Sarcoidosis is a chronic multisystem disorder characterized in affected organs by an accumulation of mononuclear inflammatory and immune effector cells, noncaseating granulomas, and derangement of normal tissue architecture.^{1 , 2} Although most organs can ...

Aspirin rapidly inhibits prostaglandin formation in vascular tissue as well as in blood platelets by inactivating fatty acid cyclooxygenase.^{1 2 3} It thereby prevents synthesis of both vascular prostacyclin — a potent vasodilator and platelet inhibitor — ...

Vasectomy has been reported to accelerate atherosclerosis in monkeys. In one experiment five vasectomized cynomolgus monkeys that were fed an atherogenic diet had more extensive atheroma at autopsy 10 months after operation than did five monkeys that had ...

Awareness of hypertension has increased substantially in the U.S. population over the past 10 years, and the range of therapeutic methods for treating hypertension has likewise increased. Nevertheless, the majority of hypertensive persons in the United ...

IT has been estimated that in a typical year Americans consume nearly 10⁹ kg of coffee.¹ In addition, large amounts of tea, cola, and other caffeinated substances are ingested.

Caffeine has long been implicated in the causation of arrhythmias, but studies ...

Dermatitis herpetiformis is characterized by an itchy blistering rash. The lesions are typically distributed over the elbows, knees, and buttocks. Histologically, the blister is situated between the epidermis and the dermis. The rash responds well to ...

Unexplained chronic generalized lymphadenopathy has recently been reported in homosexual men in several metropolitan areas in the United States.¹ Lymph-node biopsies from these patients have shown reactive lymphoid hyperplasia by light microscopy. ...

Presentation of Case

A 67-year-old woman was admitted to the hospital because of syncope on effort.

There was a four-year history of Raynaud's phenomenon, for which bilateral dorsal sympathectomies were performed two years before admission. A preoperative ...

"Bathing, exercise, fear, anger and any other state of mind may often be apt to excite the pulse," noted Celsus in A.D. 178. With the passage of nearly two milleniums, additions have been made to the list of factors that may upset the heartbeat. Clinical ...

When electron microscopy was a young discipline, excitement over newly discovered structures was universal. Descriptive names could not be coined fast enough. Many of them were cumbersome, aiming to be accurate and biochemically noncommittal. Questions of ...

The two recent descriptions in the Journal of the health-care cost-control systems in Massachusetts¹ and California² support the observation that the country is being pulled in two opposite directions at once, as frantic efforts are made to control ever-...

To the Editor: Severe acquired immunodeficiency syndrome (AIDS), associated with opportunistic infections or Kaposi's sarcoma (or both), was described in 1981 in male homosexuals from California and New York.^{1 2 3 4} Since these early reports appeared ...

To the Editor: AIDS is an entity that has recently been observed in certain groups, such as homosexuals, drug abusers, hemophiliacs, and Haitian immigrants.^{1 , 2} An agent (or agents) transmitted sexually and by blood components may be an important causal ...

To the Editor: A profound deficiency in immune function underlies the ongoing epidemic of Kaposi's sarcoma, opportunistic infection, and other disorders associated with AIDS.^{1 2 3} A major feature of the immune deficiency in AIDS is a reversal of the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I reached a different conclusion from that of Hornbrook et al. in their cost analysis of alanine aminotransferase (ALT) testing (Nov. 18 issue),* which showed that even at the low end of estimates, ALT testing would be cost effective. The ...

To the Editor: A theory implicating dopamine in psychosis and antipsychotic drug action has received a substantial amount of attention in recent years.^{1 , 2} Measurements in cerebrospinal fluid have generally failed to provide definitive evidence for a ...

To the Editor: Although antiinflammatory corticosteroids are invaluable in the treatment of asthma, the nature of their antiasthmatic action remains obscure. Several possible biochemical mechanisms have been postulated, mainly from experiments with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Neither the legal research nor the analysis contained in this book is particularly original. What is original — and highly welcome — is the author's cogent, comprehensible, and instructive synthesis and presentation of legal principles and processes. This ...

No extract is available for articles shorter than 400 words.

Here is a concisely written book about the dynamics, politics, and changing philosophic underpinnings of federal consumer legislation since the mid-1960s. It encompasses the heady days of the late 1960s and early 1970s when Congress was enacting consumer-...

Gordon McLachlan and the Nuffield Provincial Hospitals Trust have once again made an important contribution to the literature of health-care policy and economics. Here we have a series of essays presenting the views of several authors in the United ...

With health-related expenditures by New York City now consuming more than 18 per cent of the city's revenues and total public and private expenditures exceeding $10 billion, Dr. Rosner relates the history of private hospitals from 1885 to 1915 as one ...

No tourist visas are granted for travel to the Kingdom of Saudi Arabia. Thus, all visitors are deemed to be usefully engaged in some aspect of the astounding and unprecented transformation that has descended on this expansive, wind-swept, and previously ...

A set of nine oral histories of women physicians who entered medical school between 1928 and 1974 cannot be construed as a survey, a definitive statement, a basis for generalization, or a map for future physicians. However, it can provide a glimpse of the ...

Huth has given us an excellent but frustrating book. It describes briefly, yet in great detail, precisely what goes into publishing a paper. It achieves a coherence that many books on medical writing lack. By taking us through each step of writing an ...

This is the fifth book — in six years — in which E. A. Murphy deals with quantitative aspects of medicine. It is not another run-of-the-mill biostatistics textbook. Rather, it is a unique, personal, "elementary account of statistics viewed from inside the ...

This is one of the books currently being written by physicians about the use of computers in the private office. I must report that in my opinion all such books fall far short of their intended mark and can be very misleading. This one is no exception.

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The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

TRAUMA

A symposium entitled "Trauma '83 — Point and Counterpoint" will be held at the Golden Nugget Hotel in Atlantic City, May 2–4. The fee is $395.

Contact the Trauma Dept., American College of Surgeons, 55 E. Erie St., Chicago, IL 60611.

PROGRAMS OF ...