AMYOTROPHIC lateral sclerosis (ALS) is a fatal disease of unknown cause. Survival usually ranges from two to four years, but cases with a more rapid or a more protracted course are encountered, and 20 per cent of patients survive for more than five years.^...

LEUKEMIC cells can now be classified into different types and subtypes on the basis of their expression of distinct surface markers,¹ reactivities to a broad array of antibodies,^{2 3 4 5} and lymphoblast morphology.⁶ Analysis of the phenotypic profiles of ...

STUDIES of the prognosis for seizure control in epilepsy have given widely conflicting results (Table 1). In an authoritative review Rodin⁶ found that if control was defined as complete freedom from all seizures for at least one year, then about two ...

MULTIPLE sclerosis is a common, often severe neurologic disorder for which the cause, cure, and prevention are unknown and for which no specific diagnostic biologic test exists. In clinical studies addressing these issues it is critical to exclude ...

DIABETES is frequently associated with elevated concentrations of total plasma triglyceride and low-density-lipoprotein (LDL) cholesterol and reduced concentrations of high-density-lipoprotein (HDL) cholesterol.^{1 2 3 4 5} Both coronary and peripheral ...

THE system of mental-health care in the United States is undergoing a marked "privatization," and the rapid increase in the number of investor-owned psychiatric hospitals is causing concern.^{1 2 3} This focus on investor-owned psychiatric hospitals has, ...

INFECTIOUS mononucleosis is the best-known syndrome associated with primary infection by the Epstein–Barr virus (EBV). A variety of cutaneous and mucosal manifestations are recognized, but genital lesions have only rarely been described in infectious ...

Presentation of Case

A 65-year-old woman was admitted to the hospital because of pulmonary nodules.

There was a 28-year history of anterior chest pain relieved by nitroglycerin. Eighteen years before admission a right radical mastectomy was performed ...

Amyotrophic lateral sclerosis (ALS) is not a common disease, but it has become widely known. Many people know it by the name of one famous victim, the baseball player Lou Gehrig. Other affected celebrities have included former Vice-President Henry A. ...

IN the past few years there has been a dramatic rise in the demand for organs for transplantation. Advances in surgical techniques, tissue typing, and the development of powerful immunosuppressive drugs, such as cyclosporine, has made it possible to ...

I have just returned from providing an ethics consultation involving one of the situations clinicians hope never to face. A full-term male infant, otherwise healthy, was born with a gastroschisis. Laparotomy on the second day of life revealed no more than ...

No extract is available for articles shorter than 400 words.

To the Editor: Pyridoxine (vitamin B₆) megavitaminosis (over 2 g daily) has been reported to produce progressive sensory ataxia, which improves after discontinuation of the drug.* We describe patient who had the typical picture of pyridoxine-induced ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I-cell disease, or mucolipidosis II, is a lysosomal disease of autosomal recessive inheritance. Affected newborns have gingival hypertrophy and Hurler's-syndrome-like skeletal malformations. Progressive joint dysfunction, psychomotor ...

To the Editor: Haloperidol is the current treatment of choice for Tourette's syndrome.¹ However, the reduction of motor and vocal tics in response to this nonspecific dopamine-receptor blocker is often limited by adverse effects, which can prevent ...

No extract is available for articles shorter than 400 words.

To the Editor: In view of the long, arduous, and expensive training required to become a physician, one would not expect doctors to discriminate against their colleagues because of age.

It is therefore disconcerting to note that applicants for the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

One of the memorable advances in the relief of suffering took place in Boston on October 16, 1846. It was justly celebrated as the first public demonstration of the use of ether for anesthetization during the course of a surgical operation. As a result, ...

Edited by Jay R. Harris, Samuel Hellman, and William Silen. 348 pp., illustrated. Philadelphia, J.B. Lippincott, 1983. $45.

This work assembles the evidence that local excision of breast carcinoma, with or without axillary-node biopsy, is therapeutically ...

The first book listed above covers selected topics in the field.

Prognosis and treatment in breast cancer can only be improved by a better understanding of its biology. Several chapters in this book are comprehensive reviews devoted to that goal. The ...

Edited by Catherine H. Pfeiffer and John B. Mulliken. 239 pp., illustrated. Reston, Va., Reston, 1984. $14.95.

This multiauthored book is based on an annual continuing-education program on breast cancer conducted for nurses and other health-care ...

This book is deceptive. The title itself would not seem to indicate a particularly interesting topic. The slimness of the book suggests a superficial treatment. But this is not true. The book becomes increasingly interesting as it is perused. Although the ...

This book is the product of a collaboration between a professor of health policy and management and the Insurance Institute for Highway Safety. It thoroughly documents the magnitude and importance of injuries in the United States. While pointing out that ...

In this short book the authors present a survey of clinical experience with the use of the carbon dioxide laser in over 3000 surgical operations carried out at Tel Aviv University, principally in the Department of Plastic and Maxillofacial Surgery. They ...

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

RUSH–PRESBYTERIAN–ST. LUKE'S MEDICAL CENTER

The Center will hold its 11th annual course on Computed Tomography and Magnetic Resonance Imaging of the Brain, Head, Neck, and Spine at the Chicago Marriott Hotel, November 1 and 2. The fee is $360.

Contact Dr. ...