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February 23, 1984  Vol. 310 No. 8

Original Articles
477-482

DEVELOPMENT of lymphoreticular neoplasia is an important complication of immunosuppressive therapy in recipients of organ transplants.1 2 3 Previous studies from our institution have shown that the development of a lesion closely resembling that of ...

483-488

    RANDOM fluctuations in the motor performance of patients with Parkinson's disease who are receiving levodopa therapy are a major problem in the long-term management of the disorder. Some fluctuations are related to the timing of drug administration. Peak ...

    488-491

    LICHEN sclerosus is a chronic cutaneous disorder that may affect any skin area in any race, at any age, and in either sex.1 2 3 Most commonly, however, it occurs on the vulva in postmenopausal white women. Untreated, the condition is progressive and ...

    492-497

    THE acquired immunodeficiency syndrome (AIDS) is known to occur among homosexual or bisexual men, intravenous-drug abusers and their infants, female sexual partners of men with the syndrome, Haitians, and patients with hemophilia.1 In a preliminary report ...

    497-500

    FOR many years leptospirosis has been recognized as an occupational hazard of U.S. soldiers training in the Republic of Panama.1 In 1981 and 1982, several large outbreaks of this disease occurred among soldiers training during the fall. Attack rates ...

    Special Article
    501-504

      SELECTIVE abortion because of serious fetal disease or defect is currently practiced in many hospitals during the first and second trimesters of pregnancy. However, after 24 weeks of gestation, when the probability of extrauterine survival increases, ...

      Medical Progress
      504-511

        DURING the past 10 years, investigators of radiation-induced carcinogenesis in human beings have concentrated on continuing the follow-up of populations previously studied and on collating and reanalyzing all available data. Although these approaches may ...

        Case Records of the Massachusetts General Hospital
        512-520

        Presentation of Case

        A 70-year-old woman was admitted to the hospital because of dyspnea.

        She was well until 46 years earlier, when bilateral thrombophlebitis developed, and ligation of the inferior vena cava was performed. Persistent peripheral edema ...

        Editorials
        521-523

        The ability of the immune system to generate innumerable variants of the immunoglobulin structure that binds to antigen — the antibody variable region — sets it apart from all other biologic systems. How that unique diversity originates has challenged ...

        523-524

        Over the past few years important advances have taken place in the study of Parkinson's disease. Etiologic factors have been identified, new concepts and techniques have been applied to pharmacology, and innovative approaches have been adopted to ...

        524-525

        The term "leptospirosis" is now applied to diseases that may have multiple clinical presentations and are caused by any of the more than 170 serotypes of leptospires, of which at least 27 occur naturally in the United States. Leptospirosis occurs ...

        Correspondence
        525-526

        To the Editor: A case of equine rabies has recently been detected in southeastern New Hampshire. This event is of considerable interest because equine rabies has not been reported in New England in recent years. It is also distinctive in that the need ...

        526

        To the Editor: On a pharmacokinetic basis and as a function of their plasma half-lives, benzodiazepines have been divided into two groups; short-acting (such as oxazepam, lorazepam, temazepam, and triazolam) and long-acting (such as chlordiazepoxide, ...

        527

        To the Editor: Cyclosporine has proved to be a useful drug in the prevention of graft rejection after solid-organ transplantation1 2 3 and is effective in the prevention of graft-versus-host disease after bone-marrow transplantation.4 Renal5 , 6 and ...

        527-528

        No extract is available for articles shorter than 400 words.

        528-529

        To the Editor: Beutler et al. studied 110 nonobese but only 27 obese subjects, and all but three of them were white (Sept. 29 issue).1 The author's main conclusion that there was no difference in erythrocyte sodium-potassium-ATPase levels between obese ...

        529-530

        No extract is available for articles shorter than 400 words.

        530

        To the Editor: The Sounding Board article by Dr. Hilfiker1 and the discussion it stimulated2 clearly showed that there are no easy answers to questions of medical care for elderly debilitated patients. The decisions concerning care of a terminally ill ...

        530-531

        To the Editor: There are accepted criteria for quality control that are used to maintain and assess the reliability of diagnostic procedures, including radioimmunoassays. Most commercial kits and research-laboratory immunoassays for parathyroid hormone ...

        531-532

        To the Editor: Medical-school courses in gross anatomy have been the subject of numerous discussions regarding their relevance, content, length, and format.1 2 3 Of perhaps more immediate importance is the physical environment in which such courses are ...

        532

        No extract is available for articles shorter than 400 words.

        532-533

        No extract is available for articles shorter than 400 words.

        533-534

        To the Editor: As a primary-care physician serving as a provider with the Arizona Health Care Cost Containment System (AHCCCS) since its inception over a year ago, I would like to share some personal insights. I agree with Dr. Vogel (Oct. 13 issue)* that ...

        534

        No extract is available for articles shorter than 400 words.

        534

        No extract is available for articles shorter than 400 words.

        Book Reviews
        534-535

        There has been an explosive increase in our knowledge of human viral hepatitis during the past two decades. The protean nature of viral hepatitis is such that the application of these new discoveries touches all aspects of basic and clinical science. The ...

        535

        No extract is available for articles shorter than 400 words.

        535

        Even before recognition of the acquired immunodeficiency syndrome (AIDS), the increasing prevalence and diversity of sexually transmitted infections in homosexual men had become a major public-health problem. At least in part, inadequate education of ...

        535-536

        With the growth of literature in immunology and allergy, attempts to blend these two disciplines have appeared in several publications, of which these two are examples. These two books are designed for the primary-care physician with an interest in common ...

        536

        No extract is available for articles shorter than 400 words.

        536

        The multiplicity of organ involvement and the diversity of symptoms in patients with systemic lupus erythematosus and the variable course of these patients present a major challenge both to the clinician and to any author attempting to describe the ...

        537

        No extract is available for articles shorter than 400 words.

        537

        The idea behind this small, relatively cheap, and attractive paperback is to provide an introductory textbook for medical students studying histology. It stresses common recurring patterns in cells and tissues, the meaning of these patterns, and the ...

        Books Received
        537-538

        The receipt of these books is acknowledged, and this listing must he regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

        Addresses of most overseas publishers ...

        Notices
        538-539

        BOSTON COMPUTER SOCIETY

        The medical/dental group of the Boston Computer Society will meet in the IRC center (third floor), Minuteman Technical High School, Lexington, Mass., on Monday evening, February 27, at 6:30. The meeting will deal with word ...

        Health Policy Report
        539-544

        The federal government has long engaged in a political balancing act to accommodate the conflicting forces that debate the shape of public policies affecting the use of tobacco in the United States. The contradictions in federal policies are striking: the ...

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