Deaths from gram-negative bacteremia continue to occur at a high frequency despite the advent of potent antibiotics and aggressive support techniques.^{1 , 2} Antibiotic resistance and the severity of underlying disease account in part for the failure of ...

Standard cytogenetic techniques applied to cells obtained from biopsy specimens of lymph nodes frequently yield unsatisfactory results, with low mitotic indexes (0.001 to 0.1 per cent) and contracted chromosomes displaying poorly differentiated banding ...

The central event in the initiation of puberty appears to be the episodic discharge of the hypothalamic gonadotropin-releasing hormone, GnRH. In early puberty, GnRH release, as reflected by pulsations of luteinizing hormone, appears to occur in a ...

Like practitioners of most other medical and surgical subspecialties, orthopedists are coming under increasing pressure to defend the introduction and use of expensive new technology, including total hip replacement. Quantitative data on the actual need ...

(Second of Two Parts)

Epidemiology

Approximately 200 studies of the geographic distribution of multiple sclerosis have been conducted.⁶⁰ They have shown regions of high prevalence (30 to 80 cases per 100,000 population) in northern Europe between 65 and ...

The majority (80 per cent) of patients with acute lymphoblastic leukemia (ALL) have neither cell-surface immunoglobulin nor T-cell-associated surface antigens that would clearly identify the disease as having either a B-cell or a T-cell lineage.¹ Two ...

Schoolmates of patients with meningococcal disease have not been considered to be at increased risk for the development of disease due to Neisseria meningitidis.^{1 , 2} Within a six-day period N. meningitidis serogroup C disease occurred in five children ...

Presentation of Case

A 63-year-old woman was admitted to the hospital because of left facial weakness and hypercalcemia.

There was a long history of hypertension, which was treated with clonidine and chlorthalidone. Five months before admission she began ...

When someone falls ill with bacterial meningitis, there is understandable concern among those who live or work with the patient about the contagiousness of the disease. When two or more cases occur in a group of people, concern often increases toward ...

Bacteremia due to gram-negative rods is an important cause of morbidity and mortality, particularly in immunosuppressed patients. In 1974 a special study group on gram-negative bacteremia of the Department of Health, Education, and Welfare estimated that ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The figures quoted by Shinnar et al. (June 17 issue)¹ for the incidence and mortality rates of intraventricular hemorrhage may be influenced by the definition of their population. Intracranial hemorrhage is frequently diagnosed on the ...

No extract is available for articles shorter than 400 words.

To the Editor: We agree with Drs. Lees and Lees that "no one has shown that raising HDL [high-density-lipoprotein] cholesterol or apoprotein concentrations reduces the risk of atherosclerosis" (June 24 issue).¹ However, we believe that the weight of ...

No extract is available for articles shorter than 400 words.

To the Editor: Craven et al. suggest that mechanical ventilator tubing need be changed only every 48 hours, rather than every 24 hours, as is common practice (June 24 issue).¹ We applaud them for conducting this randomized study, which could potentially ...

To the Editor: A workman installing wall-to-wall carpeting in one of our homes, and another doing the same work in our office, described bilateral pain and unilateral effusion of the knee, which required multiple arthrocenteses. We noted that such ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We studied the bimanual dexterity and handedness involved in hitting a baseball in groups of professional players and in controls. The professional players were separated into three groups. The first group comprised all recorded major-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Cannabis has long been used as a primitive medicine. The heyday of its medical application in the Western world was the period 1840 to 1900. Physicians of a century ago knew far more about it and were much more interested in exploring its therapeutic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The stated purpose of this book is to present the state of the art and science of psychiatric treatments in practice today. A comprehensive survey is provided, organized according to individual mental disorders, using the classification in the American ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of new ...

CALL FOR PAPERS

Abstracts are now being accepted for an international conference on predictive drug testing on human tumor cells. The conference will be held at the University Hospital of Zurich, Switzerland, July 20–22. The deadline for receipt of ...

For at least a decade policy makers have been trying to contain health-care costs while maintaining access to care. The "financially distressed" hospital epitomizes the conflict between costs and access that makes this task so difficult. Financial ...

The federal government, facing massive budget deficits and the expectation that Medicare costs will double to $110 billion by 1987 if there are no changes in present trends, has approved another round of sweeping policies to curtail this growth and, for ...