Multiple sclerosis is a chronic demyelinating disease of the central nervous system.^{1 2 3} On pathological examination, there is demyelination of white matter associated with a mononuclear-cell infiltrate that consists predominantly of T cells and ...

Renin is an enzyme that cleaves plasma angiotensinogen to release angiotensin I, which in turn is cleaved to yield angiotensin II, a potent vasoconstrictor and stimulus for adrenal production of aldosterone. Plasma also contains a zymogen, inactive renin, ...

Parkinsonism results from the exposure of human beings to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) either as an impurity of an illicit narcotic^{1 , 2} or accidently during synthesis of the chemical.³ Its chemical structure is shown in Figure 1. ...

Knowledge of enteric bleeding patterns in health and in gastrointestinal diseases has been limited by the lack of a simple means to measure fecal blood. Assays based largely on the fecal recovery of intravenously injected Radio-labeled red cells¹ are ...

Permanent cardiac pacing, particularly by the relatively simple and safe transvenous method, must rank as one of the great cardiologic advances of the 20th century, with a record of thousands of lives saved and more thousands of patients relieved of ...

Peripartum cardiomyopathy is a relatively uncommon form of heart failure affecting women in their reproductive years. It is usually defined as cardiomyopathy first presenting in the last month of pregnancy or the first six months post partum.¹ Additional ...

Torsion dystonia (dystonia musculorum deformans) is a movement disorder that may be genetic, environmental, or idiopathic in origin.¹ The hereditary forms usually begin in childhood or adolescence with involuntary posturing of the foot or hand in the ...

Presentation or Case

An 88-year-old man was admitted to the hospital because of a right pleural effusion.

He was in a stable state of health until two weeks before admission, when pruritus developed in the left side of the chest, followed by a vesicular ...

Physicians are faced all too frequently with middle-aged patients who present with vague abdominal problems or rectal bleeding and who on evaluation are found to have colon cancer. A discouraging proportion of these relatively young people already have ...

Congress approved the funding of 6500 new research grants in 1985, but the Office of Management and Budget proposed to stretch the process out and keep the number of new grants this year at its present level. A compromise figure is now being discussed, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Human α-atrial natriuretic polypeptide (α-hANP) is a potent vasoactive and natriuretic peptide that was recently identified in human atrial extract.¹ Although α-hANP is involved in fluid and electrolyte balance in dogs and rats,^{2 , 3} its ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is a compact volume that combines the best features of a self-instructing review of orthopedic diagnosis with a concise reference work to summarize the diagnosis and treatment of skeletal diseases. The three authors present clinical, radiological, ...

No extract is available for articles shorter than 400 words.

This is the second of a proposed four-volume set dealing primarily with basic surgical techniques in hand surgery and specific hand injuries. The work is encyclopedic in nature, with 119 chapters by 101 contributors.

The first two sections outline basic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Readers wishing to know the current status of cataract surgery will find most of their questions answered in either of these two books. Both emphasize that the current trend is toward extracapsular cataract extraction with implantation of posterior-...

Radiology

Diagnostic Interventions In Nuclear Medicine. Edited by James H. Thrall and Dennis P. Swanson. 276 pp., illustrated. Chicago, Year Book, 1985. $39.95.

Emergency Orthopaedic Radiology. By Robert J. Neviaser, Larry S Elsenfeld, Sam W. Wiesel, and ...

EMERGENCY CARE

Harvard Medical School will sponsor a course for emergency medicine physicians — "Emergency Care: An Extended Workshop" — at Massachusetts General Hospital, September 23–October 4. The fee is $950.

Contact Barbara Wagner, Medical Education ...