Beta-thalassemia is a disease characterized by decreased (β+) or absent (γ0) production of the β subunit of adult hemoglobin (hemoglobin A = α₂β₂). Decreased synthesis of β globin results in a relative excess of α-globin molecules that precipitate and ...

NAUSEA and vomiting are being increasingly recognized as factors limiting completion of a prescribed course of chemotherapy in patients with cancer. Although pharmacologic agents such as prochlorperazine, tetrahydrocannabinol, and metoclopramide have had ...

Hepatitis B virus (HBV) infection remains a threat to both medical staff and patients in hemodialysis centers.^{1 , 2} Although the incidence of infection has declined dramatically in the United States since the introduction of disposable equipment and the ...

AN important question facing physicians today is whether to recommend cardiac catheterization to the patient who has just had an acute myocardial infarction. Although it has long been recognized that information obtained from cardiac catheterization ...

Maple-syrup-urine disease, also known as branched-chain ketoaciduria, results from a primary defect in oxidative decarboxylation of the ketoacids derived from the branched-chain amino acids leucine, isoleucine, and valine.¹ Neonates with the most common ...

Chronic immune thrombocytopenic purpura (ITP) appeared in monozygotic twin girls during adolescence. An older sister was discovered to have less severe thrombocytopenia without purpura. Increased amounts of platelet-associated immunoglobulin were detected ...

IN 1897 Ehrlich¹ coined the term "horror autotoxicus" to describe his view that the body seemed "unwilling" to mount an immune assault on its own tissues. In the early part of this century, with the hypothesis that the hyperplastic thymus gland might, in ...

Presentation of Case

First admission. A 62-year-old man was admitted to the hospital because of a question of subarachnoid hemorrhage.

He was in excellent health until the evening of admission, when he experienced the sudden onset of a frontal headache ...

Current policies of the federal government include substantial cuts in government health expenditures and dismantling government regulations in the health and medical-care sectors. These policies are being pursued under an assumed popular mandate. The ...

The art of the molecular geneticist is no longer confined to the elegant but arcane domain of simple microbial genomes. Recombinant-DNA technology has rendered equally susceptible to his wizardry the several billion base pairs of DNA present in each human ...

Medical confidentiality, as it has traditionally been understood by patients and doctors, no longer exists. This ancient medical principle, which has been included in every physician's oath and code of ethics since Hippocratic times, has become old, worn-...

DEATHS

DeCesare — Nicandro Francis DeCesare, M.D., of Methuen, died on October 29. He was in his 88th year.

Dr. DeCesare received his degree from Tufts College Medical School in 1920. He was a member of the American Medical Association, the American ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In the July 29 issue of the Journal,¹ Dr. Freis discussed the Hypertension Detection and Follow-up Program (HDFP). We believe he has several misconceptions about the HDFP.

The HDFP was designed to test the effect on mortality of intensive ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases has initiated a multicenter clinical trial — the Diabetes Control and Complications Trial (DCCT) — to address the issue of the relation between metabolic ...

No extract is available for articles shorter than 400 words.

To the Editor: Although ethanol therapy has been used for the treatment of methyl alcohol intoxication for several years, there are few data on its effectiveness. We observed a patient who received prompt and aggressive ethanol therapy for methanol ...

To the Editor: In the July 29 issue Donabedian et al. reported that in a prospective trial of levamisole in a large group of patients with Job's syndrome (which includes chronic eczema, recurrent staphylococcal infections, eosinophilia, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Articles written for medical journals usually take quite a while to appear in print; six months from submission of typescript to appearance of galley proofs is not an unusual interval. No real harm is done, since articles of major ...

The conservative political mood in the United States and the apparent failure of law-enforcement agencies to curb violent crime have resulted in a resurgence of support for the death penalty across the country. Fifteen years ago, a majority of Americans ...

In this unique book, Dr. Goodwin and her coauthors have integrated their extensive clinical experience in evaluating and treating incest victims with a careful review of the literature. The result is a comprehensive and clinically astute view of sexual ...

The title and size of this book encourage the reviewer to view its publication as a momentous event. I, like others who have labored in the "common ground" made graphic by the Venn diagram (on the book's jacket), approached the book with happy ...

In 1948 Milton Senn, a pioneer in the introduction of psychologic concepts into pediatric practice, envisioned that pediatricians would develop a balanced competency in both the psychosocial and biomedical aspects of child health. In 1978 the Task Force ...

Since its first appearance in 1974, the Primer has been a popular manual for psychiatric residents beginning therapeutic work with children. The publication of a second edition of this useful textbook is a welcome event.

The book is divided into three ...

No extract is available for articles shorter than 400 words.

There is an ever-increasing awareness of the need for professionals to serve as advocates for children who are congenitally handicapped. Children Who Are Different was specifically developed for professionals working with handicapped children and their ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

KILLINGTON PSYCHIATRY CONFERENCE

The Killington Psychiatry Conference will be held in Killington, Vt., February 6–11.

Contact Wilma Guerette, Northeast Conferences, P.O. Box 966, Lenox, MA 01240; or call (413) 637–0101.

POSTRESIDENCY FELLOWSHIPS

The ...