WE conducted a study to determine whether exposure to diethylstilbestrol (DES) during pregnancy increases a woman's risk of breast cancer. DES is associated with vaginal and cervical adenocarcinomas in females exposed in utero.^{1 2 3} In addition, two ...

EARLY-PHASE and late-phase (dual) reactions have been observed in asthmatic subjects after either an allergen-inhalation challenge^{1 2 3 4} or exercise provocation tests.^{5 6 7} In both situations mast-cell–associated high-molecular-weight neutrophil ...

OBESE subjects characteristically have blunted responses to all stimuli of growth hormone release and, after successful weight reduction, they have partial or complete restoration of normal growth hormone responsiveness.^{1 2 3 4 5 6 7} Since all the stimuli ...

IN 1905, von Pirquet and Schick provided the first detailed description of serum sickness in human beings.¹ Their patients were children who were being treated with horse serum containing diphtheria antitoxin. Eight to 12 days after subcutaneous ...

MICROBIAL invasion, tissue injury, immunologic reactions, and inflammatory processes induce a constellation of host responses collectively referred to as the acute-phase response. The response is characterized by changes in metabolic, endocrinologic, ...

THE epidemiology of the acquired immunodeficiency syndrome (AIDS) strongly suggests a transmissible agent, such as a virus, as its cause.^{1 2 3} Transient viral infections in normal hosts with agents such as cytomegalovirus, hepatitis B, and Epstein–Barr ...

AFTER the appearance of sporadic cases in 1961,¹ the incidence of methicillin-resistant Staphylococcus aureus infections in the United Kingdom,² Scandinavia,³ and Europe⁴ increased gradually throughout the 1960s, reaching a peak at the end of the decade ...

Presentation of Case

A 43-year-old right-handed man was admitted to the hospital because of headache and visual disturbances.

He was well until three days earlier, when he experienced the sudden onset of a "flashing" light in the left visual field, ...

IN this issue of the Journal, Greenberg et al.¹ report a collaborative study, involving approximately 6000 women, in which a small but significant increase in the risk of breast cancer was observed in those exposed to diethylstilbestrol (DES) during ...

The article by Lawley et al.¹ in this issue of the Journal provides an excellent description of the clinical and immunologic features of serum sickness in patients with bone-marrow failure who received antithymocyte globulin in horse serum. This group of ...

Six years ago, one of us (W.G.A.) commented in the Journal on the current status of cardiac transplantation.¹ The editorial concluded that the procedure, under certain special conditions, could be considered a rational and socially acceptable therapy for ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We have recently encountered a homosexual man with the chronic lymphadenopathy syndrome and a Sjögren's-like illness. Autoimmune phenomena have been described in homosexual men and attributed to nonspecific B-lymphocyte activation and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Dr. Fulkerson states that the purpose of his review of bronchoscopy is to help physicians understand fiberoptic bronchoscopy (Aug. 23 issue).¹ "Fiberoptic bronchoscopy" is not synonymous with the use of flexible instruments only. Rigid ...

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To the Editor: In "Policies on Exportation of Hazardous Substances in Western Developed Countries: A Public-Health Problem" (Aug. 23 issue), Navarro takes industry to task.* However, this is a political problem, not a public-health problem; although we ...

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These two books deal with two different aspects of the psychological consequences of trauma: the first focuses on the psychological rehabilitation of physical trauma, the second on the psychological trauma of war. The first book is well organized, ...

Intrahepatic calculi are commonly seen in the Far East but are uncommon in Western countries. A complete volume on this important subject (as stated by the editors, two from Japan and one from Hong Kong) should be beneficial not only to the medical ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

CRYOSURGERY

The Seventh Annual Meeting of the American College of Cryosurgery ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The National Institutes of Health (NIH), vested with more money and higher acclaim by Congress than ever before, enjoys a reputation that is perhaps without equal among federal agencies. Yet, even at the height of its standing in the political arena, this ...