PRECOCIOUS sexual development has been divided classically into two broad pathophysiologic categories.¹ True or central precocious puberty refers to the premature but otherwise normal hypothalamic mediation of gonadarche, with maturation of both sex-...

IN 1920 Creutzfeldt described a progressive dementing illness in a 22-year-old woman.¹ The following year, Jakob described four older patients with a clinically similar presentation and course.² During the ensuing four decades, numerous cases of ...

INFUSION-related phlebitis is a painful and potentially fatal iatrogenic disorder.¹ The literature suggests a limited comprehension of both the potentially varied causes and the actual clinical spectrum of this syndrome, partly because of the failure of ...

IN the past two decades, the infant mortality rate (deaths under one year of age per thousand live births) in the United States has declined sharply. Now well established, this trend has elicited great interest, in part because it follows a period of ...

THE incidence of cutaneous malignant melanoma is rising rapidly throughout the world.¹ The most current data from the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) system reveal an 80 per cent increase in the incidence of ...

A RECENT report by Scott et al. described antibodies to a soluble tissue ribonucleoprotein antigen called Ro(SS-A) in the serum of 34 of 41 mothers who had given birth to infants with congenital complete heart block.¹ Less than half the mothers had ...

PREVIOUS reports have established the utility of selective catheterization of the inferior petrosal sinus for determination of plasma ACTH concentrations in the diagnosis of pituitary-dependent hypercortisolism.^{1 2 3 4 5} Preliminary studies suggest that ...

Presentation of Case

A 57-year-old woman was admitted to the hospital because of fever of unknown origin.

She was well until four months earlier, in late summer, when she began to feel unwell. A physician obtained an intravenous urographic examination, ...

Intravenous devices are inserted in approximately half the 40 million patients hospitalized each year in the United States.¹ The great benefits of administration of fluids and medication by this direct route to the circulation are obvious. The hazards are ...

"Fear has big eyes." This proverb describes our feelings about cancer: we are all afraid of cancer and we are continually seeking clues to detect it as early as possible. Unfortunately, there are few early warnings. Although self-examination of the ...

In our editorial in the Journal in 1978,¹ Kaplan and I discussed the observations of Koster et al.² on shigella-associated hemolytic uremic syndrome, which suggested that endotoxin damaged vascular endothelium and set in motion events leading to the full-...

No extract is available for articles shorter than 400 words.

To the Editor: During the past three years I have developed projections for cardiac-surgery volumes in the United States. In connection with this effort, I have reviewed national trends in coronary-artery bypass volumes. I was surprised to learn that ...

No extract is available for articles shorter than 400 words.

To the Editor: Farr et al. (June 28 issue)¹ have presented an interesting case of acute gastric volvulus and electrocardiographic changes simulating acute inferior-wall myocardial infarction. They postulate that either cardiac rotation or pericardial ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The clinicopathological exercise in the September 20 issue, entitled "Hypertension and an Adrenal Mass after a Vehicular Accident,"¹ neglects essential elements of the case. By using the word "accident," the authors imply that the patient'...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This is one in a series of monographs on special areas of surgery. It provides an updated view rather than comprehensive coverage of the field of vascular surgery. As indicated in the preface, the editors have addressed many of the main areas of interest, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This book is recommended for orthopedic residents and practicing orthopedic surgeons with a special interest in motorskeletal-system anatomy. Bibliophiles with a reverence for eponyms in the history of surgery will find what they want in the lists of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Hundreds of medical books are published each year, but only a few become standard references in clinical practice, research, or education. These are books that are so well known that they can be referred to unambiguously simply by the name of the author. ...

Radiology

Ultrasonic Differential Diagnosis of Tumors. Edited by George Kossoff and Morimichi Fukuda. 303 pp., illustrated. New York, Igaku-Shoin, 1984. $59.

Ultrasound in Breast and Endocrine Disease. (Clinics in Diagnostic Ultrasound. Vol. 12.) Edited ...

EUTHANASIA

The Second National Voluntary Euthanasia Conference will be held at the Miramar Sheraton Hotel in Santa Monica, Calif., February 8 and 9. The fee is $130.

Contact Susan Waller, Hemlock Society, P.O. Box 66218, Los Angeles, CA 90066; or call (...

After more than a decade of congressional debate and five years of program experimentation, the federal government is on the threshold of launching a major effort to enroll Medicare beneficiaries in health maintenance organizations (HMOs) and other ...