TOXICITY associated with high levels of lead in the body has long been recognized. Recently, however, investigators conducting biochemical and epidemiologic studies have noted hematologic and neurologic damage in children with relatively low levels of ...

CLINICIANS, patients, their families, and society would all benefit from accurate predictions of neurologic recovery after cardiac arrest. Previous studies relating predictors and neurologic outcomes of cardiac arrest have suffered from small sample sizes,...

GROUP B streptococcal disease continues to be one of the most common infectious causes of morbidity and mortality in the neonatal period.^{1 2 3 4} The incidence of early-onset disease ranges from 1 to 4 per 1000 live births.⁵ The incidence of the disease ...

REPEATED observations that breast-fed infants have a lower incidence of enteric infections than bottle-fed infants have promoted an intense effort to identify the protective properties present in breast milk.^{1 2 3 4 5} More than 10 different factors have ...

THE widespread availability of factor VIII and factor IX concentrates for patients with classic hemophilia (also known as factor VIII deficiency or hemophilia A) or Christmas disease (factor IX deficiency or hemophilia B) in conjunction with the education ...

IDIOPATHIC thrombocytopenic purpura (ITP) is a disorder in which platelets react with an autoantibody and are destroyed by macrophages.^{1 2 3 4 5 6} Various treatments have been used. Splenectomy removes a large mass of macrophages and may also diminish ...

To the Editor: In response to the announcement by Harvard University that John R. Darsee, M.D., had fabricated research data while serving as a research fellow in their school of medicine, we initiated an extensive investigation by both internal and ...

No extract is available for articles shorter than 400 words.

It seems paradoxical that scientific research, in many ways one of the most questioning and skeptical of human activities, should be dependent on personal trust. But the fact is that without trust the research enterprise could not function. This trust is ...

Sex is a fundamental life force and may have profound effects on our behavior. It has become increasingly clear that both sex and sex hormones may modulate and alter disease in subtle yet very important ways. Sex is used by advertisers to influence our ...

THE term "immunoproliferative small intestinal disease" (IPSID) covers a variety of disorders commonly manifested by diarrhea, weight loss, abdominal pain, and clubbing of fingers and toes.^{1 2 3 4 5 6} The presenting features of the disease are attributed ...

Presentation of Case

A 63-year-old woman was admitted to the hospital because of agitation and an extrapyramidal syndrome.

She was well until 10 years earlier, when the death of her husband was followed by agitation, which improved with the administration ...

To the Editor: I agree that the papers entitled "Hypertrophic cardiomyopathy and human leukocyte antigen linkage: differentiation of two forms of hypertrophic cardiomyopathy" and "Decreased myocardial taurine levels and hypertaurinuria in a kindred with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Brittenham and colleagues recently described the use of the superconducting quantum-interference-device (SQUID) susceptometer for detecting and quantifying iron stores in the liver.¹ In an accompanying editorial,² Finch asked when ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In anesthesiology, the physician's effort is directed toward providing optimal operating conditions for the surgeon without pain, unusual hazard, or stress to the patient. Our interventions usually do not result in direct patient benefit. It is, therefore,...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This is a valuable addition to the literature of medicine, and although directed at pathologists, it may prove useful for many practicing physicians. The book opens with Irey's excellent chapter on differentiating adverse drug reactions. It then addresses ...

No extract is available for articles shorter than 400 words.

ANTIMICROBIAL CHEMOTHERAPY

A symposium entitled "Infectious Diseases in Clinical Practice: Update on Antimicrobial Chemotherapy" will be held at Snowmass in Aspen, Colo., July 3–10. The fee is $350.

Contact Extended Programs in Medical Education, School ...

The federal government, moving with unusual speed and unanimity, has enacted sweeping Medicare legislation that reverses key economic incentives that have driven the behavior of hospitals since the federal program for the elderly began 18 years ago. The ...