Congenital deficiencies of the terminal complement components have often been identified because of associated recurrent meningococcal or gonococcal infection.^{1 2 3 4} Reports of this association have documented a deficiency of C5, C6, C7, and C8 but not ...

The incidence of genital herpes simplex virus infections is now well known.¹ These infections cause appreciable acute morbidity during an initial attack. Recurrence results in additional morbidity and potential for spread of the disease.^{2 3 4 5} Since the ...

CYTOMEGALOVIRUS infections are a continuing clinical problem in immunosuppressed hosts, including those who have the acquired immunodeficiency syndrome that was first observed among male homosexual patients.¹ The increasing availability of antiviral ...

When future historians study American culture, they may be most perplexed by the explosive increase in the nonmedical use of drugs that occurred during the seventh and eighth decades of this century.^{1 2 3 4 5 6 7 8 9 10 11} This widespread increase in the ...

Biomedical Research on Malaria

The overly optimistic notion that malaria could be eradicated primarily by dichloro-diphenyl trichloroethane (DDT) spraying limited enthusiasm for basic biomedical research in malaria during the 1950s and 1960s. Few persons ...

Pindolol (Visken) is a β-adrenoceptor antagonist that was released in November 1982 for clinical use in the United States (Fig. 1). After propranolol, metoprolol, nadolol, atenolol, and timolol, it is the sixth orally active β-blocker to be approved by ...

Hermann BOERHAAVE introduced clinical thermometry into the practice of medicine in 1709, and since that time a measurement of body temperature has been included in the early evaluation of most sick patients.¹ This is because useful clues about the nature ...

THE discovery of foreign bodies in the spinal canal, coupled with an inability to learn the circumstances of their introduction, is rare, judging by the small number of published accounts.^{1 2 3} This report describes two patients — one with scissors' tips ...

Presentation of Case

A 52-year-old woman was admitted to the hospital because of multiple pulmonary infiltrates.

She was well until four months earlier, when she experienced the abrupt onset of left-sided pleuritic pain. She came to the clinic, where the ...

Ever since Wunderlich's classic monograph in 1868 on the use of the clinical thermometer, measurement of the patient's body temperature — one of the four vital signs — has become routine. Wunderlich's prophetic words are worth quoting: "The more my ...

Medicine in industrialized nations is scientific medicine. The claim tacitly made by American or European physicians, and tacitly relied on by their patients, is that their palliatives and procedures have been shown by science to be effective. Although ...

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To the Editor: The report by Baum et al. (Dec. 16 issue)* provides important evidence that long-term ambulatory peritoneal dialysis is a satisfactory method of treatment for some children with chronic renal failure. Although the authors were ...

To the Editor: Since prostaglandin E₁ improved creatinine clearance in patients with chronic glomerulonephritis,¹ we have now applied prostaglandin E₁ infusion therapy to a patient with rapidly progressive glomerulonephritis in whom impaired renal ...

To the Editor: We present here a one-center analysis of the influence of the kidney recipient's DRw6 phenotype in a population of 145 recipients whose treatment and prospective transfusion regimen have already been reported in detail.^{1 , 2} A marked ...

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What can be done to help the critically ill patient with neurologic disease? There are no counterparts to the ventilators and blood gases that are used to support and monitor physiologic function in the patient with respiratory failure, nor are there ...

One Sunday afternoon I first chanced on Blodi's recent translation of the first volume of Hirschberg's History of Ophthalmology, dealing with antiquity. Although I had other plans and priorities, I could not put the book down. Here for the first time was ...

LYME DISEASE

A symposium entitled "Lyme Disease — Pitfalls in Diagnosis" will be held in Southampton, N.Y., on May 7, 9 a.m.– 5 p.m. The fee is $35.

Contact Mr. John Pfister, Jr., Southampton Hospital, 240 Meeting House Lane, Southampton, NY 11968; or ...

As a result of the intense fiscal pressures that the states face and the federal government's new willingness to grant them broader flexibility in casting health policy, several states are moving to reshape their Medicaid programs. The clear intent of ...