnant women. In its discussion of the medical complications of pregnancy, the book is ...

The first edition of this textbook was published in 1960, and a second edition in 1965; 20 years later the current editors have provided this third edition. They preface this work by stating "... in view of the astounding rate at which our knowledge is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This history of neonatal medical care is a must for anyone who treats the newborn. By tracing the development of neonatology, it teaches us that current theories and therapies are just one stage in the progress of medical knowledge. We see that the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

I liked this book. In it I found echoes of conversations with worried parents on many of the topics illuminated by the authors. The text is clear, informative, and written in excellent "parentese" skillfully translated into "medicalese." The contents ...

The author sets out to determine the effects of legal abortion on maternal and child health statistics. He applies time-series analysis to published rates for abortion-related deaths, non-abortion-related maternal mortality, infant mortality, fetal ...

PLASTIC SURGERY

The Plastic Surgery Educational Foundation and the Jewish Hospital of Cincinnati will sponsor a symposium and workshop entitled "Lasers for the Plastic Surgeon" at the Westin Hotel and the Jewish Hospital in Cincinnati, November 22–24. The ...

Iron deficiency is the most common single nutrient deficiency in the world. Studies in the United States have shown that the prevalence of overt iron-deficiency anemia is 5 to 15 per cent in American infants and children 9 to 36 months old.^{1 2 3} Although ...