IN populations prone to coronary heart disease, there is an inverse association between levels of plasma high-density-lipoprotein (HDL) cholesterol and coronary disease. An increased occurrence of disease is associated with reduced levels of HDL ...

RAISED levels of growth hormone have long been recognized as a characteristic feature of poor diabetic control^{1 2 3 4} and have been implicated in the pathogenesis of diabetic microangiopathy.⁵ Yet, despite evidence that growth hormone is an insulin ...

AGING decreases hormone responsiveness in several receptor systems.^{1 , 2} This also occurs in the β-adrenergic receptor system,^{3 4 5 6} as reflected by the smaller isoproterenol-induced increase in heart rate in the elderly.^{7 , 8} This alteration may have ...

SINCE its development in the early 1960s,^{1 , 2} coronary arteriography has occupied a position of foremost importance in the assessment of patients with coronary-artery disease. Despite shortcomings in interpretation due to interobserver and intraobserver ...

KNOWLEDGE about illness and its relations to the use of health services has been derived primarily from studies of particular health problems, generally over relatively short periods. As patterns of illness are altered as a result of social and ...

THE β-adrenoceptor antagonists have been shown to be both safe and effective for the treatment of systemic hypertension, arrhythmia, angina pectoris, hypertrophic cardiomyopathy, thyrotoxicosis, and open-angle glaucoma, and for prophylaxis against ...

IN 1953 Poulsen described a patient with diabetes mellitus in whom retinopathy was ameliorated after postpartum pituitary infarction.¹ He pointed out the possible analogy of the events in his patient to the observation of Houssay that experimental ...

Presentation of Case

A 31-year-old man was admitted to the hospital because of fever and a pelvic mass.

He was in excellent health until three months earlier, when malaise and a low-grade fever developed, followed by anorexia and intermittent diarrhea. ...

Throughout the history of humanity, alcoholic beverages have been widely used for their pleasing taste and their mood-altering effects. However, the use of alcohol has evoked strong opposition, because of the potential for abuse and the associated adverse ...

Numerous studies of both laboratory animals and human beings have implicated poor glycemic control as a risk factor for development of the so-called long-term complications of diabetes mellitus (neuropathy, nephropathy, retinopathy, and premature ...

How can a patient with advanced atherosclerosis, including a total coronary-artery occlusion, have normal cardiac function? The answer involves the complexities of the relation between coronary-artery anatomy and coronary physiology in ischemic heart ...

No extract is available for articles shorter than 400 words.

To the Editor: In their well-executed prospective matched study, (Nov. 3 issue),¹ Dr. Giagnoni et al. suggest that "the exercise EKG [electrocardiogram] is an independent coronary risk indicator, with a role additional to that of the conventional risk ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The most dramatic scientific advances in clinical obstetrics have concerned the second half of pregnancy. Yet, divisions such as "early" and "late" pregnancy are artificial, since it is obvious that fetal growth and development are a dynamic continuum.

As ...

In his foreword Louis Gluck states: "Unfortunately there are significant numbers of newborns who are born imperfect. They may be victimized by many mechanisms: infectious agents, inherited defects and conditions, trauma, decreased intervillous blood flow, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The shift in place of birth from home to hospital is a striking example of the ways in which technology has affected medical practice. Most members of the population over the age of 50 were born at home. The Boston Lying-in Hospital discontinued its home-...

We live in a new era of physician–patient relationships. Patients are demanding to know more and are increasingly litigious when outcomes are not perfect. One way to improve the relationship between patient and physician is to involve patients more fully ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

SEVENTH ANNUAL PAGE LECTURE

The Seventh Annual Page Lecture, entitled "Basic Science and Clinical Medicine: Problems and Opportunities at the Interface." will be held at the Cleveland Clinic Foundation, in Cleveland on April 18.

Contact Mrs. Kathleen ...

Congress, driven by an emotional desire to provide lifesaving therapies to children afflicted with liver disease and by legislators who believe that government should intervene more aggressively to help, is moving rapidly to enact legislation aimed at ...