THE newborn with myelodysplasia (meningomyelocele or a related disorder) presents a technical and ethical challenge. Continuing judiciary and legislative activity illustrates the breadth of this challenge in our society.^{1 2 3} Arguments for and against the ...

THE membrane attack complex of complement, activated by either the classical or the alternative pathway,¹ destroys cells by creating transmembrane channels.^{2 , 3} Recent immunohistochemical studies have demonstrated that the attack complex is deposited in ...

CURRENT therapy of patients with beta-thalassemia includes the regular use of deferoxamine for iron chelation. Such chelation therapy in patients given transfusions can produce a negative iron balance¹ and can lower the levels of serum ferritin,^{1 , 2} ...

ALTHOUGH cancers are usually "staged" according to morphologic evidence of the tumor's anatomical dissemination and histologic type, the prognosis can also be affected by nonmorphologic features of the patients' clinical condition. Among these clinical ...

MYOPIA is a very common refractive error (25 per cent prevalence in the United States¹), in which the image of distant objects falls in front of the retina; in most cases, it is a developmental anomaly characterized by excessive elongation of the eye.² ...

WHETHER diagnosed as Crohn's disease or ulcerative colitis, chronic nonspecific inflammatory bowel disease is particularly likely to afflict young adults. It is therefore not at all unusual to encounter women with inflammatory bowel disease who are ...

VISCERAL larva migrans is a subacute inflammatory disease characterized by hepatomegaly, eosinophilia, and hypergammaglobulinemia and due to the larval migration in human beings of nematodes normally parasitic in lower animals.^{1 , 2} Most cases in the ...

Presentation of Case

A 27-year-old man was admitted to the hospital because of hematuria.

He was well until 13 years earlier, when total, gross, painless hematuria developed several hours after trauma to the left flank in a bicycle accident. He was seen ...

This year has seen a notable attentiveness toward the problem of the newborn with birth defects, specifically myelomeningocele. In the legal sphere, the new child-abuse act legislates against "withholding of medically indicated treatment" unless (1) the ...

The National Institutes of Health (NIH) has earned a reputation for excellence in the support and conduct of research to improve the health of the American people. It has maintained its leadership position in the international scientific community in the ...

Baker — Harry Abraham Baker, M.D., of Holyoke, died on April 24 at the age of 77.

Dr. Baker received his degree from Tufts College Medical School in 1932. He was a member of the American Medical Association and the American College of Cardiology. Dr. ...

No extract is available for articles shorter than 400 words.

To the Editor: Spontaneous healing has been described in classic Kaposi's sarcoma and may represent up to 10 per cent of these forms.¹ It has also been observed in recipients of renal allografts, the sarcoma sometimes disappearing when immunosuppression ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recently, proponents of "alternative" cancer therapy programs both in the United States and abroad have become increasingly effective in interesting a substantial portion of the population in their theories and products. It has therefore ...

No extract is available for articles shorter than 400 words.

To the Editor: In 1983 Matsui et al.* reported on the natural history of methylmalonic acidemias. They demonstrated the poor prognosis for this condition in cases of partial or total lack of methylmalonyl-CoA mutase apoenzyme.

We diagnosed one such case ...

To the Editor: Prostacyclin has been shown to dilate cerebral vessels, inhibit platelet thromboxane A₂ production, enhance fibrinolysis, and protect cells against damage. These properties suggest that prostacyclin should be evaluated as a treatment for ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I believe there are some misleading or incomplete statements in the article by Bockman, Kingsbury, McKinley, Bendheim, and Prusiner on Creutzfeldt–Jakob disease (Jan. 10 issue).¹

First, there is no evidence for cross-reactivity or ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Test-ordering strategies are receiving much attention, as physicians, hospitals, and laboratories adjust to the environment created by diagnosis-related groups. More judicious use of test profiles and multichannel analyzers has been ...

The publication of this comprehensive textbook reflects the development of geriatrics as a field of academic study and clinical practice. This society is facing an increasingly aged population and demonstrating ambivalence about supporting their economic ...

There is no doubt that this is one of the current major books in geriatrics. Many of the chapters are excellent. The editors are all investigators who have made major contributions to our understanding of biologic aging, and their chapters reflect this in ...

The health needs of the elderly are many, pressing, and complex. As our nation's aged population continues to grow, it is increasingly apparent that the practice of geriatrics must have more than a narrow medical focus. In addition to the physical ...

This book presents contributions on various aspects of the theory and treatment of addictions.

It is divided into two parts; the first half covers theoretical perspectives on the pathogenesis of addictions, and the second half different approaches to the ...

No extract is available for articles shorter than 400 words.

This unusual book should appeal to several audiences. Nonmedical persons may learn about the anatomy and function of the human body and understand the excitement that motivates physicians. Experienced practitioners may recall the thrill and appreciation ...

No extract is available for articles shorter than 400 words.

Health Policy

Community Services for the Mentally Retarded. By Arnold Birenbaum and Herbert J. Cohen. 193 pp. Totowa, N.J., Rowman and Allanheld, 1985. $28.95.

Feeling Good and Doing Better: Ethics and nontherapeutic drug use. Edited by Thomas H. Murray, ...

PSORIASIS

The Department of Dermatology at Stanford University Medical Center in California will sponsor the Fourth International Symposium on Psoriasis at the University, July 7–12.

Contact Dr. Paul H. Jacobs, Department of Dermatology, Stanford ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.