The mechanism of altered myocardial function in hyperthyroidism has been the subject of clinical and experimental investigation over several decades.¹ Despite the striking similarities between the effects of excessive circulating thyroid hormones and ...

Our laboratory is engaged in a morphometric study of normal^{1 2 3 4} and abnormal growth of the human lung. We hypothesized that lung growth might be quantitatively or qualitatively abnormal in patients with congenital heart disease, and therefore we ...

Circulating immune complexes have been demonstrated in a number of disease states, including some malignant neoplasms.^{1 2 3} In several of these diseases, inflammatory reactions and vascular lesions are considered to be consequences of immunecomplex ...

Intracoronary infusion of streptokinase in patients with acute myocardial infarction is an exciting and innovative technique for reperfusion of the ischemic myocardium,^{1 2 3 4} but its net benefits have not yet been reliably estimated.

Intravenous infusion ...

(First of Two Parts)

The lesions of multiple sclerosis were probably described as early as 1838,¹ but it was Charcot in 1868² who recognized the characteristic clinical and pathologic features of the disease. Since that time, the disorder has been studied ...

Theophylline (1,3-dimethylxanthine) is a constituent of numerous bronchodilator preparations and is widely used in the treatment of patients with obstructive airways disease. Its metabolism is complex and incompletely understood, involving hepatic ...

Combined factor V and factor VIII deficiency is a well-documented hereditary bleeding disorder that has so far been reported in 21 families.^{1 , 2} The study of this disorder is of great interest, since the normal function of factor V and factor VIII is ...

Presentation of Case

A 38-year-old woman was admitted to the hospital because of recurrent epigastric pain.

She was well until three years earlier, when she began to have bouts of pain and tightness in the epigastrium and back after the birth of her third ...

The cardiac manifestations of hyperthyroidism have long been recognized as among the earliest and most consistent features of this disorder. The association of palpitations, tachycardia, and cardiomegaly with thyroid-gland enlargement and exophthalmos was ...

Antigen–antibody immune complexes can activate a variety of cell types, interact with humoral factors, and induce the release of biologically active mediators that participate directly in disease processes. Moreover, immune complexes have profound effects ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The paper by Anhalt et al. (May 20 issue)¹ demonstrates that the passive transfer of IgG from patients with pemphigus induces the disease in neonatal mice and provides one more piece of evidence for a pathogenic role of pemphigus ...

No extract is available for articles shorter than 400 words.

To the Editor: Resistance of Neisseria gonorrhoeae to killing by fresh normal human serum may be an important factor in the pathogenesis of gonorrhea.¹ Most strains isolated from disseminated gonococcal infections are resistant to the bactericidal action ...

No extract is available for articles shorter than 400 words.

To the Editor: Some 25 to 60 per cent of patients with major depression have hypothalamic-pituitary-adrenal overactivity, manifested by nonsuppression of Cortisol, after overnight administration of dexamethasone.¹ Some workers think that this ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is an undoubted American classic. First published in 1927, it was edited in its first seven editions by Cecil, in editions 8, 9, and 10 by Cecil and Loeb, and in editions 11 through 14 by Beeson and McDermott, joined by Wyngaarden in the 15th. Now, ...

Clinical Internal Medicine in the Aged represents the unique effort of a major medical school to state clearly its position on the responsibility of the internist treating the elderly patient. The book is written exclusively by the faculty of the ...

In many chapters, the many authors of this clinical manual discuss diverse aspects of diabetes, including its management, acute and chronic complications, and impact on other organs and metabolic systems. Four copious appendixes offer patients a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of new ...

MEETING OF THE AMERICAN MEDICAL WRITERS ASSOCIATION

Dr. Mahlon Hoagland, President and Director of the Worcester Foundation for Experimental Biology, will discuss "How Basic Research is Communicated within the Medical Profession and the Public" at a ...