ON the basis of marker assays, such as sheep-erythrocyte rosette formation, the presence of surface immunoglobulin, or reactivity to a panel of monoclonal antibodies, childhood acute lymphoblastic leukemia (ALL) is generally subdivided into three types: T-...

PRESCRIBED estrogen use is very common in our society. In the 1970s it was estimated that more than 30 per cent of postmenopausal women in the United States used prescribed estrogen.¹ Many studies have investigated potential detrimental effects of such ...

THE possible role of exogenous estrogens in coronary heart disease has been controversial for decades. The observations that premenopausal women are at lower risk for coronary disease than postmenopausal women and that estrogens favorably influence serum ...

THE heart responds to an augmented workload by increasing its mass. An important component of this process may be increased energy use — i.e., increased turnover of the primary high-energy, phosphate-containing compounds ATP (adenosine triphosphate) and ...

THE results of several controlled clinical trials now suggest that long-term beta-adrenergic blockade reduces total mortality after acute myocardial infarction. In two of the largest studies, sustained therapeutic effects were demonstrated for up to three ...

IN recent years, our understanding of the nature and diversity of viruses causing hepatitis in human beings has been sharply increased.¹ Those agents now include the viruses of hepatitis A (classic short-incubation infectious hepatitis) and hepatitis B (...

THE deaths in Bhopal in December 1984 due to leakage of a highly toxic gas from a Union Carbide chemical plant are estimated at 2500 persons. The injured, in the tens of thousands, are still uncounted in what is well described as the worst industrial ...

Presentation of Case

A 70-year-old man was admitted to the hospital because of chronic diarrhea and weight loss.

He was in a stable state of health until three months earlier, when abdominal discomfort and bloating developed, followed by the passage of ...

On rare occasions a journal can publish two research papers back-to-back, each appearing quite sound in itself, that come to conclusions that are incompatible in whole or in part. Such a conjunction can put critical issues involving research methods and ...

In 1959 Ebashi et al. reported that plasma creatine kinase activity was elevated in patients with skeletal-muscle injury,¹ and in 1960 Dreyfus et al. reported similar findings in patients with acute myocardial infarction.² The increased diagnostic ...

DEATHS

Alexander — Leo Alexander, M.D., of Newton, died on July 20 at the age of 79.

Dr. Alexander graduated from Medizinische Fakultat der Universitat Wien in 1929. He was a member of the American Medical Association, the American Physicians Fellowship, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Usually a benign, self-limited disease, cat scratch disease is characterized by the appearance of an erythematous non-pruritic papule of the skin at the site of a cat's scratch. One to two weeks later, inflammation of regional lymph nodes ...

To the Editor: Detectable amounts of products of the platelet cyclooxygenase pathway, such as thromboxane A₂ and malondialdehyde, have been found in vivo, suggesting that platelets are activated in the circulation.^{1 , 2} The mechanisms by which platelets ...

No extract is available for articles shorter than 400 words.

To the Editor: Toxoplasmosis is one of the most diffuse parasitoses in the world. The responsible parasite Toxoplasma gondii is found in cattle as well as in sheep and pigs.^{1 , 2} The changes in food preparation and eating habits that have taken place ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

It is now 17 years since the second edition of Fractures of the Facial Skeleton (Rowe and Killey) appeared. Professor Killey has since died. Rowe and Williams have gathered a new group of contributors to produce this well-organized and very complete work ...

Barnes has edited and coauthored many chapters of this book, and his contributors include colleagues and faculty at the University of Pittsburgh. Pindborg, of Copenhagen, joins with contributors from eight additional American medical centers.

The scope of ...

The authors attempt to provide surgical knowledge that is "detailed and conceptually uniform." Their approach was to be "practical and inclusive." The attractive two-volume result of these efforts contains a wealth of information for both the resident and ...

This well-organized, straightforward, informative, and accurate book on the pancreas is extremely well done and, in terms of the integration of the various assigned units and chapters in the book, has avoided many of the problems of multiple authorship.

...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Enzyme Regulation. Vol. 23. Edited by George Weber. 463 pp., illustrated. Elmsford, N.Y., Pergamon Press, 1985. $160.

Advances In Hemostasis and Thrombosis. (Ettore Majorana International Science Series: Life Sciences. Vol. ...

MEDICAL LITERATURE ON LINE

A workshop on the National Library of Medicine's MEDLINE (Medical Literature on Line) system will be held at the MEDLINK Training Facility in Waltham, Mass., on November 6. The workshop will cover the basic operating commands, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Torture remains one of the most abhorrent concomitants of political repression today. In the past four years alone, governments in one third of the world's countries have systematically practiced or tacitly condoned torture or ill treatment.¹ Security ...