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May 5, 1983  Vol. 308 No. 18

Original Articles
1045-1049

ARTERIAL oxygenation and the presence of cor pulmonale, together with many other physiologic and clinical factors, are known to influence the prognosis of chronic obstructive pulmonary disease.1 2 3 4 5 6 7 In a previous study in our laboratory, we found ...

1050-1053

Hereditary angioedema is characterized by recurrent attacks of mucocutaneous swellings and abdominal pain.1 , 2 Death may result from airway obstruction.1 , 2 A biochemical abnormality was recognized in hereditary angioedema when patients with this ...

1054-1058

    Sickle-cell anemia and β-thalassemia are autosomal recessive disorders in which couples at risk have a 25 per cent chance with each pregnancy of producing an affected child. Prenatal diagnosis of these hemoglobinopathies has been carried out by analysis ...

    Special Article
    1059-1063

    Something has gone wrong in the practice of medicine, and we all know it. It is ironic that in this era, dominated by technical prowess and rapid biomedical advances, patient and physician each feels increasingly rejected by the other. Clearly, one root ...

    Medical Progress
    1063-1071

      This review discusses the rationale for vitamin E therapy in medical conditions in which the vitamin may have positive clinical effects. It should be recognized at the outset that nutritional inadequacy or frank deficiency of vitamin E is found only in ...

      Medical Intelligence
      1071-1076

      Preliminary clinical trials have shown that both natural and recombinant-DNA-produced human interferons are occasionally capable of inhibiting the growth of some tumors.1 2 3 4 Although the tumors responding to interferon have most often been those ...

      1076-1080

      Pseudotumor CEREBRI (benign intracranial hypertension), a syndrome characterized by increased intracranial pressure without focal neurologic dysfunction, occurs in association with a variety of endocrine and metabolic disorders. Thyroid disorders have not ...

      Case Records of the Massachusetts General Hospital
      1081-1091

      Presentation of Case

      First admission. A 24-year-old man was admitted to the hospital because of fever.

      The patient was malformed and mildly mentally retarded from birth; neurologic evaluation elsewhere led to a diagnosis of cerebral palsy. He resided ...

      Editorials
      1092-1094

      The physiologic derangements of patients with chronic obstructive pulmonary disease can be grouped in two categories: those that stem from the anatomic alterations produced by the disease and those that represent adaptations that, if optimally carried out,...

      1094-1095

      Sudden death from airway obstruction is a constant and dreadful threat to patients with hereditary angioneurotic edema. Patients with this disorder are subject to repeated episodes of localized noninflammatory subepithelial edema, which may be provoked by ...

      Sounding Board
      1096-1098

      Addiction is generally defined in terms of physical dependence and tolerance associated with current drug use, and these phenomena have received virtually all the attention of researchers and clinicians in the field. In fact, however, further elucidation ...

      Massachusetts Medical Society
      1098

      No extract is available for articles shorter than 400 words.

      Correspondence
      1099

      To the Editor: In their letter in the January 6 issue Snider et al. referred to cerebral lesions demonstrated on computerized axial tomographic (CAT) scans in patients with the acquired immunodeficiency syndrome (AIDS) and made the statement "biopsy of ...

      1099-1100

      No extract is available for articles shorter than 400 words.

      1100

      No extract is available for articles shorter than 400 words.

      1100-1101

      To the Editor: DiGeorge et al.1 (Dec. 9 issue) found that 24 hours after birth newborns with classic maple-syrup-urine disease had an essentially increased and diagnostically relevant plasma leucine concentration, regardless of feeding. Since all the ...

      1101

      No extract is available for articles shorter than 400 words.

      1102

      No extract is available for articles shorter than 400 words.

      1102-1103

      To the Editor: We1 2 3 and others4 , 5 have shown that the slow calcium-channel-blocking agent nifedipine is effective in the treatment of Raynaud's phenomenon. It has been suggested that in some patients vasospasm may be "ubiquitous."6 , 7 The efficacy ...

      1103-1104

      No extract is available for articles shorter than 400 words.

      1104-1105

      No extract is available for articles shorter than 400 words.

      1105

      No extract is available for articles shorter than 400 words.

      1105

      To the Editor: Increasingly, the public and physicians are concerned about smoking as the major preventable cause of illness and death in our society. In addition, in this era of cost consciousness in medicine it is important to recognize the economics ...

      1105-1106

      No extract is available for articles shorter than 400 words.

      1106

      No extract is available for articles shorter than 400 words.

      1107

      No extract is available for articles shorter than 400 words.

      1107

      No extract is available for articles shorter than 400 words.

      1107

      No extract is available for articles shorter than 400 words.

      1107

      No extract is available for articles shorter than 400 words.

      Book Reviews
      1107-1108

      No extract is available for articles shorter than 400 words.

      1108

      No extract is available for articles shorter than 400 words.

      1108

      No extract is available for articles shorter than 400 words.

      1108-1109

      No extract is available for articles shorter than 400 words.

      1109

      No extract is available for articles shorter than 400 words.

      1109

      The author states that in preparing this monograph, which "was not intended to be a textbook of cardiology," it has been his intent "to emphasize how the manifestations, pathophysiology, and treatment of heart disease differ in the elderly patient." He ...

      1109-1110

      Age-cohort medicine is as old as pediatrics. That most venerable of the age-specific fields formerly dealt with the youngest patients. It has now been undercut by neonatology and that in turn by prenatology based on amniocentesis and fetal surgery.

      At the ...

      1110-1111

      Recent dietary recommendations from federal and health agencies urge profound changes in current American eating habits. With few exceptions, they plead for the consumption of more foods containing unprocessed starch and liber (e.g., fruits, vegetables, ...

      Notices
      1111-1112

      INTERVENTIONAL ULTRASOUND

      The Third International Congress on Interventional Ultrasound will be held at Herlev University Hospital in Copenhagen, Denmark, August 30-September 2.

      Contact DIS Congress Service, Linde Allé 48, 2720 Vanløse, Denmark.

      ...

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