THE decision to admit a patient to a coronary-care unit (CCU) for acute ischemic heart disease has serious medical and financial consequences. Typically, more than 50 per cent of patients admitted to CCUs for presumed acute ischemia turn out not to have ...

ALTHOUGH it is known that patients with the acquired immunodeficiency syndrome (AIDS) have abnormally low numbers of OKT4+ cells in their peripheral blood,^{1 , 2} it has not been established that this is the primary event in the disease. T-cell ...

ABNORMALITIES of gastrointestinal function are common in diabetes mellitus and include diarrhea, constipation, and impaired gastric emptying.^{1 2 3 4} These abnormalities are thought to be related in part to neurogenic dysfunction of the gastrointestinal ...

IT is well recognized that hyperinsulinemia may be present in some patients with diabetes. The majority of such patients have insulin resistance, demonstrated by the observation that exogenously administered insulin has reduced biologic activity.^{1 , 2} It ...

CONSIDERABLE enthusiasm has developed in recent years about the use of quantitative methods to guide the allocation of health-care resources. These approaches attempt to assign specific numerical values to the benefits of medical interventions of various ...

CORONARY-CARE units are costly facilities in which the complications of a myocardial infarction can often be prevented or effectively treated. Although two controlled trials in Britain reported no difference in outcome when selected patients with ...

AT present, the clinician has several tests available for the assessment of pancreatic function. However, many of these tests lack sensitivity or specificity or both, or are difficult to perform. Recently, an enzymatic assay kit for trypsin-like ...

Presentation of Case

A 27-year-old man was admitted to the hospital because of trauma.

He was well until 19 hours earlier, when he was involved in a motor-vehicle accident. He was taken to another hospital, where multiple injuries were found. Abdominal ...

Although my 1977 editorial¹ stressed the need for an equitable system of compensation for unavoidably injured vaccine recipients and for indemnification of physicians and manufacturers, no such general system has been adopted in the United States. We have ...

During the late 1970s, three important groups—the Association of American Medical Colleges Task Force on Graduate Medical Education, the Macy Foundation's Study Group on Graduate Medical Education, and the Graduate Medical Education National Advisory ...

To the Editor: It has been suggested that the acquired immunodeficiency syndrome (AIDS) may be caused by the "systemic release of a potent cyclosporine-like immunosuppressive molecule from a chronic fungal infection. . ." (Oct. 27 issue).¹

We have used ...

No extract is available for articles shorter than 400 words.

To the Editor: Prospect Hill virus, a Bunyavirus that is related to but distinct from Hantaan virus, the etiologic agent of Korean hemorrhagic fever, has recently been isolated from lung tissue of meadow voles (Microtus pennsylvanicus) trapped in ...

No extract is available for articles shorter than 400 words.

To the Editor: The beta-adrenergic antagonists propranolol^{1 , 2} and nadolol (Smith R: unpublished data), when given prophylactically, have been shown to reduce the frequency and intensity of headache in many patients with common or classic migraine. ...

To the Editor: Low-dose cytarabine is known to modify granulocyte maturation. At concentrations of 10^-8 to 10^-6 M cytarabine has been shown to promote terminal differentiation of myeloid leukemic cells in vitro without inhibiting DNA synthesis.^{1 , 2} An ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In the March 24, 1983, issue Girot and colleagues¹ describe two siblings with hereditary orotic aciduria and immune deficiency. They suggested that there was a relation between defects of the enzymes orotate phosphoribosyltransferase (OPRT)...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Occasionally, medical practices are inadvertently found to pose the risk of serious harm to the patients they are designed to help. Often, these are established practices that have simply not been reexamined in the light of new knowledge, and they may be ...

The first edition of this book appeared in 1980 and promptly established itself as a standard reference book of cardiovascular diseases. Rapid changes in cardiology require frequent updating, a point made by Braunwald in the preface to the second edition. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Within the past decade there has been an explosion of knowledge concerning the pathogenesis of acule myocardial ischemia and infarction. There are now incontrovertible data from numerous sources suggesting that coronary-artery spasm and thrombosis (...

No extract is available for articles shorter than 400 words.

Advances in echocardiography in the past five years have been phenomenal. Not only has the instrumentation advanced, but the addition of subcostal and suprasternal acoustic windows has improved diagnostic accuracy. In some applications, results are better ...

No extract is available for articles shorter than 400 words.

PULMONARY DISEASE

A course entitled "Cardiovascular Aspects of Chronic Obstructive Pulmonary Disease and Pulmonary Rehabilitation" will be held at the Boston University School of Medicine on June 1. The fee is $30.

Contact Barbara W. Alpert, Department of ...