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January 17, 1985  Vol. 312 No. 3

Original Articles
137-141

IN 1974 a report by Cameron and Campbell raised the possibility that high-dose vitamin C might be of value in the treatment of advanced cancer.1 It stated that among 50 patients who were treated with vitamin C at a daily dose of 10 g, 5 had objective ...

142-146

    ALTHOUGH taurine (2-aminoethane sulfonic acid) has been considered a nonessential amino acid for human beings,1 , 2 several studies have raised the question whether preterm and full-term neonates have a dietary need for it.3 4 5 6 7 8 9 Cats, beagle pups, ...

    146-151

    WOMEN who have undergone a breast biopsy for benign disease have an increased risk of breast cancer.1 , 2 These biopsies reflect a spectrum of histologic conditions, from normal breast tissue of varying physiologic states at one extreme, to changes ...

    152-158

      SUBCLASSIFICATION of patients with lung fibrosis is both difficult and controversial. Even though investigators have used different criteria and different names, most have recognized one subgroup with an almost uniformly poor prognosis. Patients with this ...

      Mechanisms of Disease
      159-163

      ISCHEMIA-induced pathologic processes are responsible for the single greatest cause of death in this country — heart disease; cerebral ischemia also makes a major contribution to our nation's morbidity and mortality. A relatively subtle indicator of ...

      Medical Intelligence
      164-165

      THE current trend in ethical discourse is not merely to analyze the differences between good and evil but to examine ethical dilemmas — i.e., situations in which there is some good and perhaps some harm on both sides.1 , 2 The dilemma presents a problem ...

      165-167

      ALUMINUM can accumulate in patients with reduced renal function due to impaired excretion of aluminum1 , 2 and in patients with normal renal function who receive large parenteral amounts of aluminum.3 Manifestations of aluminum toxicity include vitamin D–...

      167-170

      VERAPAMIL is a calcium-channel blocking agent that has been used extensively in the treatment of coronary vasospasm1 and supraventricular arrhythmias.2 , 3 Its negative inotropic and chronotropic actions as well as its vasodilator effect make it useful in ...

      Case Records of the Massachusetts General Hospital
      171-177

      Presentation of Case

      A 33-year-old man was admitted to the hospital because of facial weakness and ophthalmopleia without ptosis.

      He was well until 15 years earlier, when it was observed that he was unable to close his right eyelids fully when asleep. Two ...

      Editorials
      178-179

      This issue of the Journal contains the most recent chapter in a very interesting and probably unfinished story: Does ascorbic acid have a role in the treatment of human cancer? By the late 1960s several lines of evidence led to the notion that this ...

      179-181

      IT is time to empty the "fibrocystic disease" waste-basket and thereby mitigate the anxiety of a large number of women who no longer need to be concerned about a high risk for breast cancer. Love et al. have asked, "Is it reasonable to define as a disease ...

      Sounding Board
      181-183

      Two thirds of the American public now believe that people are beginning to lose faith in doctors.1 The growth of public disillusionment with physicians as a professional group has accompanied magnificent medical advances. In some sense, Aaron Wildavsky's ...

      Correspondence
      183-185

      No extract is available for articles shorter than 400 words.

      185

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      185

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      186

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      186

      No extract is available for articles shorter than 400 words.

      186

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      186-188

      No extract is available for articles shorter than 400 words.

      188

      No extract is available for articles shorter than 400 words.

      188-189

      No extract is available for articles shorter than 400 words.

      189

      No extract is available for articles shorter than 400 words.

      Book Reviews
      189-190

      Substance abuse is one of today's major health concerns. The seriousness of the drug epidemic is most apparent among adolescents and young adults. Drug use is a major contributor to many physical, psychological, and social problems of our youth. Accidents,...

      190

      The first of these two books occasionally suffers from the expected disparities in style and depth of a multiauthored work, and yet for the most part these shortcomings have been minimized by careful organization. The book provides concise reviews ...

      190-191

      This slim volume deals with some major issues in the menial and physical health of female adolescents. The contributors were asked to provide up-lo-date information about commonly encountered health problems of adolescents, together with current treatment ...

      191

      Because of its multidisciplinary approach, the first of these two books is specifically appropriate for those who provide services to suicidal persons, as well as the bereaved survivors. Unfortunately, most of the chapters are redundant and anecdotal, and ...

      191-192

      Suicide is the third leading cause of death among adolescents, and rates of suicide among young people are increasing sharply. This book provides an essential summary of what is known about the phenomenon of suicide among young people, and discusses ...

      Notices
      192

      Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

      NEPHROLOGY

      The Fourth International Symposium of Nephrology, entitled "Newer ...

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