LYMPHADENOPATHY-associated virus (LAV) is a newly identified exogenous human T-cell lymphotropic retrovirus, first isolated from nodal tissue of a homosexual man¹ and subsequently recovered from T cells of hemophiliacs and other patients with the acquired ...

OSTEOPOROSIS is associated with an estimated 700,000 fractures in postmenopausal women in the United States each year.¹ Both estrogen deficiency and aging have been implicated in its pathogenesis. A causal role for estrogen deficiency is supported by the ...

EXERCISE radionuclide ventriculography is increasingly considered a superior noninvasive screening test for coronary-artery disease. Its sensitivity and specificity have been shown to exceed those of non-imaging exercise studies.^{1 2 3 4} As with all ...

MORE than four decades have passed since the initial observations of Huggins and Hodges and their colleagues regarding the efficacy of castration or estrogen therapy in relieving the symptoms of metastatic prostate carcinoma.^{1 2 3} During this time, ...

THE acquired immunodeficiency syndrome (AIDS) is a novel, epidemic form of immunodeficiency that has been widely recognized within the past three years.^{1 2 3} Full-blown AIDS, as defined clinically by the Centers for Disease Control surveillance definition,...

APPROXIMATELY three years ago an apparently new and unexplained disorder called the acquired immunodeficiency syndrome (AIDS) was recognized. Prompt worldwide recognition of this syndrome was brought about by a truly remarkable collaboration between ...

THE early diagnosis of pheochromocytoma is important, not only because it offers the possibility of curing hypertension but also because unrecognized pheochromocytoma is a potentially lethal condition. Hypertensive crisis or shock or both leading to death ...

Presentation of Case

A 63-year-old man was admitted to the hospital because of dyspnea.

He was well until 26 months earlier, when weakness developed. He was referred to this hospital, where physical examination was negative. The hematocrit was 30.6 per ...

Three articles in this issue of the Journal discuss new information about the acquired immunodeficiency syndrome (AIDS). One reviews the immune abnormalities in the disease and their relation to immunodeficiencies in other human disorders and in animal ...

Most patients with a diagnosis of prostate cancer already have metastases or will have them despite treatment aimed at the primary tumor in the prostate gland. The axial skeleton is the predominant site of dissemination; bone pain is the usual source of ...

IN March 1983 Congress enacted a sweeping change in the payment mechanism for Medicare. The four-year transition (1984 to 1987) from retrospective, cost-based reimbursement to prospective pricing by diagnosis-related group (DRG) for most inpatient ...

To the Editor: The ear-lobe crease has been demonstrated to be significantly associated with coronary-artery disease in specific populations.¹ Patterns of hair growth have previously been suspected as possible risk factors for coronary-artery disease.^{2 ,} ...

To the Editor: The recent comment by Breitner and Folstein (July 19 issue)¹ that the "90-year lifetime incidence of dementia in siblings or children of Alzheimer's disease probands with aphasia or apraxia approached 50 per cent" was not based on ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The absence of benefits observed by Pepe et al. (Aug. 2 issue)¹ in the prevention of the adult respiratory-distress syndrome by early application of prophylactic positive end-expiratory pressure (PEEP) and the editorial in the same issue ...

To the Editor: We agree with the statement of Andreoli et al. (April 26 issue) that gastrointestinal absorption of aluminum can lead to aluminum intoxication.¹ However, there are shortcomings in the way they reach that conclusion. They combine the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As I have grown older I have learned that most of one's opportunities are both "good news" and "bad news." This was certainly true when I was asked by the Journal to do a comparative review of several major textbooks of internal medicine.

On the one hand, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This book was written as a guide for British general practitioners providing ongoing care to the elderly. The author has drawn heavily from his own experience.

The first section, on epidemiology and resources, provides a broad overview of topics, such as ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.