RECENT studies indicate a close association between newly discovered human retroviruses and the acquired immunodeficiency syndrome (AIDS).^{1 2 3 4 5 6 7 8 9} The vast majority of patients with AIDS have antibodies to human T-cell lymphotropic virus III (...

SHORT stature may be secondary to growth hormone deficiency, which may be idiopathic or may result from dysfunction of or structural damage to the hypothalamus or hypothalamo-hypophyseal stalk. Such dysfunction or damage leads to lack of normal ...

THE clinical features of acromegaly result directly or indirectly from sustained hypersecretion of growth hormone.^{1 2 3} Somatotroph-cell adenomas, or in rare cases hyperplasia, constitute the pathologic pituitary lesions causing acromegaly.^{4 , 5} Also in ...

PANCREATIC cholera is characterized by watery diarrhea, hypokalemia, and acidosis¹ and in most cases is due to a non-β-islet-cell tumor of the pancreas that secretes vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine.² When such ...

MULTIFOCAL atrial tachycardia is a distinct electrocardiographic entity characterized by an atrial rate of more than 100 beats per minute, the presence of at least three different P-wave forms, and variation in the PR and PP intervals.¹ The condition ...

IT has long been known that some cellular proteins bind guanine nucleotides such as guanosine tri-phosphate (GTP) with high affinity. These binding proteins are called G proteins and have been linked to such critical intracellular functions as protein ...

Presentation of Case

First admission. A 21-year-old woman was admitted to the hospital because of hemoptysis and cavitary pulmonary lesions.

She was well until 21 months earlier, when she began to have pleuritic anterior chest pain that radiated to the ...

A half century ago the two standard textbooks on cardiovascular disease allotted little space to the subject of paroxysmal auricular tachycardia.^{1 , 2} Concepts about this dysrhythmia were few, and advice about therapy was brief. Concentrating on ...

IN his classic book Principles of Psychology, published in 1890, the great psychologist-philosopher William James stated that "chemical action must of course accompany mental activity, but little is known of its exact nature." ¹ The year 1984 marks the ...

IN 1978 Parkman et al.¹ reported the complete correction of the Wiskott–Aldrich syndrome in two patients by allogeneic marrow transplantation after preparation with antihuman thymocyte serum and total-body irradiation. The article and the accompanying ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

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To the Editor: We were very interested in the article by Peltola and colleagues reporting the effectiveness of immunization with a capsular polysaccharide Hemophilus influenzae type b (Hib) vaccine in preventing H. influenzae bacteremic infections in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The possible transmission of the acquired immunodeficiency syndrome (AIDS) to health care workers has been of great concern since the epidemic was recognized over three years ago. That needlestick exposure is sufficient to transmit ...

No extract is available for articles shorter than 400 words.

Prematurity is the leading cause of perinatal morbidity and mortality for newborns without congenital anomalies. The importance of preterm delivery has become magnified in recent years as developments in maternal–fetal medicine and neonatology have ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Cyclic Nucleotide and Protein Phosphorylation Research. Vol. 18. Edited by Paul Greengard and G. Alan Robison. 287 pp. New York, Raven Press, 1984. $49.50.

Advances in the Biology of Disease. Vol. 1. By Emanuel Rubin and ...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL, BOSTON

The Hospital will offer two seminars in January in the Grossman Conference Center of Kirstein Hall on Tuesdays at 4:30 p.m.: "Physiologic and Clinical Implications of Muscarinic Receptor Subtypes" ...

IN June 1984, physicians in New South Wales (NSW), Australia, voted overwhelmingly to resign from public hospitals, and by July 2, 1559 resignations had been received by hospital administrators. These resignations were in defiance of government ...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...