MARROW transplantation has been used with increasing success for the treatment of patients with various hematologic neoplasms, aplastic anemia, and immunodeficiency syndromes.^{1 2 3 4} However, the morbidity and mortality associated with marrow ...

HEREDITARY angioedema results from a genetic deficiency of the inhibitor of the first component of complement (C1). The C1-inhibitor deficiency allows unopposed activation of the complement system, and during this activation a peptide (or peptides) that ...

EPIDEMIOLOGIC studies have shown that ionizing radiation can induce leukemia and other cancers in adults and children.¹ Although several large studies have demonstrated an excess risk of childhood cancer of 40 to 50 per cent after prenatal irradiation of ...

ALTERATIONS of thyroid hormone economy occur in a variety of nonthyroidal illnesses. In these conditions, results of thyroid-function tests that would otherwise indicate thyroid dysfunction do not necessarily indicate hypothyroidism or hyperthyroidism. ...

THE cost of the Medicare End-Stage Renal Disease Program continues to increase, with current expenditures estimated to be $1.8 billion. Although the annual cost per patient has decreased (when adjusted for inflation),^{1 2 3} rising program costs have led to ...

THE objectives of treatment of the pregnant woman with epilepsy are to maintain the patient in a seizure-free state while minimizing when possible the adverse effects of the seizure disorder on the course of the pregnancy and the possible teratogenetic ...

MANY cases of familial cancer have been reported, but relatively few inherited cancers have been shown to be associated with specific known genes or specific chromosome regions. Meningioma is an uncommon, usually sporadic, central nervous system tumor. In ...

Presentation of Case

A 43-ycar-old woman was admitted to the hospital because of hypertension and hematemesis.

She was well until six months earlier, when she began to experience headaches that were accompanied by nausea and vomiting. Intermittent bouts ...

Nearly 30 years after Stewart and colleagues presented data showing an increased risk of cancer for children who were exposed to diagnostic x-rays while in utero,¹ the meaning of this association remains unclear. Although the observation has not been ...

Twenty-five years ago, almost to the exact date of this publication, the first patient with irreversible chronic renal failure was started on repetitive treatments with an artificial kidney with the goal of extending meaningful life for months or years.¹ ...

This paper is intended to respond, on the basis of current trends, to the question, What does the future hold for the organization of health care delivery in the next 20 years? The reader is left to decide whether the projections of current events in this ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The increase in alcoholic liver disease among women has caused much speculation about whether they may be more susceptible than men to the hepatotoxic effects of alcohol. Women are at a greater risk for the development of cirrhosis if ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Primary peritonitis (spontaneous bacterial peritonitis) is very rare after the age of 10 years and has occasionally been described in adults who have cirrhosis or the nephrotic syndrome or who have undergone splenectomy. Late infections in ...

To the Editor: Cushing's disease (pituitary-dependent adrenal hyperplasia) continues to challenge the most discerning clinicians. Delineating the cause and treating the source of the hypercortisolism are often difficult, particularly in patients who have ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Health maintenance organizations (HMOs)^{1 2 3 4 5 6 7} were first developed on a large scale around the turn of the 19th century, but were not then known as HMOs. These earliest forms were called prepaid group practices, and most of them originated in the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This book makes a major contribution to the literature on the kidney and electrolyte metabolism. It fills a special void that is created by the dogmatic and simplistic approach of much medical education. Uncertainty seems to generate tremendous anxiety in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Biotechnological Processes. Vol. 3. Edited by Avshalom Mizrahi and Antonius L. van Wezel. 361 pp., illustrated. New York, Alan R. Liss, 1984. $68.

Autonomic Functions in Human Physiology. By Gerhard Thews and Peter Vaupel. ...

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HEALTH POLICY

A conference entitled "Cost vs. Care: America's Health Care ...