NECROTIZING fasciitis is a rare but often fatal soft-tissue infection primarily involving the superficial fascia and resulting in extensive undermining of surrounding tissues. Skin is initially spared, but as the necrotizing process spreads, all the soft-...

OSTEOGENESIS imperfecta is the most common heritable disorder of bone and is often regarded primarily as a disorder of childhood. However, many patients with osteogenesis imperfecta, particularly those with the milder variants of the condition, have a ...

WE have isolated and tested a circulating heparin-like anticoagulant from a patient with multiple myeloma (IgG₄ lambda). The anticoagulant resulted in serious clinical bleeding and contributed to the patient's death. Only one other well-defined ...

DISTURBANCES of the vestibular system are known to cause a variety of symptoms, such as dizziness, vertigo, spinning sensations, and dysequilibrium. These symptoms may appear alone or together with other symptoms to form syndromes such as Meniere's ...

CONSIDERABLE evidence indicates that patients with long-standing insulin-dependent diabetes mellitus (IDDM) may have impaired glucose counter-regulation.^{1 2 3 4 5 6 7 8 9 10} During hypoglycemia induced by intravenous injection or short-term infusion of ...

SELECTION of diagnostic studies for evaluation of the patient with angina pectoris requires an appreciation of the natural history of the patient's underlying disease. Angina pectoris is not a disease; it is a symptom that Heberden described as a "sense ...

HYPERCALCEMIA is one of the most common metabolic complications of cancer. It has fascinated clinicians since it was first recognized 60 years ago by Zondek et al.¹ It is now being recognized more commonly, as is primary hyperparathyroidism, because of ...

Presentation of Case

A 53-year-old woman was admitted to the hospital because of acute hemolytic anemia.

She was well until 101/2 years earlier, when a mass was found in the left breast. A left radical mastectomy was performed. Microscopical examination ...

A favorable outcome of necrotizing subcutaneous infections and other invasive soft-tissue infections that spread rapidly is dependent on early diagnosis followed by prompt surgical intervention to debride necrotic and infected tissue and prevent further ...

Olaus Jacob Eckman, in defending his doctoral thesis at the University of Uppsala on May 10, 1788, reported on the presence of a hereditary bone fragility, termed congenital osteomalacia, in four generations of a family living in Uppland. This was the ...

Vertigo that occurs with changes in position and is accompanied by nystagmus may result from peripheral diseases (those affecting the inner ear or eighth cranial nerve) or from central diseases (those affecting the brain stem or cerebellum). The former ...

No extract is available for articles shorter than 400 words.

To the Editor: Curran and colleagues (Jan. 12 issue)¹ incriminate transfusion of blood and blood fractions as a risk factor for acquisition of the acquired immunodeficiency syndrome (AIDS). Their evidence, although compelling, depends on an analysis that ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The account by Nathan and collaborators (Feb. 9 issue)¹ on the information value of the glycosylated hemoglobin assay in the care of patients with diabetes hardly qualifies this method as the "revolutionary advance" praised by Goldstein.²

To the Editor: We present a case of acute gastric volvulus that caused electrocardiographic changes simulating an acute inferior myocardial infarction.

An 85-year-old woman was admitted to our hospital reporting a two-hour history of incessant vomiting ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In 1926 Harvey Cushing received the Pulitzer Prize in Literature for his monumental The Life of Sir William Osler, a biography of his mentor and friend. There have been few other biographies about the man in the almost 60 years since Cushing's was ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This would appear at first blush to be the very model of a surgical monograph. Included are the medical aspects of morbid obesity and psychiatric considerations, as well as the principles, techniques, and complications of intestinal bypasses and gastric ...

To counterbalance the increasing specialization of medical practice, federal and private sources provided support about 10 years ago for programs to train primary-care physicians. Their practices were intended to focus on ambulatory-based longitudinal ...

No extract is available for articles shorter than 400 words.

Neurology and Psychiatry

Neuropathology. (The Clinical Neurosciences. Vol. 3. Edited by Roger N. Rosenberg.) Edited by Sydney S. Schochet, Jr. 572 pp., illustrated. New York, Churchill Livingstone, 1983. $85.

Neuroradiology. (The Clinical Neurosciences. ...

PSYCHIATRY AND LAW

A course entitled "Psychiatry and Law: Comprehensive Update on Controversial Issues" will be held at the Boston Park Plaza Hotel, July 12 and 13. The fee is $200.

Contact Dr. Douglas Jacobs, The Cambridge Hospital, 1493 Cambridge St., ...