Graft versus host disease (GVHD) remains one of the primary causes of morbidity and mortality after allogeneic bone marrow transplantation. The antigens of the major histocompatibility complex were found early in transplantation to be important in both ...

Infertility is common among men. Approximately 14 per cent of couples in the United States are infertile,¹ and in 30 per cent of these the man is thought to have the primary abnormality.² Most male infertility for which a cause can be identified results ...

Since the first reports^{1 , 2} on the possibility of reducing the size of macroprolactinomas by dopamine agonists, the antitumor effect of these drugs has been largely confirmed by several studies showing that bromocriptine is effective in lowering ...

Approximately 25,000 people are admitted to British hospitals each year with acute upper gastrointestinal hemorrhage. About 20 per cent of them require emergency surgery, usually as a result of severe or persistent bleeding, and about 10 per cent die.^{1 , ...}

With the increasing use of cocaine in the United States, there has been a growing interest in the potential medical complications of cocaine use, including its effects on pregnancy, the fetus, and the neonate. In conjunction with the increased use of ...

Congressional attention has become increasingly focused on the rapid escalation in expenditures for physicians' services. Recent cost-control initiatives, like the Medicare fee freeze, are at best stopgap measures, because they do not address the growing ...

Advances in perinatal care have substantially reduced the number of serious complications associated with high blood pressure during gestation. Nevertheless, the hypertensive disorders of pregnancy remain a major cause of maternal and fetal morbidity and ...

Presentation of Case

First admission. A 69-year-old man was admitted to the hospital because of gastrointestinal bleeding.

There was a history of hypertension for 15 years, treated with hydrochlorothiazide and triamterene; diabetes mellitus was managed ...

The July 18, 1985, issue of the Journal contains five interesting articles^{1 2 3 4 5} dealing with the plight of teaching hospitals and with the implications of their sale to proprietary or for-profit entities. Reflecting the rapid changes taking place in ...

Traditional medical wisdom holds that patients who relate their complaints to their physicians from prepared lists are, ipso facto, emotionally ill. List writing, therefore, is called la maladie du petit papier, the illness of the little piece of paper, ...

DEATHS

Ciampa — Frank Ciampa, M.D., of Arlington, died on April 8 at the age of 74.

Dr. Ciampa graduated from Facolta di Medicina e Chirurgia dell'Universita di Napoli in 1936. He was a member of the American Medical Association, the American College of ...

No extract is available for articles shorter than 400 words.

To the Editor: Maternal serum alpha-fetoprotein screening at 16 to 18 weeks of gestation is being offered to a steadily increasing proportion of pregnant women in the United States. Elevated maternal serum alpha-fetoprotein levels lead to the detection ...

To the Editor: Pentamidine isethionate is used in the treatment of Pneumocystis carinii pneumonia, an opportunistic infection seen in about 60 per cent of patients with the acquired immunodeficiency syndrome (AIDS). Although renal toxicity due to ...

To the Editor: Evidence implicating immunologic mechanisms in the pathogenesis of Type I diabetes mellitus^{1 , 2} has led to clinical trials of immunosuppressive therapy.^{3 , 4} Recently, cyclosporine has been reported⁵ to decrease insulin requirements when ...

To the Editor: In their article on microvascular disease of the foot in diabetes (Dec. 20, 1984, issue),¹ LoGerfo and Coffman state, "There is a widespread misconception that patients with diabetes mellitus have arteriolar occlusive disease, which can ...

To the Editor: We have observed that the oral absorption of phenytoin may not be as consistent as previously described.^{1 , 2} The drug measurement service at St. Paul's Hospital in Vancouver, British Columbia, is responsible for the interpretation of all ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The "biomedical model," which serves as the foundation of contemporary, Western, scientific medicine, has at its core biologic theory, which seeks to explain the causes, pathophysiology, and course of illness.¹ It is the logic of this theory that dictates ...

In this short, unsentimental, posthumously published memoir by an experienced medical professor, the author looks at academic medicine objectively, facing defects and virtues with equal candor.

The treatment is rather diffuse and, at times, imprecise. ...

Though not many physicians are mountain climbers, the rush of interest in outdoor recreation and exploration has stimulated research in altitude physiology and prompted dozens of expeditions to high mountains. The most recent and ambitious of these was ...

Two decades is a long lapse for revision of a major treatise of physiologic concepts. Now, this first volume in a planned four-part Respiration Section of the Handbook of Physiology updates our thinking about pulmonary physiology. Other textbooks and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

At the outset of the first of these two books, the authors state that they are writing an unconventional textbook. It contains job descriptions for the new breed of paramedical persons and the roles in the team approach of rheumatologists, nurses, ...

To my knowledge, this is the first book on this subject. A scholarly discussion of the treatment of inflammatory diseases would be most welcome. One would hope that such a treatise would be based on reviews of carefully controlled clinical trials, perhaps ...

The 10 years that have passed since the publication of the first edition of this remarkable book have witnessed a growing interest in physical fitness. Joggers, marathon runners, jazz exercisers, and muscle builders abound; so, now, do coaches, trainers, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

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PSYCHIATRY AND THE LAW

The 16th annual meeting of the American Academy of ...