The rapid onset of muscle wasting, protein depletion, and elevated urea excretion in patients with trauma¹ or sepsis² contrasts with the economic conservation of protein observed during starvation in the normal person.³ After a brief fast, infected and ...

Fever is a characteristic response of mammals and other vertebrates to infection, to microbial toxins, and to many noninfectious immune reactions.^{1 2 3} Although the increase in body temperature is initiated within thermoregulatory nuclei in the ...

Considerable progress was made during the 1960s in the treatment of some pediatric cancers — most notably, Wilms' tumor and acute lymphoblastic leukemia. This was not true for the non-Hodgkin's lymphomas of childhood. During the 1960s, only 15 per cent of ...

Type I glycogen-storage disease (von Gierke's disease) is due to a deficiency of glucose-6-phosphatase.¹ In a variant form of this disease, Type Ib, the clinical features are indistinguishable from those of typical glucose-6-phosphatase deficiency, but ...

Although the heart was formerly thought to be relatively resistant to radiation,¹ the increasing use of radiation therapy to the mediastinum has been associated with well-documented instances of cardiac abnormalities, including pericarditis with effusion ...

Granulomas may be found in up to 10 per cent of specimens from routine percutaneous liver biopsies.¹ Non-organ-specific antibodies to mitochondria occur in less than 1 per cent of the general population and in a similar proportion of patients with ...

It is currently believed that hypogonadotropic hypogonadism (or isolated gonadotropin deficiency) is secondary to lack of delivery of endogenous luteinizing hormone-releasing hormone to the pituitary gonadotrope, whereas delayed puberty is related to ...

Presentation of Case

A 25-year-old woman was admitted to the hospital because of syncope.

She was well until five days earlier, when she began to experience orthostatic dizziness, nausea, and sweating, accompanied by the passage of tarry stools. Crampy ...

The accelerated catabolism of skeletal-muscle protein that accompanies severe trauma or infection can now be ascribed to the actions of endogenously produced mediators. Two noteworthy studies described^{1 , 2} in this issue of the Journal have identified ...

Heart disease occurring after irradiation of the mediastinum was first recognized in the 1960s, when long-term survival after radiotherapy for Hodgkin's disease became frequent. Pericardial disease, in its various forms, is the most common problem, but ...

Sarcoidosis is a systemic granulomatous disorder of unknown cause that involves many organs. The most characteristic clinical presentations of sarcoidosis include pulmonary infiltrates, lymphadenopathy, fever, infiltrative skin lesions, and uveitis. In ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The 11 questions asked by DerSimonian and her colleagues (June 3 issue) with regard to 67 clinical trials published in four general weekly medical journals are deceptively simple.¹ Dented amour-propre required a quick in-house reanalysis ...

Those interested in liver physiology and disease have been subjected to (or treated to) a proliferation of journals and books. At least four new periodicals on the liver have been launched since 1980, and whereas one single-authored and one multiauthored ...

In their preface the editors state that there is need for a convenient and practical guide to the diagnosis and management of renal and hypertensive disorders. This may have been the case when this book was first conceived. The final product would have ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Dr. Hershman and his colleagues have put together a revision of their textbook that was first published in 1977. The book is organized into short chapters covering each of the major areas of endocrine disease, including diabetes mellitus, calcium and ...

Herodotus, a contemporary of Hippocrates considered to be "the father of history," warned: "Every measure undertaken with temerity is liable to be perplexed with error, and punished by misfortune." The editor and the 45 other authors of this book have ...

No extract is available for articles shorter than 400 words.

A textbook by a single author is uncommon today. Few individuals possess sufficient expertise to write authoritatively about the basic-science aspects, pathophysiology, and therapeutic aspects of a large number of disorders. Dr. Vasarinsh, however, has ...

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

CALL FOR PAPERS

The New England Rheumatism Society is now accepting abstracts for its annual scientific meeting at the Lahey Clinic Medical Center in Burlington, Mass., on May 20.

Contact Dr. Norman Kattwinkel, Lahey Clinic Fdn., 41 Mall Rd., Burlington, ...

The Centers for Disease Control (CDC), a respected federal agency that enjoys a worldwide reputation for its successful assaults against infectious disease, has broadened its programmatic scope to include disease that is related to the environment, ...