THE solitary autonomous thyroid nodule is "a discrete nodular structure with function both independent of pituitary stimulation and unrelated to that of the remaining thyroid tissue."¹ It is also known as the "hot" thyroid nodule, or toxic adenoma.

Toxic ...

CORONARY angiographic studies during the early hours of acute myocardial infarction have usually demonstrated coronary-artery thrombosis.¹ Studies employing coronary-artery ligation in laboratory animals suggest that early reperfusion can limit the extent ...

VASOACTIVE intestinal polypeptide (VIP) has been implicated in the pathogenesis of watery diarrhea in pancreatic cholera, or Verner–Morrison, syndrome.^{1 2 3 4 5} Several lines of evidence suggest a pathogenic role for VIP in pancreatic cholera syndrome: (1)...

CONGENITAL hypoplastic anemia, also known as the Diamond–Blackfan syndrome, characteristically presents as hypoplastic macrocytic anemia in the first year of life.^{1 2 3 4 5 6} The variable clinical course of Diamond–Blackfan syndrome is characterized by ...

DURING the past decade, the care of the terminally ill has become a topic of sharpened debate. The conditions under which people die, the attitudes and practices of the medical profession toward them, and the ability of dying patients to control or modify ...

DURING the course of efforts to determine the distribution of growth hormone–releasing factor (GHRF) in rat hypothalamus, a substance that inhibited growth hormone release was unexpectedly detected by Krulich et al.¹ Their findings, reported in 1968, led ...

Presentation of Case

A 72-year-old woman was admitted to the hospital because of a pulmonary infiltrate.

She was well until two years earlier, when a cough productive of yellow sputum developed and resolved after the administration of penicillin. Four ...

In the United States, thyroid adenomas that function independently of thyroid-stimulating hormone (known as autonomously functioning thyroid adenomas) are uncommon. They may produce amounts of hormone less than or approximately equal to normal ...

The intestinal tract is the most powerful secretory organ of the human body. An adult with cholera, for example, may excrete more than 1 liter of fluid per hour. The offending organism in cholera elaborates an enterotoxin that attaches to intestinal ...

IN 1977 an article in the Journal ¹ reported that aspirin prophylaxis (600 mg twice daily) was effective against the development of postoperative venous thrombosis and pulmonary embolism in patients who had undergone total hip replacement. Postoperative ...

No extract is available for articles shorter than 400 words.

To the Editor: Cimetidine is known to be a clinically important inhibitor of drug metabolism because of its interaction with microsomal monooxygenases.¹ A study was undertaken to determine whether cimetidine might affect the disposition of metronidazole ...

To the Editor: According to current recommendations, persons at high risk of contracting type B hepatitis should be screened for antibody to hepatitis B surface antigen; those whose serum is found to be nonreactive for the antibody should receive ...

To the Editor: With respect to the papers by Krakauer et al. and Vollmer et al. on survival with end-stage renal disease (June 30 issue),^{1 , 2} we are concerned about what happened to the patients with transplants that failed. Although such patients may ...

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To the Editor: The finding of chromosomal translocations in Ewing's sarcoma cell lines^{1 2 3} invites comparison with other tumors of the young associated with chromosomal deletions — in particular retinoblastoma with 13q- and Wilm's tumor with 11p. On ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

For various reasons there seems to be increasing dissatisfaction with certain aspects of conventional or orthodox medicine. As Dr. Tony Smith has pointed out in the British Medical Journal,¹ one of the few growth industries in contemporary Britain is what ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This is a good reference book. It is well written, magnificently illustrated, and current in its references, with several as recent as 1982. The majority of the chapters are both comprehensive and well written. As can be expected in a multiauthored book ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Soft-tissue tumors are a diagnostic challenge for the anatomical pathologist. Their morphologic features are indistinct, their degree of malignancy is difficult to evaluate, and many of these lesions occur so infrequently that the experience of one ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This author, a nuclear physicist who has spent most of his life performing basic research in nuclear physics, has become concerned with the safety factors provided for nuclear reactors. He states that although he has no professional connection with ...

Biomedical Science

Advances in Cancer Research. Vol. 39. Edited by George Klein and Sidney Weinhouse. 343 pp. New York, Academic Press, 1983. $46.

Animal Models for Oral Drug Delivery in Man: In situ and in vivo approaches. Edited by William Crouthamel ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.