PROSTACYCLIN is a vasodilator compound that potently inhibits platelet function and is the principal metabolite of arachidonic acid formed by vascular endothelial cells.^{1 , 2} Attempts to measure prostacyclin biosynthesis in vivo have focused on ...

FUNCTIONAL hypothalamic amenorrhea is a common cause of female infertility in which anovulation is associated with low or apparently normal gonadotropin levels and normal prolactin levels, without evidence of a structural pituitary or hypothalamic lesion. ...

STUDIES have found a direct association between parental smoking status and illness of the lower respiratory tract, as well as chronic middle-ear effusion, in young children.^{1 2 3 4} These investigations, combined with our well-established knowledge of the ...

ALUMINUM intoxication has been implicated in the pathogenesis of dementia,¹ microcytic anemia,² and osteomalacia^{3 , 4} in patients undergoing maintenance hemodialysis. The osteomalacia syndrome is characterized clinically by myopathy, bone pain, pathologic ...

FREE cytosolic calcium in large measure determines the development of tension in vascular smooth-muscle cells and hence arteriolar resistance.¹ An increase in intracellular free calcium may result from enhanced influx — e.g., through slow calcium channels,...

ONE of three patients who die at the Beth Israel Hospital undergoes cardiopulmonary resuscitation.¹ The question of who should decide whether to perform or withhold resuscitation was once easily answered: the physician made the decisions about life and ...

NECROTIZING enterocolitis is the most common acquired gastrointestinal emergency in the neonatal-intensive-care unit.^{1 , 2} Its initial clinical manifestations may be indistinguishable from those of sepsis neonatorum. Necrotizing enterocolitis is suspected ...

Presentation of Case

A 74-year-old man was admitted to the hospital because of dyspnea and bilateral pulmonary infiltrates.

He was well until 25 months earlier, when he was seen at another hospital because of painful knees. Laboratory studies showed ...

With the advent of long-term hemodialysis therapy it was anticipated that the symptoms of uremia would be modified and new diseases might occur simply as a result of prolonging a modified uremic state by artificial means. The first new disease discovered ...

The weight of recent opinion, as well as a new body of law, supports the rights of competent adults to have information about their medical condition and to participate in decisions concerning their health.^{1 2 3 4 5} This is not to say that patients are ...

IN my lifetime, medicine and the illnesses we physicians are asked to treat have changed greatly. Many of the past scourges have gone, yet we seem to be faced not with fewer problems but with more and more. I will comment about some of these problems and ...

No extract is available for articles shorter than 400 words.

To the Editor: Herpes zoster ophthalmicus is a disease primarily affecting the elderly during the sixth and seventh decades of life.^{1 2 3} Between October 1982 and September 1983, we evaluated 25 consecutive cases of herpes zoster ophthalmicus (defined by ...

No extract is available for articles shorter than 400 words.

To the Editor: Pape et al. (Oct. 20 issue)¹ report 16 cases of Kaposi's sarcoma and 46 cases of opportunistic infection occurring in 61 Haitians from June 1979 to October 1982. The authors state that of the 46 cases of opportunistic infection, 31 "met ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The National Health and Nutrition Examination Survey, analyzed by Annest et al. in the June 9 issue,² was a fine piece of opportunistic research. During the course of one survey another objective was fulfilled — namely, the estimation of ...

To the Editor: Sackett and his co-workers recently reviewed nine publications related to the phenomenon of labeling hypertensive patients (Nov. 17 issue), and concluded with an apparent paradox. Hypertension-screening programs that contact the smallest ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As cardiopulmonary resuscitation (CPR) becomes routine for in-hospital deaths unless it is explicitly countermanded for cause, justification for the procedure is being inspected from many points of view. In an excellent review of the literature up to 1980,...

This seems to be a time for institutional histories. There is no major war going on; the "crisis" in health care seems to be perpetual; there is a pervasive sense of change that is often seen as a clouded and ominous future. It is a time of stock-taking, ...

The Physician's Covenant offers a refreshing approach to ethics in medical practice. The author examines five images of the healer that describe the fundamentally moral nature of professional relationships. According to May, these images provide a "...

Consumerism and the development of a negotiation/accommodation model of shared power in medicine, as compared with the traditional physician–patient relationship defined by the physician's prestige and dominance, is a real, important, and growing modern ...

In this book the author examines health, illness, and healing and highlights certain aspects that should be important to all who care for the sick. Medicine is first placed in its historical context, with roots common to magic, mythology, and religion. In ...

It is doubtful whether any medical school in the United States has survived as many difficulties and accomplished as much as Meharry has during its first 100 years. This history has been documented in scholarly fashion in a book that should attract the ...

A combination of forces, including public and private third-party payers, informed consumers, the courts, and health professionals, pushes harder than ever today for a level of medical care that is at least reasonably acceptable, if not optimal. Ethical, ...

As the urgent need to control the nuclear-arms race becomes more compelling, it is important to have easily available the most meaningful evidence on the devastating effect of a nuclear explosion. Especially needed is evidence of the prevailing ignorance, ...

Physicians throughout the world are increasingly involved in decisions related to nuclear war. In the United States, for example, physicians are being asked to participate in civil-defense planning and in a system for handling the overflow of casualties ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

DERMATOLOGY

A course entitled "Dermatology for Non-Dermatologists" will be held at the Myrtle Beach Hilton in Myrtle Beach, S.C., June 27–30. The fee is $350.

Contact "Dermatology for Non-Dermatologists," P.O. Box 2987, Duke University Medical Ctr., ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.