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Table of contents for

August 19, 1982  Vol. 307 No. 8

Original Articles
457-463

    HAPTOGLOBIN (Hp) is a hemoglobin-binding serum α2-globulin that is genetically determined by two autosomal codominant allelic genes, Hp 1 and Hp 2, which express themselves in three phenotypes designated as Hp 1–1, Hp 2–1, and Hp 2–2.1 , 2 Like other ...

    463-468

    SINCE the benchmark studies of Kass1 2 3 more than 20 years ago, a quantitative culture of midstream urine containing ≥105 bacteria per milliliter has been the criterion employed by nearly all physicians to establish the diagnosis of urinary-tract ...

    Special Article
    468-476

    INTERNIST-I, an experimental program for computer-assisted diagnosis in general internal medicine, differs considerably in scope from other medical diagnostic computer programs. In the past, techniques including mathematical modeling, use of Bayesian ...

    Medical Intelligence
    477-479

      IN North America and Western Europe, up to 50 per cent of the population escapes cytomegalovirus (CMV) infection during childhood and adolescence, whereas in some primitive cultures infection rates approach 100 per cent in early childhood.1 2 3 4 In ...

      479-481

      HAIRY-CELL leukemia (leukemic reticuloendotheliosis) is a disorder in which mononuclear leukocytes with characteristic filamentous cytoplasmic villae ("hairy" cells) accumulate in peripheral blood, spleen, and bone marrow. The typical presentation ...

      481-484

        NEONATAL biliary atresia was originally thought to be a developmental malformation. However, microscopical examination of bile ducts resected during portoenterostomy has revealed inflammatory lesions suggesting an ongoing postnatal process such as ...

        Case Records of the Massachusetts General Hospital
        485-492

        Presentation of Case

        A 16-year-old boy was admitted to the hospital with the diagnosis of pancreatitis.

        He was in generally good health until three days earlier, when abdominal pain and vomiting developed shortly after a dinner of spaghetti. He slept ...

        Editorials
        493-494

        For a number of years it has been predicted that the use of computer technology would result in radical changes in the storage and retrieval of medical data. Only in the past five years, however, have there been major changes in the management of ...

        495-496

        Hairy-cell leukemia is a well-defined disorder characterized by splenomegaly, pancytopenia, and morphologically typical neoplastic mononuclear cells in the blood and bone marrow. Since the description of this disease as leukemic reticuloendotheliosis by ...

        Sounding Board
        496-497

        Economists have been arguing for some time that the reason costs in the medical sector of the economy are rising so rapidly is that the medical market is inefficient. Some argue that it is inherently inefficient and advocate a regulatory approach to cost ...

        Massachusetts Medical Society
        497

        No extract is available for articles shorter than 400 words.

        Correspondence
        498

        To the Editor: Recently described cases of aggressive lymphadenopathic and visceral Kaposi's sarcoma in the United States have occurred in homosexual men.1 2 3 We have observed a similar case in a heterosexual drug addict.

        A 28-year-old man was admitted ...

        498

        No extract is available for articles shorter than 400 words.

        498-499

        No extract is available for articles shorter than 400 words.

        499-500

        To the Editor: During a routine screening in late 1980 of data on adverse reactions received through the Food and Drug Administration's Spontaneous Reporting System, we observed what appeared to be an excessive number of reports in which tolmetin sodium (...

        500-501

        No extract is available for articles shorter than 400 words.

        501

        No extract is available for articles shorter than 400 words.

        501

        No extract is available for articles shorter than 400 words.

        501-502

        No extract is available for articles shorter than 400 words.

        502

        No extract is available for articles shorter than 400 words.

        503

        No extract is available for articles shorter than 400 words.

        503

        To the Editor: One reason that the hepatitis B vaccine has been somewhat slow in appearing on the market is that the manufacturing company has been trying to stockpile enough of it to meet the huge anticipated initial demand. When the vaccine becomes ...

        503-504

        No extract is available for articles shorter than 400 words.

        504-506

        No extract is available for articles shorter than 400 words.

        506

        To the Editor: Dr. Berry1 and others who decried the proliferation of scientific journals might well ask why their pleas and those of earlier generations were, for all intents and purposes, ignored. The fact is that most medical scientists manage, one ...

        506

        No extract is available for articles shorter than 400 words.

        Occasional Notes
        506-509

        IT has been three years since my first symptoms suggested a diagnosis of amyotrophic lateral sclerosis (ALS). The pain and anguish of this illness are known to most physicians and are an inevitable accompaniment of the disease, but there are other ...

        Book Reviews
        509

        As the editor states in his preface: "This textbook deals with the biochemistry of mammalian cells and relates the biochemical events at the cellular level to the physiological processes occurring in the whole animal. The topics were selected to meet the ...

        509

        No extract is available for articles shorter than 400 words.

        509-510

        No extract is available for articles shorter than 400 words.

        510

        No extract is available for articles shorter than 400 words.

        510

        No extract is available for articles shorter than 400 words.

        510-511

        No extract is available for articles shorter than 400 words.

        511

        Over the past year, the field of oncology has benefited greatly from the appearance of a number of major textbooks (Cancer Medicine, edited by Holland and Frei; Cancer: Principles and practice of oncology, edited by DeVita, Hellman, and Rosenberg; and ...

        Books Received
        511-512

        Basic Science

        Epidemiologic Research: Principles and quantitative methods. By David G. Kleinbaum, Lawrence L. Kupper, and Hal Morgenstern. 529 pp. Belmont, Calif., Lifetime Learning Publications, 1982. $38.50.

        Evaluation of Diagnostic Systems: Methods ...

        Notices
        512

        ACUPUNCTURE

        A course entitled "Acupuncture: Complete 100-Hour Certification Intensive" will be held in Roscoe, N.Y., September 11–24

        Contact Dr. Ralph Alan Dale, The Acupuncture Education Ctr., RD #1. Box 74A, Muhlig Rd., Parksville, NY 12768; or call (...

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