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May 3, 1984  Vol. 310 No. 18

Original Articles
1137-1140

BOTH pathological1 and clinical2 3 4 5 6 7 8 9 studies have shown that during the early hours after the onset of myocardial infarction, a thrombus is usually present in the coronary artery supplying the area of necrosis. Less certain is the nature of the ...

1141-1146

THE infant with hypotonia and severe neurologic dysfunction or seizures presents a difficult and important problem in differential diagnosis. The condition may be associated with anoxic or ischemic damage, teratogenic agents, infectious diseases, ...

1146-1150

GENITAL infections from Chlamydia trachomatis are now recognized as a major public-health problem in the United States, with an incidence several times that of Neisseria gonorrhoeae.1 2 3 Both nongonococcal urethritis in men and its counterpart, ...

1150-1155

THE demonstration that electrical stimulation of the phrenic nerves resulting in rhythmic contractions of the diaphragm (pacing) could provide full-time, long-term ventilatory support to patients with quadriplegia who had respiratory paralysis was ...

1156-1161

PSORIASIS is a common skin disease that is often disfiguring and disabling. In 1974 Parrish et al.1 reported a new and effective treatment known as PUVA, which consists of orally administered methoxsalen (8-methoxypsoralen) and long-wave ultraviolet ...

Special Article
1162-1165

CLOSE observers of the health-care system, among them Arnold Relman1 2 3 and David Rogers,4 are alarmed at how fast American medicine appears to be turning from a profession into a business. The evidence of history and economics suggests that a related ...

Medical Progress
1165-1175

    IN 1953 Sanger and Thompson described the complete covalent structure of insulin, a hormone containing two separate peptide chains and three disulfide bonds.1 , 2 Although proposed models for the biosynthesis of such a complex molecule were debated for ...

    Case Records of the Massachusetts General Hospital
    1176-1181

    Presentation of Case

    A 32-year-old woman was admitted to the hospital because of proteinuria and impaired renal function.

    There was a history of episodic flank pain and fever in childhood that resolved spontaneously. As a teenager the patient experienced ...

    Editorial
    1182-1183

    Connections between industry and academic medical scientists are not new. It has long been common practice for manufacturers of pharmaceuticals and medical devices to retain the services of academic scientists as consultants or to subsidize their research ...

    Editorial Retrospective
    1183-1185

    The year 1983 marked the 10th anniversary of the introduction of computed tomography (CT) in the United Slates. In 1978 this diagnostic technique was still the focus of intense controversy,1 , 2 primarily because of its cost. Considered by physicians to ...

    Massachusetts Medical Society
    1185

    DEATHS

    Gordon — George Samuel Gordon, M.D., of Lynn, died on February 5. He was 70.

    Dr. Gordon graduated from Middlesex University School of Medicine in 1937. He was a member of the American Medical Association and the American Academy of General ...

    Correspondence
    1186

    No extract is available for articles shorter than 400 words.

    1186-1187

    No extract is available for articles shorter than 400 words.

    1187

    To the Editor: Coronary-artery dissection is a rare complication of cardiac catheterization and is associated with morbidity and mortality.1 2 3 4 We report a case of extensive acute left-coronary-artery dissection treated with intracoronary ...

    1187-1189

    To the Editor: There have been fundamental changes during the past 15 years in the investigation and certification of death in Minnesota. Two of these changes, due to the gradual development of modern forensic systems for investigation of death in five ...

    1189

    No extract is available for articles shorter than 400 words.

    1189-1190

    To the Editor: Several months ago the medical staff at our hospital expressed some concern regarding the results of analysis of several arterial blood-gas specimens — i.e., the results were inconsistent with the patients' status. Specifically, the ...

    1190

    To the Editor: According to a current hypothesis, potassium wasting in Bartter's syndrome is caused primarily by a defect in the active reabsorption of chloride in the ascending segment of the loop of Henle, with ensuing increased distal tubular flow.1 ...

    1190-1191

    No extract is available for articles shorter than 400 words.

    1191

    To the Editor: There has been recent interest in the possibility that studies of cation transport in blood cells might reveal the presence of alterations that would serve as genetic markers for essential hypertension. One such pathway, sodium–lithium ...

    1192-1193

    To the Editor: Schafer et al. (Nov. 17 issue)1 conclude that "gastric cancer is no more common among patients with prior gastric surgery for peptic-ulcer disease than among members of the population at large." We are uncomfortable with this conclusion.

    ...

    1193-1194

    To the Editor: During the past five months we have encountered angiolipomas, an uncommon variant of benign adipose tumors,1 2 3 in seven young homosexual men (Table 1).

    All the lesions were subcutaneous masses of recent onset, and except in Patient 7, ...

    1194

    No extract is available for articles shorter than 400 words.

    1194

    No extract is available for articles shorter than 400 words.

    1194-1195

    No extract is available for articles shorter than 400 words.

    1195-1196

    No extract is available for articles shorter than 400 words.

    1196

    No extract is available for articles shorter than 400 words.

    Book Reviews
    1197

    It is only in the past decade that neurobiology has matured sufficiently to stand on its own as a subdiscipline of biology. With the recent growth in neurobiologic information, several institutions (particularly medical schools) have begun to treat this ...

    1197

    The author states in his preface that because too little time is now spent in physiology courses, "this text is an attempt to explain in writing what I should have taught my students, if we had the time." Although it was written for medical students, he ...

    1197-1198

    It is traditional among medical researchers to preface any discussion of their own specialty with remarks about the magnitude of the health problem it poses, and to close with a plea that their field be accorded a higher priority and more generous ...

    1198

    This is a book by two sociologists about the experience of living with epilepsy as an illness as distinct from epilepsy as a disease. The authors make the sociologic distinction that illness as a concept carries with it the full psychological, social, ...

    1198-1199

    No extract is available for articles shorter than 400 words.

    1199

    The difficulty of introducing students to psychiatry has continued to provoke innovative literary and pedagogical efforts. These have ranged from the use of biography, literature, and drama to illustrate aspects of psychopathology and adaptation, to ...

    1199-1200

    The biologic basis and drug treatment of both schizophrenia and affective disorders represent a vast topic; to review what is known in under 400 pages is an ambitious task. This new book does a very good job of condensing a great deal of information into ...

    Books Received
    1200

    Surgery

    Atlas of Hand Surgery. Vol. 2. By Robert A. Chase. 480 pp., illustrated. Philadelphia, W.B. Saunders, 1984. $85.

    Bladder Cancer. (Butterworths International Medical Reviews. Urology 1.) Edited by Philip H. Smith and George R. Prout, Jr. 287 pp., ...

    Notices
    1200-1203

    AMERICAN CANCER SOCIETY The Society will offer a number of Research Development Program Grants for the funding of clinical studies in cancer research.

    Contact the Research Dept., American Cancer Society, 777 Third Ave., New York, NY 10017; or call (212) ...

    Health Policy Report
    1203-1208

    The drive to transform the traditional method of delivering medical care through the creation of alternative modes, which usually feature some limitation on a patient's choice of physicians in return for comprehensive medical benefits provided at a fixed ...

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