Over 100 years ago, quinidine, a cinchona alkaloid, was found to be effective against Plasmodium falciparum malaria in India.¹ Later investigations in Malaya,² Louisiana,³ and New York⁴ produced evidence that quinidine was as effective as quinine as an ...

The intestinal protozoan cryptosporidium is a well-known cause of gastroenteritis in animals and has recently been shown to cause a similar illness in human beings.^{1 2 3 4} The organism was initially described on the gastric mucosa of asymptomatic mice in ...

Microangiopathy can markedly reduce the life expectancy of the patient with diabetes, owing to the development of advanced nephropathy and renal failure, and can cause serious morbidity, especially blindness. Furthermore, diabetic angiopathy has continued ...

The HLA chromosomal region, or major histocompatibility complex — located on the short arm of chromosome 6 — is a cluster of at least three gene families coding for cell-surface proteins (class I and class II molecules) and several complement factors (...

THE acquired immunodeficiency syndrome (AIDS) was first reported in 1981 in homosexual men and intravenous drug abusers.^{1 2 3 4 5} Subsequent cases in persons with hemophilia^{6 7 8 9} and recipients of blood transfusions^{10 , 11} confirmed a pattern of ...

The Epstein–Barr virus is a ubiquitous B-cell lymphocytotropic virus that is known to cause infectious mononucleosis¹ and lymphoproliferative disorders in immunodeficient patients² and has been implicated in the genesis of Burkitt's lymphoma³ and primary ...

Lipoprotein particles transport cholesterol and triglycerides in the bloodstream. Abnormalities of plasma lipoproteins can result in a predisposition to premature coronary artery disease, pancreatitis, or neurologic disease. Recent advances in our ...

Presentation of Case

A 39-year-old man was admitted to the hospital because of melena and abdominal pain.

He was well until one month earlier, when he began to experience intermittent bouts of pain in the right lower abdominal quadrant; the pain was ...

Acute diarrhea is rivaled in importance only by respiratory infection as a cause of morbidity on a worldwide scale. A key to preventing or controlling enteric infection is identifying the responsible agents. With the discoveries of enterotoxigenic ...

The key role of the thymus gland in the establishment and maintenance of cell-mediated immune responses has been known since the pioneering work of Martinez et al.¹ and Miller² in the early 1960s. This function is carried out through a close interaction ...

In recent years a number of attacks have been made on the cost of graduate medical education.^{1 2 3} The argument is that the house staff should not be paid from patient revenues, although how it is supposed to be paid is by no means clear. In my view, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Chess and Thomas report findings from their New York Longitudinal Study, which followed 133 subjects from early infancy to young adulthood. General readers will find much of interest, but two key chapters require advanced statistical training. The authors'...

Brain and Psyche makes important findings in experimental neuroscience accessible to psychiatrists and explains core psychoanalytic concepts to neuroscientists. The author, a neuroscientist at Rockefeller University, places technical details in ...

No extract is available for articles shorter than 400 words.

Miës van de Rohe's dictum that "Less is more" seems an apt description of the fourth edition of this popular textbook, now in its adolescence (the first edition was published in 1967). Since the publication of the third edition in 1980, the number of ...

Since the epidemic of hallucinogenic drug abuse swept the United States 20 years ago, scientists have persisted in examining the psychobiology of these powerful agents. This book is a compilation of that work, a review of nearly 1000 original papers in ...

This book addresses the "what," "who," and "how" of nightmares. The author, a psychoanalyst and sleep researcher, is eminently qualified to write a book on this subject. One of the strongest features of this book is its cogent examination of post-...

Health Policy

Canadian Medicine: A study in restricted entry. By Ronald Hamowy. 394 pp. Vancouver, B.C., Fraser Institute, 1984. $14.95.

The Coming Physician Surplus: In search of a policy. Edited by Eli Ginzberg and Miriam Ostow. 131 pp. Totowa, N.J., ...

PEDIATRIC ENTERIC INFECTIONS

The Thrasher International Conference on Pediatric Enteric Infections will be held in Salt Lake City, June 13–15.

Contact Dr. John M. Matsen, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.