THE syndrome of renal agenesis in association with malformations of other structures, lung hypoplasia, a flattened face, oligohydramnios, and amnion nodosum was reported by Potter in 1946.¹ It was shown subsequently that several of the associated features,...

HEMATURIA is a common urinary abnormality in children; screening studies in asymptomatic children have determined a prevalence of microscopic hematuria of 0.05 to 2.0 per cent.^{1 2 3} When currently recommended diagnostic tests are used, the hematuria in ...

T-lymphocytes are known to modulate IgE production in several animal models.¹ Since this antibody class is central in the pathogenesis of atopic diseases, several groups of investigators have examined whether T lymphocytes or their subsets are abnormal in ...

THE prognosis of patients with multiple myeloma that is refractory to combinations of alkylating agents and prednisone has been poor because few effective salvage treatments are available.^{1 2 3} In a recent study, a combination of vincristine, doxorubicin, ...

IMPROVEMENT of myocardial contractility through the use of positive inotropic agents is a critical component in the management of heart failure. Unfortunately, although many drugs exert cardiotonic effects in experimental studies, few of these agents have ...

THE National Surgical Adjuvant Project for Breast and Bowel Cancers (NSABP), the largest North American cooperative group dedicated to research in breast cancer, was formed in 1958 for the purpose of implementing multicenter randomized clinical trials to ...

STAPHYLOCOCCUS aureus has persisted and is now resurging as an important hospital and community pathogen.¹ In recent data gathered by the Centers for Disease Control, Staph. aureus finished second behind Escherichia coli as a cause of all types of ...

Presentation of Case

A girl was admitted to the hospital at the age of 10 years and 8 months because of episodic abdominal pain and fever.

She was in excellent health until 45 months earlier, when coryza and headache developed, followed by intermittent ...

Progress in the treatment of multiple myeloma has been disappointingly slow since the introduction of melphalan and cyclophosphamide more than two decades ago. In fact, not all patients who fulfill the minimal criteria for the diagnosis of multiple ...

IN view of the limited benefits of digitalis in the treatment of severe heart failure,¹ the search for new positive inotropic agents that are able to stimulate the depressed myocardium has become one of the major pharmacologic challenges. Preliminary ...

IN 1976 the National Surgical Adjuvant Project for Breast and Bowel Cancers (NSABP) launched a multicenter randomized clinical trial to compare mastectomy with "lumpectomy," with and without radiation, in the treatment of breast cancer. Two years later, ...

To the Editor: Ethylene dibromide (EDB) has been used for some 40 years in our country as a soil fumigant for nematode control, to protect stored grains, milling machinery, and a small percentage of citrus fruits from infestation, destruction, and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The carbohydrate content of various foods cannot necessarily be used as a reliable predictor of the glycemic response.^{1 , 2} Although studies of this effect² have examined serum glucose levels over a four-hour period following a meal, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Goldstein and Hart, in their paper in the December 15 issue,* concluded that "¹³¹I therapy for autonomous thyroid adenoma often causes hypothyroidism. . . ." In the absence of histologie or biochemical data adequately excluding coexisting ...

To the Editor: Williams et al. (Dec. 29 issue) ¹ describe a "unique" case of acquired hypoaldosteronism due to an isolated zona glomcrulosa defect. I wish to draw their attention to a 14-year-old patient we described recently who also presented with ...

To the Editor: Three years ago we described a boy with systemic carnitine deficiency in whom sustained carnitine supplementation resulted in dramatic objective and subjective clinical improvement (Dec. 11, 1980, issue.¹) We have extended the follow-up to ...

No extract is available for articles shorter than 400 words.

To the Editor: Recently, one of us (B.A.W.) was hospitalized in our teaching hospital because of a herniated intervertebral cervical disk with radiculopathy. There were no complicating conditions, and the purposes of the hospitalization were the ...

No extract is available for articles shorter than 400 words.

To the Editor: Falsification of research data and plagiarism have, one suspects, been around for some time, but only in recent years has such malfeasance generated strong public interest.

As a medical editor, my job is to help physicians in preparing the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: As of February 3, 1984, 21,801 American physicians had become members of Physicians for Social Responsibility, a nonpartisan, nonprofit organization dedicated to public education on the medical consequences of nuclear war. These and other ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Although soft-tissue sarcomas are uncommon tumors, they receive attention because the surgical resections are complex and often disfiguring. During the past 15 years, there have been increasing efforts to avoid amputation and to improve functional results ...

This book represents the culmination of the author's extensive experience with skeletal and extraskeletal sarcomas — 681 patients with soft-tissue sarcoma treated at the University of Illinois Hospital and many other patients treated at Memorial Sloan-...

No extract is available for articles shorter than 400 words.

I'his three-volume set is a comprehensive review of what was known about intiacranial aneurysms until about four years ago. (>bviously, in a work of this magnitude, one would not expect to find information thai has evolved over the past few years.

Flic ...

The receipt of these hooks is acknowledged, and this listing must lu- regarded as sufficient return for the courtesy of the sender. Hooks that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

PRIX ANDRE LICHTWITZ

The Institut National de la Santé et de la Recherche Médicale will offer the Prix André Lichtwitz in 1984 to a research worker or team of workers for outstanding research on calcium and phosphorus metabolism. The deadline for receipt ...

IN a conventionally conducted randomized clinical trial, random assignment to treatment does not lake place until the patient has been demonstrated to be eligible, has had the details of the study explained, including possible risks and benefits of the ...