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February 24, 1983  Vol. 308 No. 8

Original Articles
409-413

    IT is now well established that cigarette smoking increases the risk of myocardial infarction in both men and women.1 2 3 4 5 6 It is not known, however, which of the many components of cigarette smoke is responsible. It has been suggested that the ...

    414-420

    The serum of patients with systemic lupus erythematosus contains autoantibodies that react with a variety of nuclear, cytoplasmic, and cell-surface antigens.1 Lupus autoantibodies also lead to false-positive serologic tests for syphilis by reacting with ...

    420-424

    Since 1918 it has been known that patients with Graves' exophthalmos have abnormal elevation of intraocular pressure.1 Not until 1953, however, was it recognized that such patients typically have normal intraocular pressure in the primary position, which ...

    Medical Progress
    424-431

    IT is just over 20 years since an earlier review of ours of the causes and nature of congenital malformations appeared in these pages.1 When we wrote that report, teratology was a little-known branch of medicine, and the study of teratogenesis was the ...

    Medical Intelligence
    431-435

    IN most of us the the gastrointestinal tract is quiet, unobtrusive, and efficient, but it gives trouble to at least one person in three. Often symptoms are slight, and simple traditional remedies suffice. A few people experience recurrent or constant ...

    435-436

    Physicians are participating in the administration of medical and nursing-home care under Medicare and Medicaid. Much of the control over the Medicaid program is vested in the state governments Under a complex array of federal statutes and regulations.

    ...

    436-439

    One characteristic of patients with asthma is that their airways are exquisitely sensitive to a variety of inhaled stimulants. For example, their airways regularly become obstructed after inhalation of bronchoconstrictor substances at 1/100 to 1/300 of ...

    439-442

    Home treatment of classic hemophilia with lyophilized concentrates of antihemophilic factor (factor VIII) is now widely practiced. We studied a syndrome resembling chronic idiopathic thrombocytopenic purpura in five patients with severe classic hemophilia ...

    Case Records of the Massachusetts General Hospital
    443-451

    Presentation of Case

    A 51-year-old right-handed woman was admitted to the hospital because of multiple cranial-nerve palsies.

    There was a 10-year history of painless left otitis externa and media, with repeated use of eardrops. Nineteen months before ...

    Editorials
    452

    Readers will note an ad on the inside back cover of this issue announcing that beginning July 1 the Publications Committee of the Massachusetts Medical Society will use the facilities of The New England Journal of Medicine to reprint and distribute the ...

    453-454

    Soft-tissue swelling that would be innocuous in many locations has serious effects where local anatomy confines the swelling tissues within an inexpansible space. The anterior-tibial-compartment and carpal-tunnel syndromes are good examples of such ...

    454-456

    Nowadays, bronchial asthma is generally regarded as a disease of allergy. Its expression can be attributed to a constitutional predisposition which not only manifests itself as a hypersensitivity to various allergens, but also as an altered resistance of ...

    456-458

    The more severe forms of β-thalassemia, which are among the commonest single-gene disorders in the world, are particularly distressing, because affected children who receive adequate transfusions grow and develop normally, only to die of cardiac failure ...

    Correspondence
    458

    To the Editor: The estimate given by Nashel et al. of the average radiation dose from older color television sets (Sept. 30 issue)1 is erroneous and misleading. The average dose is 100 to 200 times lower than their estimate. In calculating average annual ...

    458-459

    No extract is available for articles shorter than 400 words.

    459

    No extract is available for articles shorter than 400 words.

    459-460

    No extract is available for articles shorter than 400 words.

    460-461

    No extract is available for articles shorter than 400 words.

    461

    No extract is available for articles shorter than 400 words.

    461-462

    To the Editor: The paper by Rapoport et al. (Oct. 7 issue) 1 prompts us to describe our experience with nasal continuous positive airway pressure for treatment of severe obstructive sleep apnea. Following the approach of Sullivan et al.,2 we have applied ...

    462

    No extract is available for articles shorter than 400 words.

    463

    To the Editor: Ectopic ACTH production is one of the most frequent endocrine syndromes caused by "nonendocrine" tumor tissue. The most frequent cause is oat-cell carcinoma of the lung. The second most common cause is carcinoid. We report here an unusual ...

    463

    No extract is available for articles shorter than 400 words.

    464

    No extract is available for articles shorter than 400 words.

    464-465

    To the Editor: A 1978 editorial in the Journal expressed "reasonable doubt" about pertussis vaccine.1 One reason for doubt was the absence of reliable data about the prevalence and pattern of whooping cough. This gap is now filled by a supplementary ...

    465-466

    No extract is available for articles shorter than 400 words.

    Book Reviews
    466

    This remarkable book is really two volumes in one. The first half is a social history of the medical profession in America, starting in Colonial times and continuing into the mid-20th century. The second part traces the convoluted story of health-care ...

    466-467

    Several economic, demographic, and clinical studies over the past decade have fueled the "therapeutic nihilism" view that medical care makes little or no positive contribution to the health of the population. This book, the report of a detailed ...

    467

    In the debate over the cost and quality of American medical care, the surgical disciplines have probably attracted more than their fair share of criticism. In the early 1970s, highly publicized allegations about the extent of unnecessary surgery in the ...

    467-468

    The authors of any book on rural medical care are faced with a formidable task. Rural medical care is as diverse as rural America. Although there are some constants, rural communities often have more in common with a city in the same region than with a ...

    468

    This book will be perceived as a political statement, whether or not the authors intended it as such. Its purpose is not only to educate but to serve as a guide for women in their effort to deal with the "health-care establishment." How the reader reacts ...

    468-469

    No extract is available for articles shorter than 400 words.

    Books Received
    469-470

    The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Hooks that appear to be of particular interest will be reviewed as space permits.

    Addresses of most overseas publishers ...

    Notices
    471-472

    PROGRAMS OF THE SOUTHERN MEDICAL ASSOCIATION

    The Association will offer two programs in the coming months: a "Medical Staff Leadership Seminar" (March 18–20, in Sarasota, Fla., and April 22–24, in Hilton Head, S.C.); and a "Regional Postgraduate ...

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