Many anticancer agents are known carcinogens. There is increasing awareness that the chemotherapy or radiotherapy used to induce a long-term complete remission of one cancer may induce a second cancer. Certain drugs and drug combinations have been ...

The survival of children with acute lymphocytic leukemia (ALL) has improved dramatically in the past 15 years, so that over half may be cured. This improvement has been due to the use of Central-nervous-system "prophylaxis" as well as effective systemic ...

Recent technologic advances, coupled with the premise that improved metabolic control may delay or prevent the complications of diabetes, have led to widespread enthusiasm for intensive forms of therapy in insulin-dependent patients with diabetes ...

Major Environmental Causes (Cont.'d)

Occupational Hazards

As the discussion in Part 1 indicated, there has been only limited success in identifying environmental chemicals that may be causing human congenital malformations. It has been reasoned that the ...

For a century the early diastolic sound — called the third heart sound (S3) or ventricular diastolic gallop — has been attributed to left ventricular vibrations caused by rapid ventricular filling in early diastole.^{1 2 3} It has therefore been generally ...

AT least 15 per cent of all married couples are involuntarily infertile.¹ During the past several decades, infertility due to peritoneal and endocrine factors has received the greatest attention, and specific treatments for many of these causes are now ...

The role of T mycoplasma (Ureaplasma urealyticum) in reproductive failure is controversial. Since mycoplasma was first isolated from a genital-tract abscess,¹ an association between mycoplasma and various genital-tract conditions, reproductive failure, ...

The obstructive sleep apnea syndrome is a recently described clinical disorder that results from repetitive episodes of upper-airway occlusion during sleep.¹ Since the syndrome occurs much more frequently in males than females,² it is reasonable to ...

Presentation of Case

A 60-year-old man was admitted to the hospital because of increasing dyspnea.

He was well until five years earlier, when angina pectoris developed. Thirty-nine months before admission the angina became more severe, and propranolol was ...

IN 1977, Stockman et al. measured erythropoietin levels in the plasma of 45 premature infants by means of a radioimmunoassay developed in the laboratory of Dr. Joseph Garcia.¹ They found that the hemoglobin concentration or the oxygen-releasing capacity ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Burroughs Wellcome has announced the availability of digoxin in a new dosage form: digoxin solution in soft gelatin capsules. Marketed under the trade name Lanoxicaps, these capsules are available in 0.05-mg, 0.1-mg, and 0.2-mg strengths. ...

To the Editor: The Hypertension Detection and Follow-up Program (HDFP) Cooperative Group reports reduced total mortality in a group of patients with mild hypertension (diastolic blood pressure, 90 to 104) who were randomized to receive free, very ...

To the Editor: A 59-year-old hemodialysis technician with underlying cardiac valvular disease presented with staphylococcal endocarditis. This technician had been part of a microbiologic surveillance program. Weekly nasal and skin cultures had been ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recently we described the clinical and hematologic features of sickle-cell disease in adult patients who also had iron-deficiency anemia due to blood loss.¹ We now report the results of red-cell-survival studies that were carried out in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: One wonders whether Dr. Siddiqui describes the sense of taste as unnecessary on the basis of his own experience or merely that of his patients (Oct. 7 issue).* Having recently undergone radiation therapy to my neck and left pharynx, I have ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Since the last London Post was written over two years ago,¹ the British medical scene has been unsettled on account of economic factors, government policy, and professional problems.

Whether the so-called monetarist policy of the Thatcher government is ...

The Sidels' new book on medical care in China, like that of Butterfield on the broader culture, reveals its topic in a more realistic and less romantic light than most of the recent literature available to readers in the West. Swings in Western ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The subtitle of this book — "How illness affects literature, art and music" — immediately challenges the prospective reader. In a flash, some well-known examples come to mind: Van Gogh in painting, Blake or Plath in poetry, and DeQuincey in prose (Oh my! ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Hooks that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of new ...

MEETING OF THE AMERICAN ORTHOPSYCHIATRIC ASSOCIATION

The 60th annual meeting of the Association will be held at the Boston Park Plaza Hotel, April 4–8. The fee is $95.

Contact The American Orthopsychiatric Assoc., 1775 Broadway, New York, NY 10019; or ...

On October 1, 1982, Chapter 372 of the Massachusetts Legislative Acts of 1982, governing how each of the commonwealth's 121 hospitals is to be paid for the next six years, became effective. The new law is intended to improve the Massachusetts health-care ...